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FAS elisa kit :: Chicken Factor Related Apoptosis (FAS) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS260839 FAS elisa kit
Unit / Price
48-Strip-Wells  /  $315 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,825 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,425 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Factor Related Apoptosis (FAS), ELISA Kit

 Also Known As   

Chicken Factor Related Apoptosis (FAS) ELISA Kit

 Product Gene Name   

FAS elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 OMIM    614592
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 Species Reactivity    Chicken
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of FAS elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for FAS purchase    MBS260839 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Factor Related Apoptosis (FAS) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FAS. The ELISA analytical biochemical technique of the MBS260839 kit is based on FAS antibody-FAS antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FAS antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FAS. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for FAS. It may not necessarily be applicable to this product.
 NCBI GI #    120049
 NCBI GeneID    2263
 NCBI Accession #    P21802.1 [Other Products]
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 UniProt Secondary Accession #    P18443; Q01742; Q12922; Q14300; Q14301; Q14302; Q14303; Q14304; B4DFC2; E7EVR6; E9PCR0 [Other Products]
 UniProt Related Accession #    P21802 [Other Products]
 Molecular Weight    79,833 Da
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 NCBI Official Full Name    Fibroblast growth factor receptor 2
 NCBI Official Synonym Full Names    fibroblast growth factor receptor 2
 NCBI Official Symbol    FGFR2 [Similar Products]
 NCBI Official Synonym Symbols   
BEK; JWS; BBDS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM
[Similar Products]
 NCBI Protein Information    fibroblast growth factor receptor 2; FGFR-2; FGF receptor; soluble FGFR4 variant 4; bacteria-expressed kinase; hydroxyaryl-protein kinase; FGFR2-AHCYL1 fusion kinase protein; keratinocyte growth factor receptor; BEK fibroblast growth factor receptor; protein tyrosine kinase, receptor like 14
 UniProt Protein Name    Fibroblast growth factor receptor 2
 UniProt Synonym Protein Names   
K-sam; KGFR; Keratinocyte growth factor receptor; CD_antigen: CD332
 Protein Family    Tumor necrosis factor receptor superfamily
 UniProt Gene Name    FGFR2 [Similar Products]
 UniProt Synonym Gene Names    BEK; KGFR; KSAM; FGFR-2; KGFR [Similar Products]
 UniProt Entry Name    FGFR2_HUMAN
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 NCBI Summary for FAS    The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]
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 UniProt Comments for FAS    FGFR2: a receptor tyrosine kinase of the highly-conserved FGFR family that binds fibroblast growth factor (FGF). Mutations are associated with many craniosynostotic syndromes and bone malformations. Mutations cause syndromes with defects in facial and limb development, including Crouzon syndrome, Beare-Stevenson cutis gyrata syndrome, Pfeiffer syndrome, Apert syndrome, and Jackson-Weiss syndrome. Somatic mutations seen in gastric cancer. Amplified in gastric, breast and some B cell cancers, but deleted in glioblastoma Twenty splice-variant isoforms have been described.

Protein type: Protein kinase, TK; Protein kinase, tyrosine (receptor); Oncoprotein; Membrane protein, integral; Kinase, protein; EC 2.7.10.1; TK group; FGFR family

Chromosomal Location of Human Ortholog: 10q26

Cellular Component: Golgi apparatus; cell surface; intracellular membrane-bound organelle; integral to plasma membrane; cytoplasmic membrane-bound vesicle; integral to membrane; extracellular region; excitatory synapse; cell cortex; nucleoplasm; extracellular matrix; membrane; cytoplasm; plasma membrane; nucleus

Molecular Function: heparin binding; protein binding; fibroblast growth factor binding; protein homodimerization activity; fibroblast growth factor receptor activity; protein-tyrosine kinase activity; ATP binding

Biological Process: nerve growth factor receptor signaling pathway; mesodermal cell differentiation; embryonic pattern specification; post-embryonic development; embryonic organ morphogenesis; morphogenesis of embryonic epithelium; cell-cell signaling; embryonic digestive tract morphogenesis; midbrain development; positive regulation of mesenchymal cell proliferation; ventricular cardiac muscle morphogenesis; neuromuscular junction development; positive regulation of cardiac muscle cell proliferation; inner ear morphogenesis; fibroblast growth factor receptor signaling pathway; cell fate commitment; regulation of osteoblast differentiation; regulation of fibroblast growth factor receptor signaling pathway; positive regulation of cell cycle; embryonic cranial skeleton morphogenesis; neuroblast division in the ventricular zone; organ growth; organ morphogenesis; mesenchymal cell differentiation; positive regulation of cell division; negative regulation of mitosis; embryonic organ development; gland morphogenesis; positive regulation of transcription from RNA polymerase II promoter; alveolus development; positive regulation of epithelial cell proliferation; peptidyl-tyrosine phosphorylation; branching morphogenesis of a nerve; apoptosis; positive regulation of smooth muscle cell proliferation; protein amino acid autophosphorylation; pyramidal neuron development; negative regulation of transcription from RNA polymerase II promoter; orbitofrontal cortex development; bone mineralization; odontogenesis; regulation of osteoblast proliferation; epithelial cell differentiation; positive regulation of MAPKKK cascade; ureteric bud development; epidermis morphogenesis; regulation of smooth muscle cell differentiation; positive regulation of cell proliferation; angiogenesis; lacrimal gland development; otic vesicle formation; positive regulation of Wnt receptor signaling pathway; negative regulation of epithelial cell proliferation; epidermal growth factor receptor signaling pathway; hair follicle morphogenesis; phosphoinositide-mediated signaling; in utero embryonic development; multicellular organism growth; synaptic vesicle transport; regulation of multicellular organism growth; limb bud formation; axonogenesis; gut development; skeletal morphogenesis; regulation of cell fate commitment; insulin receptor signaling pathway; innate immune response; epithelial to mesenchymal transition; reproductive structure development; lung development; regulation of smoothened signaling pathway

Disease: Pfeiffer Syndrome; Lacrimoauriculodentodigital Syndrome; Scaphocephaly, Maxillary Retrusion, And Mental Retardation; Apert Syndrome; Gastric Cancer; Jackson-weiss Syndrome; Crouzon Syndrome; Beare-stevenson Cutis Gyrata Syndrome; Bent Bone Dysplasia Syndrome; Antley-bixler Syndrome Without Genital Anomalies Or Disordered Steroidogenesis; Saethre-chotzen Syndrome
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 Research Articles on FAS    1. Activated FGFR is associated with chordoma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with FAS elisa kitDiseases associated with FAS elisa kit
 Products by Pathway  Pathway Diagram
 Activated Point Mutants Of FGFR2 Pathway antibodies  Activated Point Mutants Of FGFR2 Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Angiogenesis Pathway antibodies  Angiogenesis Pathway Diagram
 Constitutive PI3K/AKT Signaling In Cancer Pathway antibodies  Constitutive PI3K/AKT Signaling In Cancer Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Downstream Signal Transduction Pathway antibodies  Downstream Signal Transduction Pathway Diagram
 Downstream Signaling Events Of B Cell Receptor (BCR) Pathway antibodies  Downstream Signaling Events Of B Cell Receptor (BCR) Pathway Diagram
 Downstream Signaling Of Activated FGFR Pathway antibodies  Downstream Signaling Of Activated FGFR Pathway Diagram
 Disease Name  Pubmed Publications
 Craniofacial Abnormalities Antibodies  >409 publications with FAS and Craniofacial Abnormalities
 Craniosynostoses Antibodies  >331 publications with FAS and Craniosynostoses
 Skin Diseases Antibodies  >250 publications with FAS and Skin Diseases
 Limb Deformities, Congenital Antibodies  >220 publications with FAS and Limb Deformities, Congenital
 Breast Neoplasms Antibodies  >213 publications with FAS and Breast Neoplasms
 Pfeiffer type acrocephalosyndactyly Antibodies  >202 publications with FAS and Pfeiffer type acrocephalosyndactyly
 Acrocephalosyndactylia Antibodies  >202 publications with FAS and Acrocephalosyndactylia
 Craniofacial Dysostosis Antibodies  >96 publications with FAS and Craniofacial Dysostosis
 Abnormalities, Multiple Antibodies  >85 publications with FAS and Abnormalities, Multiple
 Stomach Neoplasms Antibodies  >61 publications with FAS and Stomach Neoplasms
Organs/Tissues associated with FAS elisa kit
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >284 publications with FAS and Bone
 Embryonic Tissue Antibodies  >206 publications with FAS and Embryonic Tissue
 Brain Antibodies  >157 publications with FAS and Brain
 Lung Antibodies  >145 publications with FAS and Lung
 Skin Antibodies  >133 publications with FAS and Skin
 Vascular Antibodies  >125 publications with FAS and Vascular
 Prostate Antibodies  >87 publications with FAS and Prostate
 Stomach Antibodies  >81 publications with FAS and Stomach
 Muscle Antibodies  >79 publications with FAS and Muscle
 Eye Antibodies  >78 publications with FAS and Eye
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