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HNRNP L elisa kit :: Chicken Heterogeneous Nuclear Ribonucleoprotein L ELISA Kit

Scan QR to view Datasheet Catalog #    MBS006061 HNRNP L elisa kit
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 Product Name   

Heterogeneous Nuclear Ribonucleoprotein L (HNRNP L), ELISA Kit

 Also Known As   

Chicken Heterogeneous Nuclear Ribonucleoprotein L ELISA Kit

 Product Gene Name   

HNRNP L elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 19; NC_000019.9 (39327028..39342979, complement). Location: 19q13.2
 OMIM    164021
 3D Structure    ModBase 3D Structure for P14866
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 Species Reactivity    Chicken
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of HNRNP L elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for HNRNP L purchase    MBS006061 is a ready-to-use microwell, strip-or-full plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Heterogeneous Nuclear Ribonucleoprotein L (HNRNP L) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HNRNP L. The ELISA analytical biochemical technique of the MBS006061 kit is based on HNRNP L antibody-HNRNP L antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HNRNP L antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HNRNP L. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for HNRNP L. It may not necessarily be applicable to this product.
 NCBI GI #    52632385
 NCBI GeneID    3191
 NCBI Accession #    NP_001005335.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001005335.1 [Other Products]
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 UniProt Primary Accession #    P14866 [Other Products]
 UniProt Secondary Accession #    Q9H3P3; A6ND69; A6NIT8 [Other Products]
 UniProt Related Accession #    P14866 [Other Products]
 Molecular Weight    64,133 Da
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 NCBI Official Full Name    heterogeneous nuclear ribonucleoprotein L isoform b
 NCBI Official Synonym Full Names    heterogeneous nuclear ribonucleoprotein L
 NCBI Official Symbol    HNRNPL [Similar Products]
 NCBI Official Synonym Symbols   
HNRPL; hnRNP-L; P/OKcl.14
[Similar Products]
 NCBI Protein Information    heterogeneous nuclear ribonucleoprotein L; hnRNP L
 UniProt Protein Name    Heterogeneous nuclear ribonucleoprotein L
 Protein Family    Heterogeneous nuclear ribonucleoprotein
 UniProt Gene Name    HNRNPL [Similar Products]
 UniProt Synonym Gene Names    HNRPL; hnRNP L [Similar Products]
 UniProt Entry Name    HNRPL_HUMAN
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 NCBI Summary for HNRNP L    Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for HNRNP L    hnRNP L: This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Is associated with most nascent transcripts including those of the landmark giant loops of amphibian lampbrush chromosomes. Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA splicing; RNA-binding

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: nucleoplasm; membrane; cytoplasm; nucleus; ribonucleoprotein complex

Molecular Function: protein binding; RNA binding; nucleotide binding

Biological Process: nuclear mRNA splicing, via spliceosome; RNA processing; RNA splicing; gene expression
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 Research Articles on HNRNP L    1. Induction of caspase-9b expression is due to activation of hnRNP L via phosphorylation to compete/inhibit hnRNP U association with exon 3 of Casp9 mRNA.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with HNRNP L elisa kitPathways associated with HNRNP L elisa kit
 Reference Product  PubMed Publications
 HNRNPC elisa kit  >1 publications with HNRNP L and HNRNPC
 HNRNPM elisa kit  >1 publications with HNRNP L and HNRNPM
 HNRNPA2B1 elisa kit  >1 publications with HNRNP L and HNRNPA2B1
 HNRNPK elisa kit  >1 publications with HNRNP L and HNRNPK
 Products by Pathway  Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Processing Of Capped Intron-Containing Pre-mRNA Pathway antibodies  Processing Of Capped Intron-Containing Pre-mRNA Pathway Diagram
 MRNA Splicing Pathway antibodies  MRNA Splicing Pathway Diagram
 MRNA Splicing - Major Pathway antibodies  MRNA Splicing - Major Pathway Diagram
 MRNA Processing Pathway antibodies  MRNA Processing Pathway Diagram
Diseases associated with HNRNP L elisa kitOrgans/Tissues associated with HNRNP L elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >2 publications with HNRNP L and Neoplasms
 Nervous System Diseases Antibodies  >1 publications with HNRNP L and Nervous System Diseases
 Necrosis Antibodies  >1 publications with HNRNP L and Necrosis
 Inflammation Antibodies  >1 publications with HNRNP L and Inflammation
 Breast Neoplasms Antibodies  >1 publications with HNRNP L and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >1 publications with HNRNP L and Vascular
 Embryonic Tissue Antibodies  >1 publications with HNRNP L and Embryonic Tissue
 Testis Antibodies  >1 publications with HNRNP L and Testis
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