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IP3 elisa kit :: Chicken Inositol Triphosphate ELISA Kit

Scan QR to view Datasheet Catalog #    MBS038603 IP3 elisa kit
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Inositol Triphosphate (IP3), ELISA Kit

 Also Known As   

Chicken Inositol Triphosphate ELISA Kit

 Product Gene Name   

IP3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q63269
 Species Reactivity    Chicken
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Assay Type    Quantitative Sandwich
 Detection Range    31.2pg/ml-1000pg/ml
 Sensitivity    5.0pg/ml
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IP3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IP3 purchase    MBS038603 is a ready-to-use microwell, strip-or-full plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Inositol Triphosphate (IP3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 31.2pg/ml-1000pg/ml in biological research samples containing IP3, with an estimated sensitivity of 5.0pg/ml. The ELISA analytical biochemical technique of the MBS038603 kit is based on IP3 antibody-IP3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IP3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IP3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for IP3 elisa kit

   Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of IP3 (hereafter termed "analyte") in undiluted original Chicken body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS038603. Click to request current manual
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NCBI/Uniprot data below describe general gene information for IP3. It may not necessarily be applicable to this product.
 NCBI GI #    310171
 NCBI GeneID    25679
 NCBI Accession #    AAA41446.1 [Other Products]
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 UniProt Primary Accession #    Q63269 [Other Products]
 UniProt Related Accession #    Q63269 [Other Products]
 Molecular Weight    304,286 Da
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 NCBI Official Full Name    inositol triphosphate receptor subtype 3
 NCBI Official Synonym Full Names    inositol 1,4,5-trisphosphate receptor, type 3
 NCBI Official Symbol    Itpr3 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    inositol 1,4,5-trisphosphate receptor type 3; IP3R 3; IP3R-3; insP3R3; IP3 receptor; type 3 InsP3 receptor; inositol 1,4,5-triphosphate receptor 3; inositol 1,4,5-triphosphate receptor, type 3; type 3 inositol 1,4,5-trisphosphate receptor
 UniProt Protein Name    Inositol 1,4,5-trisphosphate receptor type 3
 UniProt Synonym Protein Names   
IP3 receptor isoform 3; IP3R 3; InsP3R3; Type 3 inositol 1,4,5-trisphosphate receptor
 UniProt Gene Name    Itpr3 [Similar Products]
 UniProt Synonym Gene Names    IP3R 3; InsP3R3 [Similar Products]
 UniProt Entry Name    ITPR3_RAT
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 NCBI Summary for IP3    receptor for Inositol 1,4,5-trisphosphate (IP3); involved in second messenger signaling [RGD, Feb 2006]
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 UniProt Comments for IP3    IP3R3: a multi-pass endoplasmic reticulum membrane receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. Expressed in intestinal crypt and villus epithelial cells. The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region. Phosphorylated on tyrosine residues. Phosphorylated by AKT1 on serine and/or threonine residues. Belongs to the InsP3 receptor family.

Protein type: Membrane protein, multi-pass; Channel, calcium; Channel, ligand-gated; Membrane protein, integral

Cellular Component: nuclear outer membrane; endoplasmic reticulum membrane; endoplasmic reticulum; integral to plasma membrane; dendrite; integral to membrane; nuclear envelope; nucleoplasm; membrane; cell soma; perinuclear region of cytoplasm; apical part of cell; cytoplasm; plasma membrane; nucleolus; nucleus; receptor complex; brush border; myelin sheath

Molecular Function: inositol 1,3,4,5 tetrakisphosphate binding; inositol hexakisphosphate binding; calcium ion transmembrane transporter activity; calcium ion binding; intracellular ligand-gated calcium channel activity; phosphoinositide binding; inositol 1,4,5-triphosphate-sensitive calcium-release channel activity

Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; sensory perception of umami taste; inositol phosphate-mediated signaling; sensory perception of sweet taste; protein heterooligomerization; calcium ion transport; sensory perception of bitter taste; response to calcium ion; memory; protein homooligomerization
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 Research Articles on IP3    1. Physiologically relevant reactive oxygen species controls cytoplasmic and mitochondrial calcium transport through IP3R3.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with IP3 elisa kitDiseases associated with IP3 elisa kit
 Products by Pathway  Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Cholinergic Synapse Pathway antibodies  Cholinergic Synapse Pathway Diagram
 Circadian Entrainment Pathway antibodies  Circadian Entrainment Pathway Diagram
 Circadian Entrainment Pathway antibodies  Circadian Entrainment Pathway Diagram
 Dopaminergic Synapse Pathway antibodies  Dopaminergic Synapse Pathway Diagram
 Dopaminergic Synapse Pathway antibodies  Dopaminergic Synapse Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >4 publications with IP3 and Neoplasms
 Diabetes Mellitus, Type 1 Antibodies  >4 publications with IP3 and Diabetes Mellitus, Type 1
 Heart Diseases Antibodies  >3 publications with IP3 and Heart Diseases
 Disease Models, Animal Antibodies  >2 publications with IP3 and Disease Models, Animal
 Carcinoma Antibodies  >2 publications with IP3 and Carcinoma
 Adenocarcinoma Antibodies  >2 publications with IP3 and Adenocarcinoma
 Liver Neoplasms Antibodies  >1 publications with IP3 and Liver Neoplasms
 Breast Neoplasms Antibodies  >1 publications with IP3 and Breast Neoplasms
 Cognition Disorders Antibodies  >1 publications with IP3 and Cognition Disorders
 Memory Disorders Antibodies  >1 publications with IP3 and Memory Disorders
Organs/Tissues associated with IP3 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >6 publications with IP3 and Brain
 Colon Antibodies  >4 publications with IP3 and Colon
 Eye Antibodies  >2 publications with IP3 and Eye
 Lung Antibodies  >1 publications with IP3 and Lung
 Embryonic Tissue Antibodies  >1 publications with IP3 and Embryonic Tissue
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