NP_001035835.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
11,981 Da
NCBI Official Full Name
insulin, isoform 2
NCBI Official Synonym Full Names
INS-IGF2 readthrough
NCBI Official Synonym Symbols
NCBI Protein Information
insulin, isoform 2; INS-IGF2 readthrough transcript protein; insulin- insulin-like growth factor 2 read-through product
UniProt Protein Name
Insulin, isoform 2
UniProt Synonym Protein Names
INS-IGF2 readthrough transcript protein
UniProt Entry Name
INSR2_HUMAN
NCBI Summary for IAA
This locus includes two alternatively spliced read-through transcript variants which align to the INS gene in the 5' region and to the IGF2 gene in the 3' region. One transcript is predicted to encode a protein which shares the N-terminus with the INS protein but has a distinct and longer C-terminus, whereas the other transcript is a candidate for nonsense-mediated decay (NMD). The transcripts are imprinted and are paternally expressed in the limb and eye. [provided by RefSeq, Jul 2008]
UniProt Comments for IAA
INS-IGF2: 2 isoforms of the human protein are produced by alternative splicing
Chromosomal Location of Human Ortholog: 11p15.5
Cellular Component: extracellular region
Molecular Function: hormone activity
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Pathways associated with IAA elisa kit
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