NP_036720.2
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Related Accession #
Molecular Weight
31,680 Da
NCBI Official Full Name
insulin-like growth factor-binding protein 3
NCBI Official Synonym Full Names
insulin-like growth factor binding protein 3
NCBI Official Synonym Symbols
NCBI Protein Information
insulin-like growth factor-binding protein 3; IBP-3; IGFBP-3; IGF-binding protein 3; insulin-like growth factor-binding protein (IGF-BP3)
UniProt Protein Name
Insulin-like growth factor-binding protein 3
UniProt Synonym Gene Names
UniProt Entry Name
IBP3_RAT
NCBI Summary for IGFBP3
an insulin growth factor (Igf) binding protein; involved in modulating IGF-I action [RGD, Feb 2006]
UniProt Comments for IGFBP3
IGFBP3: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.
Protein type: Secreted, signal peptide; Cell development/differentiation; Secreted
Cellular Component: extracellular space; nucleus
Molecular Function: insulin-like growth factor binding; protein binding; insulin-like growth factor I binding; fibronectin binding; insulin-like growth factor II binding; protein tyrosine phosphatase activator activity
Biological Process: positive regulation of insulin-like growth factor receptor signaling pathway; positive regulation of catalytic activity; regulation of insulin-like growth factor receptor signaling pathway; positive regulation of apoptosis; negative regulation of smooth muscle cell proliferation; negative regulation of smooth muscle cell migration; protein amino acid phosphorylation; positive regulation of myoblast differentiation; osteoblast differentiation; negative regulation of cell proliferation; positive regulation of MAPKKK cascade; negative regulation of protein amino acid phosphorylation; regulation of growth; regulation of cell growth
Research Articles on IGFBP3
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with IGFBP3 elisa kit
Diseases associated with IGFBP3 elisa kit
Organs/Tissues associated with IGFBP3 elisa kit
|