NP_000590.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
30,570 Da
NCBI Official Full Name
insulin-like growth factor-binding protein 5
NCBI Official Synonym Full Names
insulin-like growth factor binding protein 5
NCBI Official Synonym Symbols
NCBI Protein Information
insulin-like growth factor-binding protein 5; IBP-5; IGFBP-5; IGF-binding protein 5
UniProt Protein Name
Insulin-like growth factor-binding protein 5
UniProt Synonym Gene Names
UniProt Entry Name
IBP5_HUMAN
UniProt Comments for IGFBP5
IGFBP5: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Protein type: Secreted, signal peptide; Secreted; Cell cycle regulation
Chromosomal Location of Human Ortholog: 2q35
Cellular Component: insulin-like growth factor binding protein complex; extracellular space; extracellular region
Molecular Function: protein binding; insulin-like growth factor I binding; fibronectin binding; insulin-like growth factor II binding
Biological Process: positive regulation of insulin-like growth factor receptor signaling pathway; mammary gland involution; hair follicle morphogenesis; negative regulation of smooth muscle cell proliferation; negative regulation of insulin-like growth factor receptor signaling pathway; glucose metabolic process; negative regulation of smooth muscle cell migration; glucose homeostasis; signal transduction; osteoblast differentiation; positive regulation of protein kinase B signaling cascade; cellular protein metabolic process; negative regulation of translation; striated muscle cell differentiation; negative regulation of osteoblast differentiation; regulation of cell growth; skeletal muscle growth; negative regulation of cell migration
Research Articles on IGFBP5
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Products associated with IGFBP5 elisa kit
Pathways associated with IGFBP5 elisa kit
Diseases associated with IGFBP5 elisa kit
Organs/Tissues associated with IGFBP5 elisa kit
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