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MRC1 elisa kit :: Chicken MRC1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2508081
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $450 +1 FREE 8GB USB
96-Strip-Wells  /  $535 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,255 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,975 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MRC1, ELISA Kit

★Popular Item★
 Also Known As   

Chicken MRC1 (Mannose Receptor C Type 1) ELISA Kit

 Product Gene Name   

MRC1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    153618
 3D Structure    ModBase 3D Structure for P22897
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 Species Reactivity    Chicken
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 Specificity    This kit recognizes natural and recombinant Chicken MRC1. No significant cross-reactivity or interference between Chicken MRC1 and analogues was observed.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    1.563-100ng/mL
 Sensitivity    Min: 0.938ng/mL; Max: 100ng/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of MRC1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for MRC1 purchase    MBS2508081 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the MRC1, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 1.563-100ng/mL in biological research samples containing MRC1, with an estimated sensitivity of Min: 0.938ng/mL; Max: 100ng/mL. The ELISA analytical biochemical technique of the MBS2508081 kit is based on MRC1 antibody-MRC1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MRC1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MRC1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for MRC1 elisa kit

   Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Chicken MRC1 concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to MRC1. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for MRC1 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain MRC1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of MRC1. You can calculate the concentration of MRC1 in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of MRC1 elisa kit    MRC1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2508081. Click to request current manual
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NCBI/Uniprot data below describe general gene information for MRC1. It may not necessarily be applicable to this product.
 NCBI GI #    4505245
 NCBI GeneID    4360
 NCBI Accession #    NP_002429.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002438.3 [Other Products]
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 UniProt Primary Accession #    P22897 [Other Products]
 UniProt Secondary Accession #    Q5VSJ2; Q5VSK2; A5PKW3 [Other Products]
 UniProt Related Accession #    P22897 [Other Products]
 Molecular Weight    56,554 Da
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 NCBI Official Full Name    macrophage mannose receptor 1
 NCBI Official Synonym Full Names    mannose receptor, C type 1
 NCBI Official Symbol    MRC1 [Similar Products]
 NCBI Official Synonym Symbols   
MMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1
[Similar Products]
 NCBI Protein Information    macrophage mannose receptor 1; C-type lectin domain family 13 member D; macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1-like 1
 UniProt Protein Name    Macrophage mannose receptor 1
 UniProt Synonym Protein Names   
C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; Macrophage mannose receptor 1-like protein 1; CD_antigen: CD206
 Protein Family    Macrophage mannose receptor
 UniProt Gene Name    MRC1 [Similar Products]
 UniProt Synonym Gene Names    CLEC13D; CLEC13DL; MRC1L1; MMR [Similar Products]
 UniProt Entry Name    MRC1_HUMAN
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 NCBI Summary for MRC1    The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Apr 2011]
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 UniProt Comments for MRC1    MRC1: Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, misc.; Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 10p12.33

Cellular Component: cell surface; integral to plasma membrane; plasma membrane; endosome membrane

Molecular Function: mannose binding; protein binding; transmembrane receptor activity; receptor activity

Biological Process: receptor-mediated endocytosis; signal transduction
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 Research Articles on MRC1    1. presence of soluble form of MR in human serum in critical illness
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with MRC1 elisa kitPathways associated with MRC1 elisa kit
 Reference Product  PubMed Publications
 CD163 elisa kit  >8 publications with MRC1 and CD163
 CHEK2 elisa kit  >3 publications with MRC1 and CHEK2
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Processing-Cross Presentation Pathway antibodies  Antigen Processing-Cross Presentation Pathway Diagram
 Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies  Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
 Cross-presentation Of Soluble Exogenous Antigens (endosomes) Pathway antibodies  Cross-presentation Of Soluble Exogenous Antigens (endosomes) Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Tuberculosis Pathway antibodies  Tuberculosis Pathway Diagram
 Tuberculosis Pathway antibodies  Tuberculosis Pathway Diagram
Diseases associated with MRC1 elisa kitOrgans/Tissues associated with MRC1 elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >20 publications with MRC1 and Nervous System Diseases
 Inflammation Antibodies  >17 publications with MRC1 and Inflammation
 Lung Diseases Antibodies  >7 publications with MRC1 and Lung Diseases
 Necrosis Antibodies  >7 publications with MRC1 and Necrosis
 Disease Models, Animal Antibodies  >3 publications with MRC1 and Disease Models, Animal
 Weight Loss Antibodies  >3 publications with MRC1 and Weight Loss
 Colitis Antibodies  >2 publications with MRC1 and Colitis
 Liver Diseases Antibodies  >1 publications with MRC1 and Liver Diseases
 Breast Neoplasms Antibodies  >1 publications with MRC1 and Breast Neoplasms
 Cognition Disorders Antibodies  >1 publications with MRC1 and Cognition Disorders
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >24 publications with MRC1 and Blood
 Brain Antibodies  >10 publications with MRC1 and Brain
 Lung Antibodies  >4 publications with MRC1 and Lung
 Connective Tissue Antibodies  >4 publications with MRC1 and Connective Tissue
 Spleen Antibodies  >4 publications with MRC1 and Spleen
 Placenta Antibodies  >1 publications with MRC1 and Placenta
 Uterus Antibodies  >1 publications with MRC1 and Uterus
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