NP_002365.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
199,526 Da
NCBI Official Full Name
microtubule-associated protein 2 isoform 1
NCBI Official Synonym Full Names
microtubule-associated protein 2
NCBI Protein Information
microtubule-associated protein 2; MAP-2
UniProt Protein Name
Microtubule-associated protein 2
UniProt Synonym Gene Names
UniProt Entry Name
MTAP2_HUMAN
NCBI Summary for MAP-2
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010]
UniProt Comments for MAP-2
MAP2: a member of the microtubule-associated protein (MAP) family. Its exact function is unknown but MAPs appear to stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. Expressed at high levels in neural tissue and the prostate. Four alternatively spliced transcript variants have been reported.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 2q34-q35
Cellular Component: microtubule; microtubule associated complex; cell soma; cytoplasm; nucleolus; dendritic shaft
Molecular Function: calmodulin binding; protein binding; microtubule binding; structural molecule activity
Biological Process: axonogenesis; dendrite morphogenesis; microtubule bundle formation; neurite development; central nervous system neuron development
Research Articles on MAP-2
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Products associated with MAP-2 elisa kit
Pathways associated with MAP-2 elisa kit
Diseases associated with MAP-2 elisa kit
Organs/Tissues associated with MAP-2 elisa kit
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