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RBP elisa kit :: Chicken Retinol Binding Protein ELISA Kit

Scan QR to view Datasheet Catalog #    MBS012136 RBP elisa kit
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Retinol Binding Protein (RBP), ELISA Kit

 Also Known As   

Chicken Retinol Binding Protein ELISA Kit

 Product Gene Name   

RBP elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 10; NC_000010.10 (48381487..48390991, complement). Location: 10q11.2
 OMIM    180290
 3D Structure    ModBase 3D Structure for P10745
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 Species Reactivity    Chicken
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of RBP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for RBP purchase    MBS012136 is a ready-to-use microwell, strip-or-full plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Retinol Binding Protein (RBP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing RBP. The ELISA analytical biochemical technique of the MBS012136 kit is based on RBP antibody-RBP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect RBP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, RBP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for RBP. It may not necessarily be applicable to this product.
 NCBI GI #    307075
 NCBI GeneID    5949
 NCBI Accession #    AAA59188.1 [Other Products]
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 UniProt Primary Accession #    P10745 [Other Products]
 UniProt Secondary Accession #    Q5VSR0 [Other Products]
 UniProt Related Accession #    P10745 [Other Products]
 Molecular Weight    135,363 Da
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 NCBI Official Full Name    retinol-binding protein
 NCBI Official Synonym Full Names    retinol binding protein 3, interstitial
 NCBI Official Symbol    RBP3 [Similar Products]
 NCBI Official Synonym Symbols   
IRBP; RBPI; RP66; D10S64; D10S65; D10S66
[Similar Products]
 NCBI Protein Information    retinol-binding protein 3; interphotoreceptor retinoid-binding protein
 UniProt Protein Name    Retinol-binding protein 3
 UniProt Synonym Protein Names   
Interphotoreceptor retinoid-binding protein; IRBP; Interstitial retinol-binding protein
 Protein Family    Receptor binding protein
 UniProt Gene Name    RBP3 [Similar Products]
 UniProt Synonym Gene Names    IRBP [Similar Products]
 UniProt Entry Name    RET3_HUMAN
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 NCBI Summary for RBP    Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process.The human IRBP gene is approximately 9.5 kbp in length and consists of four exons separated by three introns. The introns are 1.6-1.9 kbp long. The gene is transcribed by photoreceptor and retinoblastoma cells into an approximately 4.3-kilobase mRNA that is translated and processed into a glycosylated protein of 135,000 Da. The amino acid sequence of human IRBP can be divided into four contiguous homology domains with 33-38% identity, suggesting a series of gene duplication events. In the gene, the boundaries of these domains are not defined by exon-intron junctions, as might have been expected. The first three homology domains and part of the fourth are all encoded by the first large exon, which is 3,180 base pairs long. The remainder of the fourth domain is encoded in the last three exons, which are 191, 143, and approximately 740 base pairs long, respectively. [provided by RefSeq, Jul 2008]
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 UniProt Comments for RBP    RBP3: IRBP shuttles 11-cis and all trans retinoids between the retinol isomerase in the pigment epithelium and the visual pigments in the photoreceptor cells of the retina. Belongs to the peptidase S41A family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 10q11.2

Cellular Component: extracellular space; extracellular region; vesicle

Molecular Function: retinoid binding; serine-type peptidase activity; retinol binding; retinal binding

Biological Process: phototransduction, visible light; visual perception; transport; lipid metabolic process; proteolysis; retinoid metabolic process

Disease: Retinitis Pigmentosa 66; Retinitis Pigmentosa
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 Research Articles on RBP    1. Secretory defect and cytotoxicity: the potential disease mechanisms for the retinitis pigmentosa (RP)-associated interphotoreceptor retinoid-binding protein (IRBP).
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with RBP elisa kitPathways associated with RBP elisa kit
 Reference Product  PubMed Publications
 RHO elisa kit  >2 publications with RBP and RHO
 RBP2 elisa kit  >1 publications with RBP and RBP2
 OPN1SW elisa kit  >1 publications with RBP and OPN1SW
 Products by Pathway  Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Diseases Associated With Visual Transduction Pathway antibodies  Diseases Associated With Visual Transduction Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 The Canonical Retinoid Cycle In Rods (twilight Vision) Pathway antibodies  The Canonical Retinoid Cycle In Rods (twilight Vision) Pathway Diagram
 The Retinoid Cycle In Cones (daylight Vision) Pathway antibodies  The Retinoid Cycle In Cones (daylight Vision) Pathway Diagram
 Visual Phototransduction Pathway antibodies  Visual Phototransduction Pathway Diagram
 The Visual Cycle I (vertebrates) Pathway antibodies  The Visual Cycle I (vertebrates) Pathway Diagram
 The Visual Cycle I (vertebrates) Pathway antibodies  The Visual Cycle I (vertebrates) Pathway Diagram
Diseases associated with RBP elisa kitOrgans/Tissues associated with RBP elisa kit
 Disease Name  Pubmed Publications
 Hyperplasia Antibodies  >3 publications with RBP and Hyperplasia
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >12 publications with RBP and Eye
 Blood Antibodies  >2 publications with RBP and Blood
 Muscle Antibodies  >1 publications with RBP and Muscle
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