AAC51861.1
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
46,800 Da
NCBI Official Full Name
SCCL vasopressin subtype 1a receptor
NCBI Official Synonym Full Names
arginine vasopressin receptor 1A
NCBI Protein Information
vasopressin V1a receptor; V1a vasopressin receptor; antidiuretic hormone receptor 1A; SCCL vasopressin subtype 1a receptor; V1-vascular vasopressin receptor AVPR1A; vascular/hepatic-type arginine vasopressin receptor
UniProt Protein Name
Vasopressin V1a receptor
UniProt Synonym Protein Names
AVPR V1a; Antidiuretic hormone receptor 1a; Vascular/hepatic-type arginine vasopressin receptor
UniProt Synonym Gene Names
UniProt Entry Name
V1AR_HUMAN
NCBI Summary for SCC
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. [provided by RefSeq, Jul 2008]
UniProt Comments for SCC
AVPR1A: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
Protein type: GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR
Chromosomal Location of Human Ortholog: 12q14-q15
Cellular Component: integral to plasma membrane; plasma membrane; cytoplasmic vesicle; endosome
Molecular Function: protein binding; protein kinase C binding; V1A vasopressin receptor binding; peptide hormone binding; peptide binding; vasopressin receptor activity
Biological Process: blood circulation; positive regulation of cellular pH reduction; positive regulation of glutamate secretion; positive regulation of systemic arterial blood pressure; cellular response to water deprivation; elevation of cytosolic calcium ion concentration; positive regulation of cell proliferation; response to corticosterone stimulus; penile erection; positive regulation of prostaglandin biosynthetic process; grooming behavior; generation of precursor metabolites and energy; maternal behavior; calcium-mediated signaling; myotube differentiation; positive regulation of heart rate; social behavior; positive regulation of cell growth; cellular response to hormone stimulus; negative regulation of female receptivity; G-protein coupled receptor protein signaling pathway; telencephalon development; regulation of systemic arterial blood pressure by vasopressin; negative regulation of transmission of nerve impulse; phospholipase C activation; positive regulation of vasoconstriction; sperm ejaculation
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Organs/Tissues associated with SCC elisa kit
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