BAA24499.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
149,876 Da
NCBI Official Full Name
sFlt-1
NCBI Official Synonym Full Names
FMS-like tyrosine kinase 1
NCBI Official Synonym Symbols
Flt-1; sFlt1; VEGFR1; VEGFR-1; AI323757 [Similar Products]
NCBI Protein Information
vascular endothelial growth factor receptor 1; embryonic receptor kinase 2; tyrosine-protein kinase receptor FLT; vascular permeability factor receptor; vascular endothelial growth factor receptor-1
UniProt Protein Name
Vascular endothelial growth factor receptor 1
UniProt Synonym Protein Names
Embryonic receptor kinase 2; Fms-like tyrosine kinase 1; FLT-1; Tyrosine-protein kinase receptor FLT
UniProt Synonym Gene Names
UniProt Entry Name
VGFR1_MOUSE
UniProt Comments for SFLT-1
VEGFR1: a receptor tyrosine kinase of the VEGFR family. Receptor for VEGF, VEGFB and PGF. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Two splice variant isoforms have been described. Isoform SFlt1 may have an inhibitory role in angiogenesis.
Protein type: Membrane protein, integral; Kinase, protein; Protein kinase, tyrosine (receptor); EC 2.7.10.1; Protein kinase, TK; TK group; VEGFR family
Cellular Component: focal adhesion; membrane; integral to plasma membrane; plasma membrane; integral to membrane; endosome; receptor complex
Molecular Function: transferase activity; identical protein binding; vascular endothelial growth factor receptor activity; growth factor binding; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; transmembrane receptor protein tyrosine kinase activity; kinase activity; ATP binding; protein kinase activity
Biological Process: cell migration; peptidyl-tyrosine phosphorylation; multicellular organismal development; protein amino acid autophosphorylation; positive regulation of phosphoinositide 3-kinase activity; chemotaxis; protein amino acid phosphorylation; positive regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of phosphoinositide 3-kinase cascade; patterning of blood vessels; positive regulation of MAP kinase activity; monocyte chemotaxis; positive regulation of angiogenesis; positive regulation of MAPKKK cascade; response to hypoxia; blood vessel morphogenesis; embryonic morphogenesis; sprouting angiogenesis; angiogenesis; vascular endothelial growth factor receptor signaling pathway; cell differentiation; phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway; positive regulation of cell migration
Research Articles on SFLT-1
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Pathways associated with SFLT-1 elisa kit
Diseases associated with SFLT-1 elisa kit
Organs/Tissues associated with SFLT-1 elisa kit
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