Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow ELISA Kit rightarrow alpha-SYN rightarrow Chicken alpha-SYN  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Influenza-A Hemagglutinin H3N2 Antibody
 • NIN1-RPN12 binding protein 1 homolog (S. cerevisiae) (NOB1) ELISA Kit
 • GSK-3b Antibody
 • CD244 Antibody
 • TET2 Antibody
 • lipoprotein lipase (LPL) ELISA Kit
 • Kv10.2 (KCNH5) Antibody
 • GREM1 Blocking Peptide
 • Mesothelin (MSLN) ELISA Kit
 • Dopamine Receptor D3 (Drd3) Antibody
 • Secretory Leukocyte Peptidase Inhibitor (SLPI) ELISA Kit
 • Actin, alpha cardiac muscle 1 (ACTC1) ELISA Kit
 • NEL-like protein 1 (Nell1) Antibody
 • Calcium-calmodulin-dependen t protein kinase type II subunit ... Recombinant Protein
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

alpha-SYN elisa kit :: Chicken Synuclein Alpha (alpha-SYN) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS264409 alpha-SYN elisa kit
Unit / Price
48-Strip-Wells  /  $315 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,825 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,425 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Synuclein Alpha (alpha-SYN), ELISA Kit

 Also Known As   

Chicken Synuclein Alpha (alpha-SYN) ELISA Kit

 Product Synonym Names    Chicken Synuclein Alpha (a-SYN) ELISA Kit
 Product Gene Name   

alpha-SYN elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Request for Manual Insert    Request Manual
 OMIM    605543
Section Bar
 Species Reactivity    Chicken
Section Bar
Section Bar
 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of alpha-SYN elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for alpha-SYN purchase    MBS264409 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Synuclein Alpha (alpha-SYN) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing alpha-SYN. The ELISA analytical biochemical technique of the MBS264409 kit is based on alpha-SYN antibody-alpha-SYN antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect alpha-SYN antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, alpha-SYN. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for alpha-SYN. It may not necessarily be applicable to this product.
 NCBI GI #    16356657
 NCBI GeneID    6622
 NCBI Accession #    AAL15443.1 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q13701; Q4JHI3; Q6IAU6; A8K2A4 [Other Products]
 UniProt Related Accession #    P37840 [Other Products]
 Molecular Weight    13,109 Da
Table BarTOPTable Bar
 NCBI Official Full Name    synuclein alpha
 NCBI Official Synonym Full Names    synuclein, alpha (non A4 component of amyloid precursor)
 NCBI Official Symbol    SNCA [Similar Products]
 NCBI Official Synonym Symbols   
PD1; NACP; PARK1; PARK4
[Similar Products]
 NCBI Protein Information    alpha-synuclein; synuclein alpha-140; non A-beta component of AD amyloid
 UniProt Protein Name    Alpha-synuclein
 UniProt Synonym Protein Names   
Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP
 UniProt Gene Name    SNCA [Similar Products]
 UniProt Synonym Gene Names    NACP; PARK1; NACP [Similar Products]
 UniProt Entry Name    SYUA_HUMAN
Section Bar
 NCBI Summary for alpha-SYN    Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009]
Section Bar
 UniProt Comments for alpha-SYN    SNCA: a member of the synuclein family. Abundantly expressed in the brain. Inhibits phospholipase D2 selectively. May integrate presynaptic signaling and membrane trafficking. Implicated in the pathogenesis of Parkinson's disease. A major component of amyloid plaques in the brains of patients with Alzheimer's disease. Two alternatively spliced isoforms transcripts have been identified.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 4q21

Cellular Component: Golgi apparatus; nuclear outer membrane; rough endoplasmic reticulum; mitochondrion; lysosome; extracellular region; fibril; terminal button; cell cortex; inclusion body; mitochondrial respiratory chain complex I; cytosol; actin cytoskeleton; synaptic vesicle; platelet alpha granule membrane; growth cone; perinuclear region of cytoplasm; axon; cytoplasm; plasma membrane; ribosome; nucleus; cell junction

Molecular Function: protein domain specific binding; identical protein binding; zinc ion binding; histone binding; kinesin binding; ferrous iron binding; microtubule binding; caspase inhibitor activity; magnesium ion binding; beta-tubulin binding; protein N-terminus binding; phosphoprotein binding; Hsp70 protein binding; oxidoreductase activity; calcium ion binding; dynein binding; protein binding; phospholipase binding; copper ion binding; phospholipid binding; fatty acid binding; tau protein binding; alpha-tubulin binding

Biological Process: regulation of acyl-CoA biosynthetic process; positive regulation of apoptosis; adult locomotory behavior; response to lipopolysaccharide; positive regulation of endocytosis; dopamine biosynthetic process; positive regulation of neurotransmitter secretion; calcium ion homeostasis; response to magnesium ion; synapse organization and biogenesis; fibril organization and biogenesis; dopamine uptake; negative regulation of neuron apoptosis; response to drug; negative regulation of dopamine metabolic process; synaptic vesicle endocytosis; negative regulation of transporter activity; negative regulation of apoptosis; regulation of long-term neuronal synaptic plasticity; negative regulation of serotonin uptake; mitochondrial membrane organization and biogenesis; negative regulation of norepinephrine uptake; microglial cell activation; negative regulation of caspase activity; negative regulation of monooxygenase activity; negative regulation of transcription from RNA polymerase II promoter; fatty acid metabolic process; regulation of dopamine secretion; negative regulation of dopamine uptake; negative regulation of histone acetylation; negative regulation of exocytosis; negative regulation of protein amino acid phosphorylation; behavioral response to cocaine; receptor internalization; phospholipid metabolic process; response to iron(II) ion; positive regulation of receptor recycling; aging; caspase activation; neutral lipid metabolic process; protein destabilization; regulation of glutamate secretion; regulation of macrophage activation; negative regulation of microtubule polymerization; positive regulation of peptidyl-serine phosphorylation; organelle ATP synthesis coupled electron transport; regulation of locomotion; positive regulation of release of sequestered calcium ion into cytosol; regulation of excitatory postsynaptic membrane potential

Disease: Parkinson Disease 4, Autosomal Dominant; Dementia, Lewy Body; Parkinson Disease 1, Autosomal Dominant
Table BarTOPTable Bar
 Research Articles on alpha-SYN    1. The successful detection of multiple electron paramagnetic resonance distances combined with the pair-labeling strategy presented in this study provided a considerable number of long-range constrains at the molecular level on the fold of SNCA in fibrils.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with alpha-SYN elisa kitPathways associated with alpha-SYN elisa kit
 Reference Product  PubMed Publications
 LRRK2 elisa kit  >113 publications with alpha-SYN and LRRK2
 PARK7 elisa kit  >49 publications with alpha-SYN and PARK7
 SNCAIP elisa kit  >31 publications with alpha-SYN and SNCAIP
 PARK2 elisa kit  >30 publications with alpha-SYN and PARK2
 SLC6A3 elisa kit  >12 publications with alpha-SYN and SLC6A3
 BAD elisa kit  >3 publications with alpha-SYN and BAD
 FYN elisa kit  >2 publications with alpha-SYN and FYN
 STUB1 elisa kit  >1 publications with alpha-SYN and STUB1
 Products by Pathway  Pathway Diagram
 Alpha-synuclein Signaling Pathway antibodies  Alpha-synuclein Signaling Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimers Disease Pathway antibodies  Alzheimers Disease Pathway Diagram
 Amyloids Pathway antibodies  Amyloids Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
 Parkin-Ubiquitin Proteasomal System Pathway antibodies  Parkin-Ubiquitin Proteasomal System Pathway Diagram
 Parkinson's Disease Pathway antibodies  Parkinson's Disease Pathway Diagram
 Parkinsons Disease Pathway antibodies  Parkinsons Disease Pathway Diagram
Diseases associated with alpha-SYN elisa kitOrgans/Tissues associated with alpha-SYN elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >1054 publications with alpha-SYN and Nervous System Diseases
 Brain Diseases Antibodies  >1034 publications with alpha-SYN and Brain Diseases
 Neurodegenerative Diseases Antibodies  >1021 publications with alpha-SYN and Neurodegenerative Diseases
 Movement Disorders Antibodies  >901 publications with alpha-SYN and Movement Disorders
 Parkinsonian Disorders Antibodies  >833 publications with alpha-SYN and Parkinsonian Disorders
 Parkinson Disease Antibodies  >766 publications with alpha-SYN and Parkinson Disease
 Lewy Body Disease Antibodies  >271 publications with alpha-SYN and Lewy Body Disease
 Nerve Degeneration Antibodies  >162 publications with alpha-SYN and Nerve Degeneration
 Disease Models, Animal Antibodies  >127 publications with alpha-SYN and Disease Models, Animal
 Drug Toxicity Antibodies  >71 publications with alpha-SYN and Drug Toxicity
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >989 publications with alpha-SYN and Nerve
 Brain Antibodies  >723 publications with alpha-SYN and Brain
 Blood Antibodies  >54 publications with alpha-SYN and Blood
 Embryonic Tissue Antibodies  >28 publications with alpha-SYN and Embryonic Tissue
 Kidney Antibodies  >19 publications with alpha-SYN and Kidney
 Heart Antibodies  >9 publications with alpha-SYN and Heart
 Eye Antibodies  >9 publications with alpha-SYN and Eye
 Skin Antibodies  >6 publications with alpha-SYN and Skin
 Bone Antibodies  >6 publications with alpha-SYN and Bone
 Liver Antibodies  >6 publications with alpha-SYN and Liver
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions