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TCF20 elisa kit :: Chicken Transcription Factor 20 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS008108 TCF20 elisa kit
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 Product Name   

Transcription Factor 20 (TCF20), ELISA Kit

 Also Known As   

Chicken Transcription Factor 20 ELISA Kit

 Product Gene Name   

TCF20 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 22; NC_000022.10 (42556019..42611445, complement). Location: 22q13.3; 22q13.3
 OMIM    603107
 3D Structure    ModBase 3D Structure for Q9UGU0
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 Species Reactivity    Chicken
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TCF20 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TCF20 purchase    MBS008108 is a ready-to-use microwell, strip-or-full plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Transcription Factor 20 (TCF20) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TCF20. The ELISA analytical biochemical technique of the MBS008108 kit is based on TCF20 antibody-TCF20 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TCF20 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TCF20. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for TCF20. It may not necessarily be applicable to this product.
 NCBI GI #    31652244
 NCBI GeneID    6942
 NCBI Accession #    NP_005641.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005650.2 [Other Products]
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 UniProt Primary Accession #    Q9UGU0 [Other Products]
 UniProt Secondary Accession #    O14528; Q13078; Q4V353; Q9H4M0; A9JX12 [Other Products]
 UniProt Related Accession #    Q9UGU0 [Other Products]
 Molecular Weight    211,771 Da
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 NCBI Official Full Name    transcription factor 20 isoform 1
 NCBI Official Synonym Full Names    transcription factor 20 (AR1)
 NCBI Official Symbol    TCF20 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    transcription factor 20; nuclear factor SPBP; SPRE-binding protein; stromelysin-1 PDGF-responsive element-binding protein; stromelysin-1 platelet-derived growth factor-responsive element binding protein
 UniProt Protein Name    Transcription factor 20
 UniProt Synonym Protein Names   
Nuclear factor SPBP; Protein AR1; Stromelysin-1 PDGF-responsive element-binding protein
 Protein Family    Transcription factor
 UniProt Gene Name    TCF20 [Similar Products]
 UniProt Synonym Gene Names    KIAA0292; SPBP; TCF-20 [Similar Products]
 UniProt Entry Name    TCF20_HUMAN
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 NCBI Summary for TCF20    This gene encodes a transcription factor that recognizes the platelet-derived growth factor-responsive element in the matrix metalloproteinase 3 promoter. The encoded protein is thought to be a transcriptional coactivator, enhancing the activity of transcription factors such as JUN and SP1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
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 UniProt Comments for TCF20    TCF20: a transcriptional activator. Binds to the regulatory region of MMP3 and thereby controls stromelysin expression. It stimulates the activity of various transcriptional activators such as JUN, SP1, PAX6 and ETS1, suggesting a function as a coactivator. Two alternatively spliced isoforms have been described. Isoform 1 is exclusively expressed in brain, heart and testis, and predominates in liver and kidney. Isoform 2 predominates in lung.

Protein type: Nuclear receptor co-regulator; DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 22q13.3|22q13.3

Cellular Component: nucleoplasm; nucleus

Molecular Function: DNA binding; zinc ion binding; transcription coactivator activity

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent
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 Research Articles on TCF20    1. Study has identified SPBP as a transcriptional coactivator of AR. We also show that Pax6 inhibits SPBP-mediated enhancement of AR activity on the AR target gene probasin promoter, a repression that was partly reversed by increased expression of SPBP.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TCF20 elisa kitPathways associated with TCF20 elisa kit
 Reference Product  PubMed Publications
 MMP3 elisa kit  >1 publications with TCF20 and MMP3
 RNF4 elisa kit  >1 publications with TCF20 and RNF4
 JUN elisa kit  >1 publications with TCF20 and JUN
 TOPBP1 elisa kit  >1 publications with TCF20 and TOPBP1
 Products by Pathway  Pathway Diagram
 Matrix Metalloproteinases Pathway antibodies  Matrix Metalloproteinases Pathway Diagram
Diseases associated with TCF20 elisa kitOrgans/Tissues associated with TCF20 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with TCF20 and Neoplasms
 Fibrosis Antibodies  >1 publications with TCF20 and Fibrosis
 Inflammation Antibodies  >1 publications with TCF20 and Inflammation
 Necrosis Antibodies  >1 publications with TCF20 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >2 publications with TCF20 and Prostate
 Eye Antibodies  >1 publications with TCF20 and Eye
 Ovary Antibodies  >1 publications with TCF20 and Ovary
 Lung Antibodies  >1 publications with TCF20 and Lung
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