NP_061986.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
22,300 Da
NCBI Official Full Name
fibroblast growth factor 21
NCBI Official Synonym Full Names
fibroblast growth factor 21
NCBI Protein Information
fibroblast growth factor 21; FGF-21
UniProt Protein Name
Fibroblast growth factor 21
UniProt Synonym Gene Names
UniProt Entry Name
FGF21_HUMAN
NCBI Summary for FGF-21
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this growth factor has not yet been determined. [provided by RefSeq, Jul 2008]
UniProt Comments for FGF-21
FGF21: Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. Belongs to the heparin-binding growth factors family.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 19q13.33
Cellular Component: extracellular region
Molecular Function: protein binding; growth factor activity; fibroblast growth factor receptor binding
Biological Process: positive regulation of glucose import; cell-cell signaling; positive regulation of cell proliferation; positive regulation of low-density lipoprotein receptor biosynthetic process; signal transduction
Research Articles on FGF-21
Precautions
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Products associated with FGF-21 elisa kit
Pathways associated with FGF-21 elisa kit
Diseases associated with FGF-21 elisa kit
Organs/Tissues associated with FGF-21 elisa kit
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