NP_000151.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
54,009 Da
NCBI Official Full Name
glucagon receptor
NCBI Official Synonym Full Names
glucagon receptor
NCBI Official Synonym Symbols
NCBI Protein Information
glucagon receptor
UniProt Protein Name
Glucagon receptor
UniProt Synonym Gene Names
UniProt Entry Name
GLR_HUMAN
NCBI Summary for GCGR
The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).[provided by RefSeq, Jan 2010]
UniProt Comments for GCGR
GCGR: This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 2 family.
Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 2; Membrane protein, integral
Chromosomal Location of Human Ortholog: 17q25
Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane
Molecular Function: glucagon receptor activity; guanyl-nucleotide exchange factor activity
Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; generation of precursor metabolites and energy; glucose homeostasis; regulation of blood pressure; response to nutrient; response to starvation
Disease: Diabetes Mellitus, Noninsulin-dependent
Research Articles on GCGR
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Pathways associated with GCGR elisa kit
Diseases associated with GCGR elisa kit
Organs/Tissues associated with GCGR elisa kit
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