NP_647538.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
158,537 Da
NCBI Official Full Name
attractin isoform 2 preproprotein
NCBI Official Synonym Full Names
attractin
NCBI Official Synonym Symbols
NCBI Protein Information
attractin; attractin-2; mahogany homolog; mahogany protein
UniProt Protein Name
Attractin
UniProt Synonym Protein Names
DPPT-L; Mahogany homolog
UniProt Synonym Gene Names
UniProt Entry Name
ATRN_HUMAN
NCBI Summary for ATRN
Multiple transcript variants encoding different isoforms exist for this gene. One of the isoforms is a membrane-bound protein with sequence similarity to the mouse mahogany protein, a receptor involved in controlling obesity. The other two isoforms are secreted proteins involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines. [provided by RefSeq, May 2011]
UniProt Comments for ATRN
ATRN: Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti. Has a critical role in normal myelination in the central nervous system. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 20p13
Cellular Component: extracellular space; integral to plasma membrane; cytoplasm; plasma membrane
Molecular Function: receptor activity; carbohydrate binding
Biological Process: myelination; pigmentation; cerebellum development; regulation of multicellular organism growth; response to oxidative stress; inflammatory response
Research Articles on ATRN
Precautions
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Disclaimer
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Diseases associated with ATRN elisa kit
Organs/Tissues associated with ATRN elisa kit
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