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COL8A1 elisa kit :: Fish Collagen Type VIII Alpha 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS014493 COL8A1 elisa kit
Unit / Price
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Collagen Type VIII Alpha 1 (COL8A1), ELISA Kit

 Also Known As   

Fish Collagen Type VIII Alpha 1 ELISA Kit

 Product Gene Name   

COL8A1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 3; NC_000003.11 (99357440..99515577). Location: 3q12.3
 OMIM    120251
 3D Structure    ModBase 3D Structure for P27658
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 Species Reactivity    Fish
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of COL8A1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for COL8A1 purchase    MBS014493 is a ready-to-use microwell, strip-or-full plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Collagen Type VIII Alpha 1 (COL8A1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing COL8A1. The ELISA analytical biochemical technique of the MBS014493 kit is based on COL8A1 antibody-COL8A1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect COL8A1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, COL8A1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for COL8A1. It may not necessarily be applicable to this product.
 NCBI GI #    32895368
 NCBI GeneID    1295
 NCBI Accession #    NP_065084.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_020351.3 [Other Products]
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 UniProt Primary Accession #    P27658 [Other Products]
 UniProt Secondary Accession #    Q53XI6; Q96D07; D3DN42 [Other Products]
 UniProt Related Accession #    P27658 [Other Products]
 Molecular Weight    73,364 Da
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 NCBI Official Full Name    collagen alpha-1(VIII) chain
 NCBI Official Synonym Full Names    collagen, type VIII, alpha 1
 NCBI Official Symbol    COL8A1 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    collagen alpha-1(VIII) chain; collagen alpha-1(VIII) chain; endothelial collagen; collagen VIII, alpha-1 polypeptide; cell proliferation-inducing protein 41; smooth muscle cell-expressed and macrophage conditioned medium-induced protein smag-64
 UniProt Protein Name    Collagen alpha-1(VIII) chain
 UniProt Synonym Protein Names   
Endothelial collagen
 Protein Family    Collagen
 UniProt Gene Name    COL8A1 [Similar Products]
 UniProt Synonym Gene Names    C3orf7 [Similar Products]
 UniProt Entry Name    CO8A1_HUMAN
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 NCBI Summary for COL8A1    This gene encodes one of the two alpha chains of type VIII collagen. The gene product is a short chain collagen and a major component of the basement membrane of the corneal endothelium. The type VIII collagen fibril can be either a homo- or a heterotrimer. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Dec 2011]
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 UniProt Comments for COL8A1    COL8A1: Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis.

Protein type: Secreted, signal peptide; Extracellular matrix; Secreted

Chromosomal Location of Human Ortholog: 3q12.3

Cellular Component: extracellular matrix; intracellular membrane-bound organelle; endoplasmic reticulum lumen; extracellular region; collagen type VIII

Biological Process: collagen catabolic process; extracellular matrix disassembly; epithelial cell proliferation; extracellular matrix organization and biogenesis; camera-type eye morphogenesis; angiogenesis; cell adhesion
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 Research Articles on COL8A1    1. The purpose of this study is to evaluate COL8A1 and COL8A2 as candidate genes for thin central corneal thickness in human primary open angle glaucoma patients.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with COL8A1 elisa kitPathways associated with COL8A1 elisa kit
 Reference Product  PubMed Publications
 COL8A2 elisa kit  >10 publications with COL8A1 and COL8A2
 COL4A1 elisa kit  >1 publications with COL8A1 and COL4A1
 COL12A1 elisa kit  >1 publications with COL8A1 and COL12A1
 COL11A1 elisa kit  >1 publications with COL8A1 and COL11A1
 COL3A1 elisa kit  >1 publications with COL8A1 and COL3A1
 COL1A1 elisa kit  >1 publications with COL8A1 and COL1A1
 Products by Pathway  Pathway Diagram
 Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway antibodies  Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway Diagram
 Collagen Biosynthesis And Modifying Enzymes Pathway antibodies  Collagen Biosynthesis And Modifying Enzymes Pathway Diagram
 Collagen Formation Pathway antibodies  Collagen Formation Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
Diseases associated with COL8A1 elisa kitOrgans/Tissues associated with COL8A1 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with COL8A1 and Neoplasms
 Carcinoma Antibodies  >3 publications with COL8A1 and Carcinoma
 Kidney Diseases Antibodies  >3 publications with COL8A1 and Kidney Diseases
 Fibrosis Antibodies  >2 publications with COL8A1 and Fibrosis
 Liver Neoplasms Antibodies  >2 publications with COL8A1 and Liver Neoplasms
 Disease Models, Animal Antibodies  >2 publications with COL8A1 and Disease Models, Animal
 Liver Diseases Antibodies  >2 publications with COL8A1 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >2 publications with COL8A1 and Carcinoma, Hepatocellular
 Congenital Abnormalities Antibodies  >2 publications with COL8A1 and Congenital Abnormalities
 Drug Toxicity Antibodies  >1 publications with COL8A1 and Drug Toxicity
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >7 publications with COL8A1 and Eye
 Kidney Antibodies  >5 publications with COL8A1 and Kidney
 Vascular Antibodies  >4 publications with COL8A1 and Vascular
 Bone Antibodies  >1 publications with COL8A1 and Bone
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