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HB-AGE elisa kit :: Fish Hemoglobin-Advanced Glycosylation End Products ELISA Kit

Scan QR to view Datasheet Catalog #    MBS009525 HB-AGE elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Hemoglobin-Advanced Glycosylation End Products (HB-AGE), ELISA Kit

★Popular Item★
 Also Known As   

Fish Hemoglobin-Advanced Glycosylation End Products ELISA Kit

 Product Gene Name   

HB-AGE elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    142250
 3D Structure    ModBase 3D Structure for P69892
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 Species Reactivity    Fish
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Body fluids, tissue homogenates, secretions or feces samples
 Assay Type    Quantitative Sandwich
 Detection Range    31.2 ng/ml - 1000 ng/ml
 Sensitivity    5.0 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of HB-AGE elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for HB-AGE purchase    MBS009525 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Hemoglobin-Advanced Glycosylation End Products (HB-AGE) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 31.2 ng/ml - 1000 ng/ml in biological research samples containing HB-AGE, with an estimated sensitivity of 5.0 ng/ml. The ELISA analytical biochemical technique of the MBS009525 kit is based on HB-AGE antibody-HB-AGE antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HB-AGE antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HB-AGE. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Body fluids, tissue homogenates, secretions or feces samples. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for HB-AGE elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of HB-AGE (hereafter termed "analyte") in undiluted original Fish body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS009525. Click to request current manual
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NCBI/Uniprot data below describe general gene information for HB-AGE. It may not necessarily be applicable to this product.
 NCBI GI #    56749861
 NCBI GeneID    3048
 NCBI Accession #    P69892.2 [Other Products]
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 UniProt Primary Accession #    P69892 [Other Products]
 UniProt Secondary Accession #    P02096; P62027; Q14491; Q68NH9; Q96FH6; Q96FH7; A8MZE0 [Other Products]
 UniProt Related Accession #    P69892 [Other Products]
 Molecular Weight    16,126 Da
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 NCBI Official Full Name    Hemoglobin subunit gamma-2
 NCBI Official Synonym Full Names    hemoglobin, gamma G
 NCBI Official Symbol    HBG2 [Similar Products]
 NCBI Official Synonym Symbols   
TNCY; HBG-T1
[Similar Products]
 NCBI Protein Information    hemoglobin subunit gamma-2; hb F Ggamma; methemoglobin; gamma-2-globin; abnormal hemoglobin; G-gamma globin Paulinia; hemoglobin gamma-2 chain; hemoglobin gamma-G chain
 UniProt Protein Name    Hemoglobin subunit gamma-2
 UniProt Synonym Protein Names   
Gamma-2-globin; Hb F Ggamma; Hemoglobin gamma-2 chain; Hemoglobin gamma-G chain
 UniProt Gene Name    HBG2 [Similar Products]
 UniProt Entry Name    HBG2_HUMAN
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 NCBI Summary for HB-AGE    The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]
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 UniProt Comments for HB-AGE    HBG2: Gamma chains make up the fetal hemoglobin F, in combination with alpha chains. Defects in HBG2 are the cause of cyanosis transient neonatal (TNCY). TNCY is a disorder characterized by cyanosis in the fetus and neonate, due to a defect in the fetal hemoglobin chain which has reduced affinity for oxygen. Some patients develop anemia resulting from increased destruction of red cells containing abnormal or unstable hemoglobin. The cyanosis resolves spontaneously by 5 to 6 months of age or earlier, as the adult beta-globin chain is produced and replaces the fetal gamma- globin chain. Belongs to the globin family.

Protein type: Carrier

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: hemoglobin complex; cytosol

Molecular Function: iron ion binding; heme binding; oxygen binding; oxygen transporter activity

Biological Process: oxygen transport; blood coagulation

Disease: Cyanosis, Transient Neonatal; Fetal Hemoglobin Quantitative Trait Locus 1
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 Research Articles on HB-AGE    1. Data suggest that segregation of BCL11A haplotype 2 indicating an involvement of this locus in Hb F expression.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with HB-AGE elisa kitPathways associated with HB-AGE elisa kit
 Reference Product  PubMed Publications
 HBG1 elisa kit  >20 publications with HB-AGE and HBG1
 HBB elisa kit  >13 publications with HB-AGE and HBB
 BCL11A elisa kit  >11 publications with HB-AGE and BCL11A
 HBA2 elisa kit  >5 publications with HB-AGE and HBA2
 KLF1 elisa kit  >1 publications with HB-AGE and KLF1
 Products by Pathway  Pathway Diagram
 Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies  Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
Diseases associated with HB-AGE elisa kitOrgans/Tissues associated with HB-AGE elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >2 publications with HB-AGE and Neoplasms
 Nervous System Diseases Antibodies  >2 publications with HB-AGE and Nervous System Diseases
 Pain Antibodies  >1 publications with HB-AGE and Pain
 Central Nervous System Diseases Antibodies  >1 publications with HB-AGE and Central Nervous System Diseases
 Skin Diseases Antibodies  >1 publications with HB-AGE and Skin Diseases
 Brain Diseases Antibodies  >1 publications with HB-AGE and Brain Diseases
 Neoplasms, Experimental Antibodies  >1 publications with HB-AGE and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >24 publications with HB-AGE and Blood
 Vascular Antibodies  >2 publications with HB-AGE and Vascular
 Bone Antibodies  >2 publications with HB-AGE and Bone
 Brain Antibodies  >2 publications with HB-AGE and Brain
 Bone Marrow Antibodies  >1 publications with HB-AGE and Bone Marrow
 Embryonic Tissue Antibodies  >1 publications with HB-AGE and Embryonic Tissue
 Liver Antibodies  >1 publications with HB-AGE and Liver
 Heart Antibodies  >1 publications with HB-AGE and Heart
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