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IGFBP3 elisa kit :: Fish Insulin Like Growth Factor Binding Protein 3 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS017580 IGFBP3 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Insulin Like Growth Factor Binding Protein 3 (IGFBP3), ELISA Kit

★Popular Item★
 Also Known As   

Fish Insulin Like Growth Factor Binding Protein 3 ELISA Kit

 Product Gene Name   

IGFBP3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 7; NC_000007.13 (45951844..45960871, complement). Location: 7p13-p12
 OMIM    146732
 3D Structure    ModBase 3D Structure for P17936
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 Species Reactivity    Fish
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Undiluted original Fish body fluids, tissue homogenates, secretions or feces samples.
 Assay Type    Sandwich (Quantitative)
 Detection Range    31.2 ng/ml - 1000 ng/ml.
 Sensitivity    5.0 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IGFBP3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IGFBP3 purchase    MBS017580 is a ready-to-use microwell, strip plate Sandwich (Quantitative) ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Insulin Like Growth Factor Binding Protein 3 (IGFBP3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 31.2 ng/ml - 1000 ng/ml in biological research samples containing IGFBP3, with an estimated sensitivity of 5.0 ng/ml. The ELISA analytical biochemical technique of the MBS017580 kit is based on IGFBP3 antibody-IGFBP3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IGFBP3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IGFBP3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Undiluted original Fish body fluids, tissue homogenates, secretions or feces samples. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for IGFBP3 elisa kit

   Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of IGFBP3 (hereafter termed "analyte") in undiluted original Fish body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS017580. Click to request current manual
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NCBI/Uniprot data below describe general gene information for IGFBP3. It may not necessarily be applicable to this product.
 NCBI GI #    62243248
 NCBI GeneID    3486
 NCBI Accession #    NP_001013416.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001013398.1 [Other Products]
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 UniProt Primary Accession #    P17936 [Other Products]
 UniProt Secondary Accession #    Q2V509; Q6P1M6; Q9UCL4; A4D2F5; D3DVM0 [Other Products]
 UniProt Related Accession #    P17936 [Other Products]
 Molecular Weight    31,674 Da
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 NCBI Official Full Name    insulin-like growth factor-binding protein 3 isoform a
 NCBI Official Synonym Full Names    insulin-like growth factor binding protein 3
 NCBI Official Symbol    IGFBP3 [Similar Products]
 NCBI Official Synonym Symbols   
IBP3; BP-53
[Similar Products]
 NCBI Protein Information    insulin-like growth factor-binding protein 3; IBP-3; IGFBP-3; binding protein 29; binding protein 53; IGF-binding protein 3; growth hormone-dependent binding protein; acid stable subunit of the 140 K IGF complex
 UniProt Protein Name    Insulin-like growth factor-binding protein 3
 Protein Family    Insulin-like growth factor-binding protein
 UniProt Gene Name    IGFBP3 [Similar Products]
 UniProt Synonym Gene Names    IBP3; IBP-3; IGF-binding protein 3; IGFBP-3 [Similar Products]
 UniProt Entry Name    IBP3_HUMAN
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 NCBI Summary for IGFBP3    This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
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 UniProt Comments for IGFBP3    IGFBP3: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.

Protein type: Secreted; Secreted, signal peptide; Cell development/differentiation

Chromosomal Location of Human Ortholog: 7p12.3

Cellular Component: insulin-like growth factor binding protein complex; extracellular space; extracellular region; nucleus

Molecular Function: insulin-like growth factor binding; protein binding; insulin-like growth factor I binding; fibronectin binding; metal ion binding; insulin-like growth factor II binding; protein tyrosine phosphatase activator activity

Biological Process: positive regulation of catalytic activity; positive regulation of insulin-like growth factor receptor signaling pathway; regulation of insulin-like growth factor receptor signaling pathway; positive regulation of apoptosis; apoptosis; negative regulation of smooth muscle cell proliferation; negative regulation of smooth muscle cell migration; protein amino acid phosphorylation; positive regulation of myoblast differentiation; negative regulation of signal transduction; osteoblast differentiation; negative regulation of cell proliferation; cellular protein metabolic process; negative regulation of protein amino acid phosphorylation; positive regulation of MAPKKK cascade; regulation of cell growth
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 Research Articles on IGFBP3    1. In patients with esophageal squamous cell carcinoma, reduced IGFBP-3 expression may be a risk factor for advanced clinicopathological classification and poor patient survival.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IGFBP3 elisa kitPathways associated with IGFBP3 elisa kit
 Reference Product  PubMed Publications
 IGF1 elisa kit  >175 publications with IGFBP3 and IGF1
 IGF2 elisa kit  >63 publications with IGFBP3 and IGF2
 IGFALS elisa kit  >16 publications with IGFBP3 and IGFALS
 TP53 elisa kit  >9 publications with IGFBP3 and TP53
 MMP2 elisa kit  >5 publications with IGFBP3 and MMP2
 ADAM12 elisa kit  >1 publications with IGFBP3 and ADAM12
 FN1 elisa kit  >1 publications with IGFBP3 and FN1
 Products by Pathway  Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram
 Integrated Pancreatic Cancer Pathway antibodies  Integrated Pancreatic Cancer Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Myometrial Relaxation And Contraction Pathways antibodies  Myometrial Relaxation And Contraction Pathways Diagram
 Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway antibodies  Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway Diagram
 Senescence And Autophagy Pathway antibodies  Senescence And Autophagy Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 P53 Signaling Pathway antibodies  P53 Signaling Pathway Diagram
 P53 Signaling Pathway antibodies  P53 Signaling Pathway Diagram
Diseases associated with IGFBP3 elisa kitOrgans/Tissues associated with IGFBP3 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >1197 publications with IGFBP3 and Neoplasms
 Breast Neoplasms Antibodies  >324 publications with IGFBP3 and Breast Neoplasms
 Prostatic Neoplasms Antibodies  >247 publications with IGFBP3 and Prostatic Neoplasms
 Cardiovascular Diseases Antibodies  >205 publications with IGFBP3 and Cardiovascular Diseases
 Adenocarcinoma Antibodies  >164 publications with IGFBP3 and Adenocarcinoma
 Colorectal Neoplasms Antibodies  >138 publications with IGFBP3 and Colorectal Neoplasms
 Liver Diseases Antibodies  >136 publications with IGFBP3 and Liver Diseases
 Kidney Diseases Antibodies  >119 publications with IGFBP3 and Kidney Diseases
 Inflammation Antibodies  >109 publications with IGFBP3 and Inflammation
 Lung Neoplasms Antibodies  >102 publications with IGFBP3 and Lung Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2694 publications with IGFBP3 and Blood
 Bone Antibodies  >488 publications with IGFBP3 and Bone
 Liver Antibodies  >392 publications with IGFBP3 and Liver
 Prostate Antibodies  >336 publications with IGFBP3 and Prostate
 Muscle Antibodies  >276 publications with IGFBP3 and Muscle
 Connective Tissue Antibodies  >207 publications with IGFBP3 and Connective Tissue
 Vascular Antibodies  >205 publications with IGFBP3 and Vascular
 Kidney Antibodies  >198 publications with IGFBP3 and Kidney
 Brain Antibodies  >184 publications with IGFBP3 and Brain
 Lung Antibodies  >166 publications with IGFBP3 and Lung
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