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IL28B elisa kit :: Fish Interleukin 28B ELISA Kit

Scan QR to view Datasheet Catalog #    MBS071467 IL28B elisa kit
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 Product Name   

Interleukin 28B (IL28B), ELISA Kit

 Also Known As   

Fish Interleukin 28B ELISA Kit

 Product Gene Name   

IL28B elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    607402
 3D Structure    ModBase 3D Structure for Q8IZI9
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 Species Reactivity    Fish
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IL28B elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IL28B purchase    MBS071467 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Interleukin 28B (IL28B) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IL28B. The ELISA analytical biochemical technique of the MBS071467 kit is based on IL28B antibody-IL28B antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IL28B antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IL28B. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for IL28B. It may not necessarily be applicable to this product.
 NCBI GI #    28144901
 NCBI GeneID    282617
 NCBI Accession #    NP_742151.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_172139.2 [Other Products]
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 UniProt Primary Accession #    Q8IZI9 [Other Products]
 UniProt Secondary Accession #    Q6VN56; Q7Z4J3; Q8IWL6; A2BDE1 [Other Products]
 UniProt Related Accession #    Q8IZI9 [Other Products]
 Molecular Weight    21,706 Da
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 NCBI Official Full Name    interferon lambda-3
 NCBI Official Synonym Full Names    interferon, lambda 3
 NCBI Official Symbol    IFNL3 [Similar Products]
 NCBI Official Synonym Symbols   
IL28B; IL28C; IL-28B
[Similar Products]
 NCBI Protein Information    interferon lambda-3; IL-28C; IFN-lambda-3; IFN-lambda-4; interleukin 28C; interleukin-28B; interleukin-28C; cytokine Zcyto22; interferon lambda-4; interferon, lambda 4; interleukin 28B (interferon, lambda 3)
 UniProt Protein Name    Interferon lambda-3
 UniProt Synonym Protein Names   
Cytokine Zcyto22; Interleukin-28B; IL-28B; Interleukin-28C
 UniProt Gene Name    IFNL3 [Similar Products]
 UniProt Synonym Gene Names    IL28B; IL28C; ZCYTO22; IFN-lambda-3; IL-28B; IL-28C [Similar Products]
 UniProt Entry Name    IFNL3_HUMAN
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 NCBI Summary for IL28B    This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]
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 UniProt Comments for IL28B    IL-28B: Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Belongs to the IL-28/IL-29 family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19q13.13

Cellular Component: extracellular space

Molecular Function: cytokine activity

Biological Process: positive regulation of immune response; negative regulation of viral genome replication; JAK-STAT cascade; defense response to virus

Disease: Hepatitis C Virus, Susceptibility To
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 Research Articles on IL28B    1. could not find any difference in the predictive impact of any of three SNPs of IFNL4 or IL-28B with regard to susceptibility to HCV or treatment response
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IL28B elisa kitPathways associated with IL28B elisa kit
 Reference Product  PubMed Publications
 IFNA2 elisa kit  >5 publications with IL28B and IFNA2
 ITPA elisa kit  >1 publications with IL28B and ITPA
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Type III Interferon Signaling Pathway antibodies  Type III Interferon Signaling Pathway Diagram
Diseases associated with IL28B elisa kit
 Disease Name  Pubmed Publications
 Hepatitis C Antibodies  >26 publications with IL28B and Hepatitis C
 Hepatitis, Chronic Antibodies  >20 publications with IL28B and Hepatitis, Chronic
 Hepatitis C, Chronic Antibodies  >11 publications with IL28B and Hepatitis C, Chronic
 Hepatitis B, Chronic Antibodies  >3 publications with IL28B and Hepatitis B, Chronic
 Liver Cirrhosis Antibodies  >2 publications with IL28B and Liver Cirrhosis
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