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PDPN elisa kit :: Fish Podoplanin ELISA Kit

Scan QR to view Datasheet Catalog #    MBS008572 PDPN elisa kit
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Podoplanin (PDPN), ELISA Kit

 Also Known As   

Fish Podoplanin ELISA Kit

 Product Gene Name   

PDPN elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 1; NC_000001.10 (13910252..13944452). Location: 1p36.21
 OMIM    608863
 3D Structure    ModBase 3D Structure for Q86YL7
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 Species Reactivity    Fish
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PDPN elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PDPN purchase    MBS008572 is a ready-to-use microwell, strip-or-full plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Podoplanin (PDPN) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PDPN. The ELISA analytical biochemical technique of the MBS008572 kit is based on PDPN antibody-PDPN antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PDPN antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PDPN. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for PDPN. It may not necessarily be applicable to this product.
 NCBI GI #    54792062
 NCBI GeneID    10630
 NCBI Accession #    NP_001006626.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001006625.1 [Other Products]
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 UniProt Primary Accession #    Q86YL7 [Other Products]
 UniProt Secondary Accession #    O60836; O95128; Q7L375; Q8NBQ8; Q8NBR3; A9Z1Y2; B2R6J8; E9PB68; F6QWX5 [Other Products]
 UniProt Related Accession #    Q86YL7 [Other Products]
 Molecular Weight    16,698 Da
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 NCBI Official Full Name    podoplanin isoform d
 NCBI Official Synonym Full Names    podoplanin
 NCBI Official Symbol    PDPN [Similar Products]
 NCBI Official Synonym Symbols   
T1A; GP36; GP40; Gp38; OTS8; T1A-2; AGGRUS; HT1A-1; PA2.26
[Similar Products]
 NCBI Protein Information    podoplanin; T1-alpha; hT1alpha-1; hT1alpha-2; PA2.26 antigen; glycoprotein 36; glycoprotein, 36-KD; lung type I cell membrane associated glycoprotein; lung type-I cell membrane-associated glycoprotein (T1A-2)
 UniProt Protein Name    Podoplanin
 UniProt Synonym Protein Names   
Aggrus; Glycoprotein 36; Gp36; PA2.26 antigen; T1-alpha
 Protein Family    Podoplanin
 UniProt Gene Name    PDPN [Similar Products]
 UniProt Synonym Gene Names    GP36; Gp36; T1A [Similar Products]
 UniProt Entry Name    PDPN_HUMAN
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 NCBI Summary for PDPN    This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
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 UniProt Comments for PDPN    PDPN: May be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. Required for normal lung cell proliferation and alveolus formation at birth. Induces platelet aggregation. Does not have any effect on folic acid or amino acid transport. Does not function as a water channel or as a regulator of aquaporin-type water channels. Belongs to the podoplanin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p36.21

Cellular Component: ruffle; filopodium membrane; microvillus membrane; lamellipodium; integral to plasma membrane; apical plasma membrane; plasma membrane; external side of plasma membrane; filopodium

Molecular Function: folic acid transporter activity; water transporter activity; water channel activity; amino acid transmembrane transporter activity

Biological Process: nervous system development; water transport; cell morphogenesis; positive regulation of cell motility; signal transduction; prostaglandin metabolic process; folic acid transport; cell proliferation; regulation of cell shape; cell-cell adhesion; response to hyperoxia; amino acid transport; lymphangiogenesis; tube morphogenesis; inflammatory response; alveolus development; lung development; positive regulation of cell migration
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 Research Articles on PDPN    1. HSPA9 secreted by oral squamous cell carcinoma cells interacts with podoplanin (PDPN) on their cell surface in an autocrine manner and regulates their growth and invasiveness.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PDPN elisa kitDiseases associated with PDPN elisa kit
 Reference Product  PubMed Publications
 LYVE1 elisa kit  >39 publications with PDPN and LYVE1
 VEGFC elisa kit  >27 publications with PDPN and VEGFC
 CD9 elisa kit  >2 publications with PDPN and CD9
 FLT4 elisa kit  >1 publications with PDPN and FLT4
 LGALS8 elisa kit  >1 publications with PDPN and LGALS8
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >248 publications with PDPN and Neoplasms
 Carcinoma Antibodies  >126 publications with PDPN and Carcinoma
 Adenocarcinoma Antibodies  >47 publications with PDPN and Adenocarcinoma
 Lung Neoplasms Antibodies  >28 publications with PDPN and Lung Neoplasms
 Breast Neoplasms Antibodies  >25 publications with PDPN and Breast Neoplasms
 Lung Diseases Antibodies  >25 publications with PDPN and Lung Diseases
 Inflammation Antibodies  >20 publications with PDPN and Inflammation
 Cardiovascular Diseases Antibodies  >16 publications with PDPN and Cardiovascular Diseases
 Adenoma Antibodies  >15 publications with PDPN and Adenoma
 Precancerous Conditions Antibodies  >10 publications with PDPN and Precancerous Conditions
Organs/Tissues associated with PDPN elisa kit
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >140 publications with PDPN and Vascular
 Lymph Node Antibodies  >98 publications with PDPN and Lymph Node
 Blood Antibodies  >98 publications with PDPN and Blood
 Skin Antibodies  >53 publications with PDPN and Skin
 Lung Antibodies  >38 publications with PDPN and Lung
 Mouth Antibodies  >33 publications with PDPN and Mouth
 Muscle Antibodies  >23 publications with PDPN and Muscle
 Brain Antibodies  >22 publications with PDPN and Brain
 Kidney Antibodies  >21 publications with PDPN and Kidney
 Eye Antibodies  >17 publications with PDPN and Eye
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