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SREBP elisa kit :: Fish Sterol Regulatory Element Binding Proteins ELISA Kit

Scan QR to view Datasheet Catalog #    MBS018231 SREBP elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Sterol Regulatory Element Binding Proteins (SREBP), ELISA Kit

 Also Known As   

Fish Sterol Regulatory Element Binding Proteins ELISA Kit

 Product Gene Name   

SREBP elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    600481
 3D Structure    ModBase 3D Structure for Q12772
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 Species Reactivity    Fish
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SREBP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SREBP purchase    MBS018231 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Sterol Regulatory Element Binding Proteins (SREBP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SREBP. The ELISA analytical biochemical technique of the MBS018231 kit is based on SREBP antibody-SREBP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SREBP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SREBP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for SREBP. It may not necessarily be applicable to this product.
 NCBI GI #    451330
 NCBI GeneID    6721
 NCBI Accession #    AAA50746.1 [Other Products]
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 UniProt Primary Accession #    Q12772 [Other Products]
 UniProt Secondary Accession #    Q05BD5; Q6GTH7; Q86V36; Q9UH04 [Other Products]
 UniProt Related Accession #    Q12772 [Other Products]
 Molecular Weight    123,688 Da
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 NCBI Official Full Name    sterol regulatory element binding protein-2
 NCBI Official Synonym Full Names    sterol regulatory element binding transcription factor 2
 NCBI Official Symbol    SREBF2 [Similar Products]
 NCBI Official Synonym Symbols   
SREBP2; bHLHd2; SREBP-2
[Similar Products]
 NCBI Protein Information    sterol regulatory element-binding protein 2; class D basic helix-loop-helix protein 2; sterol regulatory element-binding transcription factor 2
 UniProt Protein Name    Sterol regulatory element-binding protein 2
 UniProt Synonym Protein Names   
Class D basic helix-loop-helix protein 2; bHLHd2; Sterol regulatory element-binding transcription factor 2
 UniProt Gene Name    SREBF2 [Similar Products]
 UniProt Synonym Gene Names    BHLHD2; SREBP2; SREBP-2; bHLHd2 [Similar Products]
 UniProt Entry Name    SRBP2_HUMAN
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 NCBI Summary for SREBP    This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
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 UniProt Comments for SREBP    SREBP-2: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway. Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes. Belongs to the SREBP family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 22q13

Cellular Component: nucleoplasm; Golgi membrane; endoplasmic reticulum membrane; endoplasmic reticulum; cytoplasm; nucleolus; cytosol; nucleus

Molecular Function: protein dimerization activity; protein C-terminus binding; protein binding; C-8 sterol isomerase activity

Biological Process: cholesterol metabolic process; transcription, DNA-dependent; response to low density lipoprotein stimulus; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; lipid metabolic process; cellular lipid metabolic process
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 Research Articles on SREBP    1. Rating SREBF2 polymorphism did not reveal a relationship to the occurrence of ischemic heart disease in patients with obstructive sleep apnea, both in the whole group as well as separate subgroups.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SREBP elisa kitPathways associated with SREBP elisa kit
 Reference Product  PubMed Publications
 SCAP elisa kit  >44 publications with SREBP and SCAP
 INSIG1 elisa kit  >15 publications with SREBP and INSIG1
 SP1 elisa kit  >12 publications with SREBP and SP1
 INSIG2 elisa kit  >11 publications with SREBP and INSIG2
 FDPS elisa kit  >2 publications with SREBP and FDPS
 CREBBP elisa kit  >2 publications with SREBP and CREBBP
 Products by Pathway  Pathway Diagram
 Activation Of Gene Expression By SREBF (SREBP) Pathway antibodies  Activation Of Gene Expression By SREBF (SREBP) Pathway Diagram
 Cholesterol Biosynthesis Pathway antibodies  Cholesterol Biosynthesis Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 PPARA Activates Gene Expression Pathway antibodies  PPARA Activates Gene Expression Pathway Diagram
 Regulation Of Cholesterol Biosynthesis By SREBP (SREBF) Pathway antibodies  Regulation Of Cholesterol Biosynthesis By SREBP (SREBF) Pathway Diagram
 Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway antibodies  Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway Diagram
 SREBF And MiR33 In Cholesterol And Lipid Homeostasis Pathway antibodies  SREBF And MiR33 In Cholesterol And Lipid Homeostasis Pathway Diagram
Diseases associated with SREBP elisa kitOrgans/Tissues associated with SREBP elisa kit
 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >84 publications with SREBP and Fatty Liver
 Dyslipidemias Antibodies  >47 publications with SREBP and Dyslipidemias
 Atherosclerosis Antibodies  >43 publications with SREBP and Atherosclerosis
 Cardiovascular Diseases Antibodies  >38 publications with SREBP and Cardiovascular Diseases
 Hyperlipidemias Antibodies  >37 publications with SREBP and Hyperlipidemias
 Neoplasms Antibodies  >36 publications with SREBP and Neoplasms
 Hypercholesterolemia Antibodies  >32 publications with SREBP and Hypercholesterolemia
 Disease Models, Animal Antibodies  >29 publications with SREBP and Disease Models, Animal
 Insulin Resistance Antibodies  >26 publications with SREBP and Insulin Resistance
 Inflammation Antibodies  >23 publications with SREBP and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >179 publications with SREBP and Liver
 Blood Antibodies  >85 publications with SREBP and Blood
 Adipose Tissue Antibodies  >28 publications with SREBP and Adipose Tissue
 Brain Antibodies  >23 publications with SREBP and Brain
 Kidney Antibodies  >21 publications with SREBP and Kidney
 Muscle Antibodies  >19 publications with SREBP and Muscle
 Heart Antibodies  >19 publications with SREBP and Heart
 Intestine Antibodies  >18 publications with SREBP and Intestine
 Prostate Antibodies  >17 publications with SREBP and Prostate
 Connective Tissue Antibodies  >15 publications with SREBP and Connective Tissue
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