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TLR9 elisa kit :: Fish Toll Like Receptor 9 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS009835 TLR9 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Toll Like Receptor 9 (TLR9), ELISA Kit

 Also Known As   

Fish Toll Like Receptor 9 ELISA Kit

 Product Gene Name   

TLR9 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 3; NC_000003.11 (52255096..52260179, complement). Location: 3p21.3
 OMIM    605474
 3D Structure    ModBase 3D Structure for Q9NR96
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 Species Reactivity    Fish
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TLR9 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TLR9 purchase    MBS009835 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Toll Like Receptor 9 (TLR9) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TLR9. The ELISA analytical biochemical technique of the MBS009835 kit is based on TLR9 antibody-TLR9 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TLR9 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TLR9. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for TLR9. It may not necessarily be applicable to this product.
 NCBI GI #    74054321
 NCBI GeneID    54106
 NCBI Accession #    AAZ95520.1 [Other Products]
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 UniProt Primary Accession #    Q9NR96 [Other Products]
 UniProt Secondary Accession #    Q6UVZ2; Q9HD68; Q9HD69; Q9HD70; Q9NYC2; Q9NYC3; B3Y661; D1CS56 [Other Products]
 UniProt Related Accession #    Q9NR96 [Other Products]
 Molecular Weight    115,860 Da
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 NCBI Official Full Name    TLR9
 NCBI Official Synonym Full Names    toll-like receptor 9
 NCBI Official Symbol    TLR9 [Similar Products]
 NCBI Official Synonym Symbols   
CD289
[Similar Products]
 NCBI Protein Information    toll-like receptor 9
 UniProt Protein Name    Toll-like receptor 9
 Protein Family    Toll-like receptor
 UniProt Gene Name    TLR9 [Similar Products]
 UniProt Entry Name    TLR9_HUMAN
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 NCBI Summary for TLR9    The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Jul 2008]
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 UniProt Comments for TLR9    TLR9: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Controls lymphocyte response to Helicobacter infection. Interacts with MYD88 via their respective TIR domains. Interacts (via transmembrane domain) with UNC93B1. Interacts with CD300LH; the interaction may promote full activation of TLR9-triggered innate responses. Interacts with BTK. Interacts with CNPY3 and HSP90B1; this interaction is required for proper folding in the endoplasmic reticulum. Highly expressed in spleen, lymph node, tonsil and peripheral blood leukocytes, especially in plasmacytoid pre- dendritic cells. Levels are much lower in monocytes and CD11c+ immature dendritic cells. Also detected in lung and liver. Belongs to the Toll-like receptor family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: Golgi membrane; endoplasmic reticulum membrane; endoplasmic reticulum; basolateral plasma membrane; lysosome; apical plasma membrane; cytoplasm; extracellular region; integral to membrane; plasma membrane; endosome membrane; endosome

Molecular Function: transmembrane receptor activity; siRNA binding; interleukin-1 receptor binding

Biological Process: positive regulation of JNK activity; regulation of cytokine secretion; positive regulation of interleukin-12 production; maintenance of gastrointestinal epithelium; positive regulation of JNK cascade; positive regulation of NF-kappaB import into nucleus; positive regulation of interferon-alpha biosynthetic process; positive regulation of interleukin-18 production; defense response to Gram-negative bacterium; positive regulation of interleukin-10 production; activation of NF-kappaB transcription factor; positive regulation of interleukin-8 production; response to molecule of bacterial origin; negative regulation of interleukin-8 production; negative regulation of interleukin-6 production; positive regulation of interferon-beta production; inflammatory response; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of interleukin-6 production; positive regulation of tumor necrosis factor production; positive regulation of chemokine production; positive regulation of toll-like receptor signaling pathway; MyD88-dependent toll-like receptor signaling pathway; inhibition of NF-kappaB transcription factor; positive regulation of interferon-beta biosynthetic process; defense response to bacterium; insulin receptor signaling pathway; toll-like receptor signaling pathway; negative regulation of toll-like receptor signaling pathway; innate immune response; positive regulation of transcription from RNA polymerase II promoter; toll-like receptor 9 signaling pathway; I-kappaB phosphorylation; positive regulation of nitric-oxide synthase biosynthetic process; positive regulation of interferon-gamma biosynthetic process; positive regulation of inflammatory response
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 Research Articles on TLR9    1. role of TLR-9 in antiviral innate immune sensing of MVMp and H-1PV
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TLR9 elisa kitPathways associated with TLR9 elisa kit
 Reference Product  PubMed Publications
 TLR7 elisa kit  >616 publications with TLR9 and TLR7
 TLR3 elisa kit  >491 publications with TLR9 and TLR3
 MYD88 elisa kit  >408 publications with TLR9 and MYD88
 CD40 elisa kit  >145 publications with TLR9 and CD40
 CD86 elisa kit  >109 publications with TLR9 and CD86
 CTSB elisa kit  >2 publications with TLR9 and CTSB
 HSP90B1 elisa kit  >2 publications with TLR9 and HSP90B1
 CTSK elisa kit  >1 publications with TLR9 and CTSK
 CNPY3 elisa kit  >1 publications with TLR9 and CNPY3
 Products by Pathway  Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 IGF1R Signaling Cascade Pathway antibodies  IGF1R Signaling Cascade Pathway Diagram
 IRS-mediated Signalling Pathway antibodies  IRS-mediated Signalling Pathway Diagram
 IRS-related Events Pathway antibodies  IRS-related Events Pathway Diagram
 IRS-related Events Triggered By IGF1R Pathway antibodies  IRS-related Events Triggered By IGF1R Pathway Diagram
Diseases associated with TLR9 elisa kitOrgans/Tissues associated with TLR9 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >506 publications with TLR9 and Inflammation
 Necrosis Antibodies  >367 publications with TLR9 and Necrosis
 Disease Models, Animal Antibodies  >207 publications with TLR9 and Disease Models, Animal
 Nervous System Diseases Antibodies  >97 publications with TLR9 and Nervous System Diseases
 Hepatitis Antibodies  >78 publications with TLR9 and Hepatitis
 Cardiovascular Diseases Antibodies  >70 publications with TLR9 and Cardiovascular Diseases
 Kidney Diseases Antibodies  >61 publications with TLR9 and Kidney Diseases
 Brain Diseases Antibodies  >50 publications with TLR9 and Brain Diseases
 Drug Toxicity Antibodies  >38 publications with TLR9 and Drug Toxicity
 Lung Neoplasms Antibodies  >34 publications with TLR9 and Lung Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1299 publications with TLR9 and Blood
 Lymph Node Antibodies  >103 publications with TLR9 and Lymph Node
 Lymph Antibodies  >94 publications with TLR9 and Lymph
 Thymus Antibodies  >16 publications with TLR9 and Thymus
 Tonsil Antibodies  >16 publications with TLR9 and Tonsil
 Trachea Antibodies  >5 publications with TLR9 and Trachea
 Thyroid Antibodies  >3 publications with TLR9 and Thyroid
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