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LTB4 elisa kit :: General LTB4 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2515771 (SPECIAL PROMOTIONAL PRICING for a limited time)
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $310 +1 FREE 8GB USB
96-Strip-Wells  /  $355 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,435 +1 FREE 8GB USB
10x96-Strip-Wells  /  $2,805 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

LTB4, ELISA Kit

★Popular Item★
 Also Known As   

LTB4 (Leukotriene B4) ELISA Kit

 Product Gene Name   

LTB4 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2515771 COA    COA PDF
 OMIM    605773
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 Species Reactivity    General
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 Specificity    This kit recognizes natural and some recombinant LTB4. No significant cross-reactivity or interference between LTB4 and analogues was observed.
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 Samples    Serum, plasma and other biological fluids
 Assay Type    Quantitative Competitive
 Detection Range    15.63-1000 pg/mL
 Sensitivity    9.38 pg/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of LTB4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for LTB4 purchase    MBS2515771 is a ready-to-use microwell, strip plate Quantitative Competitive ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the LTB4, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 15.63-1000 pg/mL in biological research samples containing LTB4, with an estimated sensitivity of 9.38 pg/mL. The ELISA analytical biochemical technique of the MBS2515771 kit is based on LTB4 antibody-LTB4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LTB4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LTB4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for LTB4 elisa kit

   Intended Uses: This ELISA kit can be applied to the in vitro quantitative determination of LTB4 concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Competitive-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to LTB4. During the reaction, LTB4 in the sample or standard competes with a fixed amount of LTB4 on the solid phase supporter for sites on the Biotinylated Detection Ab specific to LTB4. Excess conjugate and unbound sample or standard are washed from the plate, and Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then the Substrate Reagent is added to each well. The enzyme-substrate reaction is terminated by adding Stop Solution and the color change can be measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of LTB4 in samples can be calculated by comparing the OD of the samples with the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of LTB4 elisa kit    LTB4 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2515771. Click to request current manual
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NCBI/Uniprot data below describe general gene information for LTB4. It may not necessarily be applicable to this product.
 NCBI GI #    9081803
 NCBI GeneID    56413
 NCBI Accession #    BAA99539.1 [Other Products]
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 UniProt Secondary Accession #    Q5KU28; Q9NPE5 [Other Products]
 UniProt Related Accession #    Q9NPC1 [Other Products]
 Molecular Weight    37,942 Da
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 NCBI Official Full Name    LTB4 receptor JULF2
 NCBI Official Synonym Full Names    leukotriene B4 receptor 2
 NCBI Official Symbol    LTB4R2 [Similar Products]
 NCBI Official Synonym Symbols   
BLT2; NOP9; BLTR2; JULF2; KPG_004; LTB4-R2; LTB4-R 2
[Similar Products]
 NCBI Protein Information    leukotriene B4 receptor 2; LTB4 receptor JULF2; leukotriene B4 receptor BLT2; seven transmembrane receptor BLTR2
 UniProt Protein Name    Leukotriene B4 receptor 2
 UniProt Synonym Protein Names   
LTB4 receptor JULF2; Leukotriene B4 receptor BLT2; Seven transmembrane receptor BLTR2
 UniProt Gene Name    LTB4R2 [Similar Products]
 UniProt Synonym Gene Names    BLT2R; BLTR2; LTB4-R 2; LTB4-R2 [Similar Products]
 UniProt Entry Name    LT4R2_HUMAN
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 UniProt Comments for LTB4    LTB4R2: Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3. Belongs to the G-protein coupled receptor 1 family.

Protein type: Motility/polarity/chemotaxis; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 14q12

Cellular Component: membrane; integral to plasma membrane; plasma membrane

Molecular Function: leukotriene B4 receptor activity; leukotriene receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; negative regulation of adenylate cyclase activity; chemotaxis; keratinocyte migration
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 Research Articles on LTB4    1. BLT2-NOX-ROS-NF-kappaB cascade induction during detachment confers a novel mechanism of anoikis resistance in prostate cancer cells and potentially contributes to prostate cancer progression.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with LTB4 elisa kitPathways associated with LTB4 elisa kit
 Reference Product  PubMed Publications
 LTB4R elisa kit  >24 publications with LTB4 and LTB4R
 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Eicosanoid Ligand-binding Receptors Pathway antibodies  Eicosanoid Ligand-binding Receptors Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Other Pathway antibodies  GPCRs, Other Pathway Diagram
Diseases associated with LTB4 elisa kitOrgans/Tissues associated with LTB4 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >19 publications with LTB4 and Inflammation
 Disease Models, Animal Antibodies  >4 publications with LTB4 and Disease Models, Animal
 Necrosis Antibodies  >4 publications with LTB4 and Necrosis
 Neoplasm Metastasis Antibodies  >3 publications with LTB4 and Neoplasm Metastasis
 Nervous System Diseases Antibodies  >2 publications with LTB4 and Nervous System Diseases
 Brain Diseases Antibodies  >2 publications with LTB4 and Brain Diseases
 Diabetes Mellitus Antibodies  >1 publications with LTB4 and Diabetes Mellitus
 Kidney Diseases Antibodies  >1 publications with LTB4 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >22 publications with LTB4 and Blood
 Lung Antibodies  >8 publications with LTB4 and Lung
 Bone Antibodies  >5 publications with LTB4 and Bone
 Intestine Antibodies  >3 publications with LTB4 and Intestine
 Ovary Antibodies  >3 publications with LTB4 and Ovary
 Prostate Antibodies  >2 publications with LTB4 and Prostate
 Embryonic Tissue Antibodies  >2 publications with LTB4 and Embryonic Tissue
 Kidney Antibodies  >1 publications with LTB4 and Kidney
 Pancreas Antibodies  >1 publications with LTB4 and Pancreas
 Spleen Antibodies  >1 publications with LTB4 and Spleen
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