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YWHAB elisa kit :: Goat 14-3-3 protein beta/alpha (YWHAB) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7224365 YWHAB elisa kit
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

14-3-3 protein beta/alpha (YWHAB), ELISA Kit

 Also Known As   

Goat 14-3-3 protein beta/alpha (YWHAB) ELISA Kit

 Product Gene Name   

YWHAB elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    601289
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 Species Reactivity    Goat
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
 Assay Type    Competitive
 Detection Range    50-1000ng/mL
 Sensitivity    1.0ng/mL
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of YWHAB elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for YWHAB purchase    MBS7224365 is a ready-to-use microwell, strip plate Competitive ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 14-3-3 protein beta/alpha (YWHAB) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 50-1000ng/mL in biological research samples containing YWHAB, with an estimated sensitivity of 1.0ng/mL. The ELISA analytical biochemical technique of the MBS7224365 kit is based on YWHAB antibody-YWHAB antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect YWHAB antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, YWHAB. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for YWHAB elisa kit    Signal Transduction
NCBI/Uniprot data below describe general gene information for YWHAB. It may not necessarily be applicable to this product.
 NCBI GI #    21328448
 NCBI GeneID    7529
 NCBI Accession #    NP_647539.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_139323.3 [Other Products]
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 UniProt Secondary Accession #    A8K9K2; E1P616 [Other Products]
 UniProt Related Accession #    P31946 [Other Products]
 Molecular Weight    27,850 Da [Similar Products]
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 NCBI Official Full Name    14-3-3 protein beta/alpha
 NCBI Official Synonym Full Names    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
 NCBI Official Symbol    YWHAB [Similar Products]
 NCBI Official Synonym Symbols   
HS1; GW128; YWHAA; KCIP-1; HEL-S-1
[Similar Products]
 NCBI Protein Information    14-3-3 protein beta/alpha; 14-3-3 alpha; protein 1054; epididymis secretory protein Li 1; brain protein 14-3-3, beta isoform; protein kinase C inhibitor protein 1; protein kinase C inhibitor protein-1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, alpha polypeptide
 UniProt Protein Name    14-3-3 protein beta/alpha
 UniProt Synonym Protein Names   
Protein 1054; Protein kinase C inhibitor protein 1; KCIP-1
 Protein Family    14-3-3 protein
 UniProt Gene Name    YWHAB [Similar Products]
 UniProt Synonym Gene Names    KCIP-1 [Similar Products]
 UniProt Entry Name    1433B_HUMAN
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 NCBI Summary for YWHAB    This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for YWHAB    14-3-3 beta: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 20q13.1

Cellular Component: cytoplasmic vesicle membrane; focal adhesion; transcriptional repressor complex; membrane; perinuclear region of cytoplasm; cytoplasm; melanosome; nucleus; cytosol

Molecular Function: protein C-terminus binding; protein domain specific binding; protein binding; enzyme binding; histone deacetylase binding; protein complex binding; phosphoprotein binding; transcription corepressor activity; phosphoserine binding

Biological Process: epidermal growth factor receptor signaling pathway; positive regulation of catalytic activity; negative regulation of protein amino acid dephosphorylation; axon guidance; fibroblast growth factor receptor signaling pathway; activation of MAPKK activity; nerve growth factor receptor signaling pathway; protein heterooligomerization; apoptosis; MAPKKK cascade; small GTPase mediated signal transduction; Ras protein signal transduction; insulin receptor signaling pathway; cytoplasmic sequestering of protein; innate immune response; gene expression; negative regulation of transcription, DNA-dependent; vascular endothelial growth factor receptor signaling pathway; protein targeting
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 Research Articles on YWHAB    1. Using gene reporter assays, we show that promoter variations in 11 intrinsic apoptosis genes, including ADPRT, APAF1, BCL2, BAD, BID, MCL1, BIRC4, BCL2L1, ENDOG, YWHAB, and YWHAQ, influence promoter activity in an allele-specific manner.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with YWHAB elisa kitPathways associated with YWHAB elisa kit
 Reference Product  PubMed Publications
 CDC25B elisa kit  >3 publications with YWHAB and CDC25B
 BAD elisa kit  >2 publications with YWHAB and BAD
 CDC25C elisa kit  >2 publications with YWHAB and CDC25C
 HDAC4 elisa kit  >1 publications with YWHAB and HDAC4
 TSC2 elisa kit  >1 publications with YWHAB and TSC2
 Products by Pathway  Pathway Diagram
 ARMS-mediated Activation Pathway antibodies  ARMS-mediated Activation Pathway Diagram
 Activation Of BAD And Translocation To Mitochondria Pathway antibodies  Activation Of BAD And Translocation To Mitochondria Pathway Diagram
 Activation Of BH3-only Proteins Pathway antibodies  Activation Of BH3-only Proteins Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Butyrate Response Factor 1 (BRF1) Destabilizes MRNA Pathway antibodies  Butyrate Response Factor 1 (BRF1) Destabilizes MRNA Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
Diseases associated with YWHAB elisa kitOrgans/Tissues associated with YWHAB elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >13 publications with YWHAB and Nervous System Diseases
 Carcinoma Antibodies  >6 publications with YWHAB and Carcinoma
 Liver Diseases Antibodies  >4 publications with YWHAB and Liver Diseases
 Inflammation Antibodies  >3 publications with YWHAB and Inflammation
 Neoplasm Metastasis Antibodies  >2 publications with YWHAB and Neoplasm Metastasis
 Cardiovascular Diseases Antibodies  >2 publications with YWHAB and Cardiovascular Diseases
 Liver Neoplasms Antibodies  >2 publications with YWHAB and Liver Neoplasms
 Seizures Antibodies  >2 publications with YWHAB and Seizures
 Carcinoma, Hepatocellular Antibodies  >2 publications with YWHAB and Carcinoma, Hepatocellular
 Necrosis Antibodies  >2 publications with YWHAB and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >12 publications with YWHAB and Brain
 Blood Antibodies  >5 publications with YWHAB and Blood
 Liver Antibodies  >4 publications with YWHAB and Liver
 Muscle Antibodies  >4 publications with YWHAB and Muscle
 Kidney Antibodies  >3 publications with YWHAB and Kidney
 Nerve Antibodies  >3 publications with YWHAB and Nerve
 Lung Antibodies  >2 publications with YWHAB and Lung
 Ganglia Antibodies  >2 publications with YWHAB and Ganglia
 Vascular Antibodies  >2 publications with YWHAB and Vascular
 Heart Antibodies  >2 publications with YWHAB and Heart
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