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OGDH elisa kit :: Goat 2-oxoglutae dehydrogenase, mitochondrial (OGDH) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7209242 OGDH elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

2-oxoglutae dehydrogenase, mitochondrial (OGDH), ELISA Kit

 Also Known As   

Goat 2-oxoglutae dehydrogenase, mitochondrial (OGDH) ELISA Kit

 Product Gene Name   

OGDH elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 OMIM    613022
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 Species Reactivity    Goat
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of OGDH elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for OGDH purchase    MBS7209242 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 2-oxoglutae dehydrogenase, mitochondrial (OGDH) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing OGDH. The ELISA analytical biochemical technique of the MBS7209242 kit is based on OGDH antibody-OGDH antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect OGDH antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, OGDH. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for OGDH elisa kit    Cardiovascular
NCBI/Uniprot data below describe general gene information for OGDH. It may not necessarily be applicable to this product.
 NCBI GI #    51873038
 NCBI GeneID    4967
 NCBI Accession #    NP_001003941.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001003941.2 [Other Products]
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 UniProt Secondary Accession #    Q96DD3; Q9UDX0; B4E2U9; D3DVL0; E9PBM1 [Other Products]
 UniProt Related Accession #    Q02218 [Other Products]
 Molecular Weight    48,180 Da
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 NCBI Official Full Name    2-oxoglutarate dehydrogenase, mitochondrial isoform 2
 NCBI Official Synonym Full Names    oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
 NCBI Official Symbol    OGDH [Similar Products]
 NCBI Official Synonym Symbols   
E1k; OGDC; AKGDH
[Similar Products]
 NCBI Protein Information    2-oxoglutarate dehydrogenase, mitochondrial; OGDC-E1; oxoglutarate decarboxylase; 2-oxoglutarate dehydrogenase complex component E1; oxoglutarate dehydrogenase (succinyl-transferring)
 UniProt Protein Name    2-oxoglutarate dehydrogenase, mitochondrial
 UniProt Synonym Protein Names   
2-oxoglutarate dehydrogenase complex component E1; OGDC-E1; Alpha-ketoglutarate dehydrogenase
 UniProt Gene Name    OGDH [Similar Products]
 UniProt Synonym Gene Names    OGDC-E1 [Similar Products]
 UniProt Entry Name    ODO1_HUMAN
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 NCBI Summary for OGDH    This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009]
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 UniProt Comments for OGDH    OGDH: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the alpha-ketoglutarate dehydrogenase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Carbohydrate Metabolism - citrate (TCA) cycle; Oxidoreductase; EC 1.2.4.2; Amino Acid Metabolism - tryptophan; Amino Acid Metabolism - lysine degradation

Chromosomal Location of Human Ortholog: 7p14-p13

Cellular Component: mitochondrion; mitochondrial matrix; mitochondrial membrane; cytosol; oxoglutarate dehydrogenase complex

Molecular Function: chaperone binding; metal ion binding; heat shock protein binding; thiamin pyrophosphate binding; oxoglutarate dehydrogenase (succinyl-transferring) activity

Biological Process: generation of precursor metabolites and energy; glycolysis; striatum development; tricarboxylic acid cycle; succinyl-CoA metabolic process; hippocampus development; pyramidal neuron development; thalamus development; 2-oxoglutarate metabolic process; cellular metabolic process; cerebellar cortex development; tangential migration from the subventricular zone to the olfactory bulb; NADH metabolic process; lysine catabolic process

Disease: Alpha-ketoglutarate Dehydrogenase Deficiency
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 Research Articles on OGDH    1. ATP consumption is demonstrated in respiration-impaired isolated mice and in situ neuronal mitochondria from transgenic mice with dihydrolipoyl succinyltransferase deficiency.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with OGDH elisa kitPathways associated with OGDH elisa kit
 Reference Product  PubMed Publications
 IDH3G elisa kit  >1 publications with OGDH and IDH3G
 IDH3A elisa kit  >1 publications with OGDH and IDH3A
 DLST elisa kit  >1 publications with OGDH and DLST
 Products by Pathway  Pathway Diagram
 2-oxoglutarate Decarboxylation To Succinyl-CoA Pathway antibodies  2-oxoglutarate Decarboxylation To Succinyl-CoA Pathway Diagram
 2-oxoglutarate Decarboxylation To Succinyl-CoA Pathway antibodies  2-oxoglutarate Decarboxylation To Succinyl-CoA Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Citrate Cycle (TCA Cycle) Pathway antibodies  Citrate Cycle (TCA Cycle) Pathway Diagram
 Citrate Cycle (TCA Cycle) Pathway antibodies  Citrate Cycle (TCA Cycle) Pathway Diagram
 Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway antibodies  Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway Diagram
 Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway antibodies  Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway Diagram
 Citrate Cycle, Second Carbon Oxidation, 2-oxoglutarate => Oxaloacetate Pathway antibodies  Citrate Cycle, Second Carbon Oxidation, 2-oxoglutarate => Oxaloacetate Pathway Diagram
 Citrate Cycle, Second Carbon Oxidation, 2-oxoglutarate => Oxaloacetate Pathway antibodies  Citrate Cycle, Second Carbon Oxidation, 2-oxoglutarate => Oxaloacetate Pathway Diagram
Diseases associated with OGDH elisa kitOrgans/Tissues associated with OGDH elisa kit
 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >3 publications with OGDH and Heart Diseases
 Nervous System Diseases Antibodies  >2 publications with OGDH and Nervous System Diseases
 Liver Diseases Antibodies  >2 publications with OGDH and Liver Diseases
 Atherosclerosis Antibodies  >1 publications with OGDH and Atherosclerosis
 Brain Diseases Antibodies  >1 publications with OGDH and Brain Diseases
 Disease Models, Animal Antibodies  >1 publications with OGDH and Disease Models, Animal
 Liver Cirrhosis Antibodies  >1 publications with OGDH and Liver Cirrhosis
 Fatty Liver Antibodies  >1 publications with OGDH and Fatty Liver
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >15 publications with OGDH and Muscle
 Heart Antibodies  >8 publications with OGDH and Heart
 Liver Antibodies  >8 publications with OGDH and Liver
 Blood Antibodies  >5 publications with OGDH and Blood
 Brain Antibodies  >5 publications with OGDH and Brain
 Kidney Antibodies  >3 publications with OGDH and Kidney
 Pancreas Antibodies  >3 publications with OGDH and Pancreas
 Adipose Tissue Antibodies  >3 publications with OGDH and Adipose Tissue
 Vascular Antibodies  >3 publications with OGDH and Vascular
 Connective Tissue Antibodies  >2 publications with OGDH and Connective Tissue
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