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ACSS2 elisa kit :: Goat Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7221438 ACSS2 elisa kit
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2), ELISA Kit

 Also Known As   

Goat Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2) ELISA Kit

 Product Gene Name   

ACSS2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    605832
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 Species Reactivity    Goat
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ACSS2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ACSS2 purchase    MBS7221438 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ACSS2. The ELISA analytical biochemical technique of the MBS7221438 kit is based on ACSS2 antibody-ACSS2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ACSS2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ACSS2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for ACSS2 elisa kit    Cell Markers
NCBI/Uniprot data below describe general gene information for ACSS2. It may not necessarily be applicable to this product.
 NCBI GI #    253970489
 NCBI GeneID    55902
 NCBI Accession #    NP_001070020.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001076552.2 [Other Products]
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 UniProt Secondary Accession #    Q5QPH2; Q5QPH3; Q8N238; Q96EL0; Q9NQP7; Q9UJ15; A6NE90 [Other Products]
 UniProt Related Accession #    Q9NR19 [Other Products]
 Molecular Weight    80,087 Da
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 NCBI Official Full Name    acetyl-coenzyme A synthetase, cytoplasmic isoform 2
 NCBI Official Synonym Full Names    acyl-CoA synthetase short-chain family member 2
 NCBI Official Symbol    ACSS2 [Similar Products]
 NCBI Official Synonym Symbols   
ACS; ACSA; ACAS2; ACECS; dJ1161H23.1
[Similar Products]
 NCBI Protein Information    acetyl-coenzyme A synthetase, cytoplasmic; acetate thiokinase; acetate-CoA ligase; acyl-activating enzyme; cytoplasmic acetyl-coenzyme A synthetase; acetyl-Coenzyme A synthetase 2 (ADP forming)
 UniProt Protein Name    Acetyl-coenzyme A synthetase, cytoplasmic
 UniProt Synonym Protein Names   
Acetate--CoA ligase; Acetyl-CoA synthetase; ACS; AceCS; Acyl-CoA synthetase short-chain family member 2; Acyl-activating enzyme
 Protein Family    Acetyl-coenzyme A synthetase
 UniProt Gene Name    ACSS2 [Similar Products]
 UniProt Synonym Gene Names    ACAS2; ACS; AceCS [Similar Products]
 UniProt Entry Name    ACSA_HUMAN
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 NCBI Summary for ACSS2    This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]
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 UniProt Comments for ACSS2    ACSS2: Activates acetate so that it can be used for lipid synthesis or for energy generation. Monomer. Belongs to the ATP-dependent AMP-binding enzyme family.

Protein type: Ligase; Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 6.2.1.1; Carbohydrate Metabolism - propanoate; Carbohydrate Metabolism - pyruvate

Chromosomal Location of Human Ortholog: 20q11.22

Cellular Component: nucleoplasm; intracellular membrane-bound organelle; cytoplasm; cytosol

Molecular Function: acetate-CoA ligase activity; ATP binding; AMP binding

Biological Process: acetyl-CoA biosynthetic process from acetate; xenobiotic metabolic process; lipid biosynthetic process; ethanol oxidation; propionate biosynthetic process; acetate biosynthetic process
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 Research Articles on ACSS2    1. During hypoxia, ACSS2 modulates interactions of the acetylase/coactivator CBP with the stress-responsive transcription factor, HIF-2. These interactions include acetylation of HIF-2 by CBP as well as stable HIF-2/CBP complex formation, both of which are required for maximal HIF-2 signaling. Thus, ACSS2 links changes in metabolism that occur during stress with activation of a selective nuclear signaling pathway.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ACSS2 elisa kitPathways associated with ACSS2 elisa kit
 Reference Product  PubMed Publications
 ACACA elisa kit  >5 publications with ACSS2 and ACACA
 ALDH1A1 elisa kit  >1 publications with ACSS2 and ALDH1A1
 ALDH3B1 elisa kit  >1 publications with ACSS2 and ALDH3B1
 ACACB elisa kit  >1 publications with ACSS2 and ACACB
 Products by Pathway  Pathway Diagram
 Amino Acid Conjugation Of Benzoic Acid Pathway antibodies  Amino Acid Conjugation Of Benzoic Acid Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Ethanol Oxidation Pathway antibodies  Ethanol Oxidation Pathway Diagram
 Fatty Acid Beta Oxidation Pathway antibodies  Fatty Acid Beta Oxidation Pathway Diagram
 Fatty Acid Biosynthesis Pathway antibodies  Fatty Acid Biosynthesis Pathway Diagram
 Glycolysis / Gluconeogenesis Pathway antibodies  Glycolysis / Gluconeogenesis Pathway Diagram
 Glycolysis / Gluconeogenesis Pathway antibodies  Glycolysis / Gluconeogenesis Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
Diseases associated with ACSS2 elisa kitOrgans/Tissues associated with ACSS2 elisa kit
 Disease Name  Pubmed Publications
 Insulin Resistance Antibodies  >3 publications with ACSS2 and Insulin Resistance
 Atherosclerosis Antibodies  >2 publications with ACSS2 and Atherosclerosis
 Hyperglycemia Antibodies  >2 publications with ACSS2 and Hyperglycemia
 Fatty Liver Antibodies  >2 publications with ACSS2 and Fatty Liver
 Weight Gain Antibodies  >2 publications with ACSS2 and Weight Gain
 Glucose Intolerance Antibodies  >2 publications with ACSS2 and Glucose Intolerance
 Breast Neoplasms Antibodies  >1 publications with ACSS2 and Breast Neoplasms
 Carcinoma, Hepatocellular Antibodies  >1 publications with ACSS2 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >1 publications with ACSS2 and Liver Neoplasms
 Liver Diseases Antibodies  >1 publications with ACSS2 and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >7 publications with ACSS2 and Blood
 Liver Antibodies  >5 publications with ACSS2 and Liver
 Connective Tissue Antibodies  >3 publications with ACSS2 and Connective Tissue
 Heart Antibodies  >2 publications with ACSS2 and Heart
 Embryonic Tissue Antibodies  >1 publications with ACSS2 and Embryonic Tissue
 Mammary Gland Antibodies  >1 publications with ACSS2 and Mammary Gland
 Kidney Antibodies  >1 publications with ACSS2 and Kidney
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