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ADCY10 elisa kit :: Goat Adenylate Cyclase 10, Soluble ELISA Kit

Scan QR to view Datasheet Catalog #    MBS096399 ADCY10 elisa kit
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Adenylate Cyclase 10, Soluble (ADCY10), ELISA Kit

 Also Known As   

Goat Adenylate Cyclase 10, Soluble ELISA Kit

 Product Gene Name   

ADCY10 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    143870
 3D Structure    ModBase 3D Structure for Q96PN6
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 Species Reactivity    Goat
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ADCY10 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ADCY10 purchase    MBS096399 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Adenylate Cyclase 10, Soluble (ADCY10) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ADCY10. The ELISA analytical biochemical technique of the MBS096399 kit is based on ADCY10 antibody-ADCY10 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ADCY10 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ADCY10. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for ADCY10. It may not necessarily be applicable to this product.
 NCBI GI #    209976994
 NCBI GeneID    55811
 NCBI Accession #    NP_060887.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_018417.5 [Other Products]
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 UniProt Primary Accession #    Q96PN6 [Other Products]
 UniProt Secondary Accession #    O95558; Q5R329; Q5R330; Q8WXV4; Q9NNX0; B4DZF0; F5GWS5 [Other Products]
 UniProt Related Accession #    Q96PN6 [Other Products]
 Molecular Weight    187,149 Da
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 NCBI Official Full Name    adenylate cyclase type 10 isoform 1
 NCBI Official Synonym Full Names    adenylate cyclase 10 (soluble)
 NCBI Official Symbol    ADCY10 [Similar Products]
 NCBI Official Synonym Symbols   
SAC; HCA2; SACI; Sacy; hsAC
[Similar Products]
 NCBI Protein Information    adenylate cyclase type 10; AH-related protein; ATP pyrophosphate-lyase; 3',5'-cyclic AMP synthetase; germ cell soluble adenylyl cyclase; testicular soluble adenylyl cyclase (SAC)
 UniProt Protein Name    Adenylate cyclase type 10
 UniProt Synonym Protein Names   
AH-related protein; Adenylate cyclase homolog; Germ cell soluble adenylyl cyclase; hsAC; sAC; Testicular soluble adenylyl cyclase
 Protein Family    Adenylate cyclase
 UniProt Gene Name    ADCY10 [Similar Products]
 UniProt Synonym Gene Names    SAC; hsAC; sAC [Similar Products]
 UniProt Entry Name    ADCYA_HUMAN
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 NCBI Summary for ADCY10    The protein encoded by this gene belongs to a distinct class of adenylyl cyclases that is soluble and insensitive to G protein or forskolin regulation. Activity of this protein is regulated by bicarbonate. Variation at this gene has been observed in patients with absorptive hypercalciuria. Alternatively spliced transcript variants encoding different isoforms have been observed. There is a pseudogene of this gene on chromosome 6. [provided by RefSeq, Jul 2014]
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 UniProt Comments for ADCY10    SAC: Soluble adenylyl cyclase that has a critical role in mammalian spermatogenesis. Produces the cAMP which mediates in part the cAMP-responsive nuclear factors indispensable for maturation of sperm in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. May be the bicarbonate sensor. Involved in ciliary beat regulation. Genetic variations in ADCY10 are a cause of susceptibility to hypercalciuria absorptive type 2 (HCA2). Absorptive hypercalciuria is a common type of hypercalciuria, a condition characterized by excessive urinary calcium excretion. Absorptive hypercalciuria is due to gastrointestinal hyperabsorption of calcium and is a frequent cause of calcium oxalate nephrolithiasis. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC; Nucleotide Metabolism - purine; Lyase; Adenylyl cyclase

Chromosomal Location of Human Ortholog: 1q24

Cellular Component: growth cone; cytoskeleton; cell soma; apical part of cell; axon; perinuclear region of cytoplasm; dendrite; cytoplasm; plasma membrane; cytosol

Molecular Function: manganese ion binding; magnesium ion binding; ATP binding; ATPase binding; adenylate cyclase activity

Biological Process: positive regulation of apoptosis; spermatogenesis; cAMP biosynthetic process

Disease: Hypercalciuria, Absorptive, 2
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 Research Articles on ADCY10    1. sAC is a regulator of gene expression involved in aldosterone signaling and an important regulator of endothelial stiffness.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ADCY10 elisa kitPathways associated with ADCY10 elisa kit
 Reference Product  PubMed Publications
 PDE4D elisa kit  >1 publications with ADCY10 and PDE4D
 PDE8A elisa kit  >1 publications with ADCY10 and PDE8A
 PDE4A elisa kit  >1 publications with ADCY10 and PDE4A
 Products by Pathway  Pathway Diagram
 Circadian Entrainment Pathway antibodies  Circadian Entrainment Pathway Diagram
 Circadian Entrainment Pathway antibodies  Circadian Entrainment Pathway Diagram
 Endothelin Pathway antibodies  Endothelin Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 CAMP Signaling Pathway antibodies  CAMP Signaling Pathway Diagram
 CAMP Signaling Pathway antibodies  CAMP Signaling Pathway Diagram
Diseases associated with ADCY10 elisa kitOrgans/Tissues associated with ADCY10 elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >1 publications with ADCY10 and Nervous System Diseases
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >5 publications with ADCY10 and Testis
 Eye Antibodies  >2 publications with ADCY10 and Eye
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