NP_001019815.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
38,508 Da
NCBI Official Full Name
chemokine XC receptor 1
NCBI Official Synonym Full Names
chemokine (C motif) receptor 1
NCBI Official Synonym Symbols
NCBI Protein Information
chemokine XC receptor 1; lymphotactin receptor; XC chemokine receptor 1; G protein-coupled receptor 5; G-protein coupled receptor 5; chemokine (C motif) XC receptor 1
UniProt Protein Name
Chemokine XC receptor 1
UniProt Synonym Protein Names
G-protein coupled receptor 5; Lymphotactin receptor; XC chemokine receptor 1
UniProt Synonym Gene Names
UniProt Entry Name
XCR1_HUMAN
NCBI Summary for XCL2
The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for XCL2
XCR1: Receptor for chemokines SCYC1 and SCYC2. Subsequently transduces a signal by increasing the intracellular calcium ions level. Belongs to the G-protein coupled receptor 1 family.
Protein type: Motility/polarity/chemotaxis; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1
Chromosomal Location of Human Ortholog: 3p21.3
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: chemokine receptor activity
Biological Process: G-protein signaling, coupled to cyclic nucleotide second messenger; G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; release of sequestered calcium ion into cytosol; chemotaxis; inflammatory response
Research Articles on XCL2
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Products associated with XCL2 elisa kit
Pathways associated with XCL2 elisa kit
Diseases associated with XCL2 elisa kit
Organs/Tissues associated with XCL2 elisa kit
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