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CRH-R elisa kit :: Goat Corticotropin Releasing Hormone Receptor ELISA Kit

Scan QR to view Datasheet Catalog #    MBS746547 CRH-R elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Corticotropin Releasing Hormone Receptor (CRH-R), ELISA Kit

 Also Known As   

Goat Corticotropin Releasing Hormone Receptor ELISA Kit

 Product Gene Name   

CRH-R elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    122561
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 Species Reactivity    Goat
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CRH-R elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CRH-R purchase    MBS746547 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Corticotropin Releasing Hormone Receptor (CRH-R) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CRH-R. The ELISA analytical biochemical technique of the MBS746547 kit is based on CRH-R antibody-CRH-R antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CRH-R antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CRH-R. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for CRH-R elisa kit    Signal Transduction
NCBI/Uniprot data below describe general gene information for CRH-R. It may not necessarily be applicable to this product.
 NCBI GI #    372466597
 NCBI GeneID    1394
 NCBI Accession #    NP_001243228.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001256299.1 [Other Products]
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 UniProt Secondary Accession #    Q13008; Q4QRJ1; Q9UK64; B4DIE9 [Other Products]
 UniProt Related Accession #    P34998 [Other Products]
 Molecular Weight    28,122 Da
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 NCBI Official Full Name    corticotropin-releasing factor receptor 1 isoform 5
 NCBI Official Synonym Full Names    corticotropin releasing hormone receptor 1
 NCBI Official Symbol    CRHR1 [Similar Products]
 NCBI Official Synonym Symbols   
CRF1; CRHR; CRF-R; CRFR1; CRF-R1; CRFR-1; CRH-R1; CRHR1L; CRHR1f; CRF-R-1; CRH-R-1; CRH-R1h
[Similar Products]
 NCBI Protein Information    corticotropin-releasing factor receptor 1; CRH receptor 1 variant B; seven transmembrane helix receptor; corticotropin-releasing hormone receptor 1; corticotropin-releasing factor type 1 receptor; corticotropin releasing hormone receptor variant 1e; corticotropin releasing hormone receptor variant 1g
 UniProt Protein Name    Corticotropin-releasing factor receptor 1
 UniProt Synonym Protein Names   
Corticotropin-releasing hormone receptor 1; CRH-R-1; CRH-R1
 UniProt Gene Name    CRHR1 [Similar Products]
 UniProt Synonym Gene Names    CRFR; CRFR1; CRHR; CRF-R-1; CRF-R1; CRFR-1; CRH-R-1; CRH-R1 [Similar Products]
 UniProt Entry Name    CRFR1_HUMAN
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 NCBI Summary for CRH-R    This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants, one of which represents a read-through transcript with the neighboring gene MGC57346. [provided by RefSeq, Jan 2012]
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 UniProt Comments for CRH-R    CRF-R1: a G-protein coupled receptor that specifically binds corticotropin-releasing hormone, a potent mediator of endocrine, autonomic, behavioral, and immune responses to stress. Four splice-variant isoforms have been described.

Protein type: Membrane protein, multi-pass; GPCR, family 2; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17q21.31

Cellular Component: multivesicular body; cell soma; apical part of cell; integral to plasma membrane; dendrite; plasma membrane; integral to membrane; trans-Golgi network; intrinsic to plasma membrane; vesicle

Molecular Function: protein binding; corticotropin-releasing hormone binding; corticotropin-releasing hormone receptor activity; protein complex binding; G-protein alpha-subunit binding; corticotrophin-releasing factor receptor activity

Biological Process: fear response; hypothalamus development; hormone-mediated signaling; adrenal gland development; adenylate cyclase activation; positive regulation of mast cell degranulation; female pregnancy; behavioral response to ethanol; memory; general adaptation syndrome, behavioral process; behavioral response to pain; elevation of cytosolic calcium ion concentration; epithelial cell differentiation; adrenocorticotropin hormone secretion; behavioral response to cocaine; neuropeptide signaling pathway; negative regulation of epinephrine secretion; response to hypoxia; visual learning; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); immune response; parturition; response to electrical stimulus
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 Research Articles on CRH-R    1. The receptors' binding specificity and structural studies were performed using full-length human CRFR1alpha and mouse CRFR2beta as well as fragments lacking the N-terminal extracellular domain.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CRH-R elisa kitPathways associated with CRH-R elisa kit
 Reference Product  PubMed Publications
 CRH elisa kit  >169 publications with CRH-R and CRH
 POMC elisa kit  >30 publications with CRH-R and POMC
 CRHBP elisa kit  >18 publications with CRH-R and CRHBP
 UCN elisa kit  >17 publications with CRH-R and UCN
 UCN2 elisa kit  >7 publications with CRH-R and UCN2
 UCN3 elisa kit  >6 publications with CRH-R and UCN3
 CREB1 elisa kit  >2 publications with CRH-R and CREB1
 CALM1 elisa kit  >1 publications with CRH-R and CALM1
 SLC2A1 elisa kit  >1 publications with CRH-R and SLC2A1
 TAC1 elisa kit  >1 publications with CRH-R and TAC1
 Products by Pathway  Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 Corticotropin-releasing Hormone Pathway antibodies  Corticotropin-releasing Hormone Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class B Secretin-like Pathway antibodies  GPCRs, Class B Secretin-like Pathway Diagram
 Long-term Depression Pathway antibodies  Long-term Depression Pathway Diagram
 Long-term Depression Pathway antibodies  Long-term Depression Pathway Diagram
 Myometrial Relaxation And Contraction Pathways antibodies  Myometrial Relaxation And Contraction Pathways Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
Diseases associated with CRH-R elisa kitOrgans/Tissues associated with CRH-R elisa kit
 Disease Name  Pubmed Publications
 Anxiety Disorders Antibodies  >39 publications with CRH-R and Anxiety Disorders
 Depressive Disorder Antibodies  >35 publications with CRH-R and Depressive Disorder
 Depressive Disorder, Major Antibodies  >25 publications with CRH-R and Depressive Disorder, Major
 Nervous System Diseases Antibodies  >23 publications with CRH-R and Nervous System Diseases
 Disease Models, Animal Antibodies  >17 publications with CRH-R and Disease Models, Animal
 Lung Diseases Antibodies  >16 publications with CRH-R and Lung Diseases
 Brain Diseases Antibodies  >15 publications with CRH-R and Brain Diseases
 Cardiovascular Diseases Antibodies  >10 publications with CRH-R and Cardiovascular Diseases
 Anoxia Antibodies  >7 publications with CRH-R and Anoxia
 Movement Disorders Antibodies  >7 publications with CRH-R and Movement Disorders
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >147 publications with CRH-R and Brain
 Embryonic Tissue Antibodies  >5 publications with CRH-R and Embryonic Tissue
 Ovary Antibodies  >3 publications with CRH-R and Ovary
 Eye Antibodies  >2 publications with CRH-R and Eye
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