Q07108.1
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
22,559 Da
NCBI Official Full Name
Early activation antigen CD69
NCBI Official Synonym Full Names
CD69 molecule
NCBI Official Synonym Symbols
AIM; EA1; MLR-3; CLEC2C; GP32/28; BL-AC/P26 [Similar Products]
NCBI Protein Information
early activation antigen CD69; leukocyte surface antigen Leu-23; early T-cell activation antigen p60; early lymphocyte activation antigen; activation inducer molecule (AIM/CD69); C-type lectin domain family 2, member C; CD69 antigen (p60, early T-cell activation antigen)
UniProt Protein Name
Early activation antigen CD69
UniProt Synonym Protein Names
Activation inducer molecule; AIM; BL-AC/P26; C-type lectin domain family 2 member C; EA1; Early T-cell activation antigen p60; GP32/28; Leukocyte surface antigen Leu-23; MLR-3
UniProt Synonym Gene Names
UniProt Entry Name
CD69_HUMAN
NCBI Summary for EMA
This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. [provided by RefSeq, Aug 2011]
UniProt Comments for EMA
Function: Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.
Subunit structure: Homodimer; disulfide-linked. Ref.6 Ref.7 Ref.8
Subcellular location: Membrane; Single-pass type II membrane protein.
Tissue specificity: Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets.
Developmental stage: Earliest inducible cell surface glycoprotein acquired during lymphoid activation.
Induction: By antigens, mitogens or activators of PKC on the surface of T and B-lymphocytes. By interaction of IL-2 with the p75 IL-2R on the surface of NK cells.
Post-translational modification: Constitutive Ser/Thr phosphorylation in both mature thymocytes and activated T-lymphocytes.
Sequence similarities: Contains 1 C-type lectin domain.
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Products associated with EMA elisa kit
Diseases associated with EMA elisa kit
Organs/Tissues associated with EMA elisa kit
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