NP_003025.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
40,519 Da
NCBI Official Full Name
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase
NCBI Official Synonym Full Names
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
NCBI Official Synonym Symbols
GD3S; SIAT8; SIAT8A; SIAT8-A; ST8SiaI [Similar Products]
NCBI Protein Information
alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; ganglioside GD3 synthase; ganglioside GT3 synthase; sialytransferase St8Sia I; sialyltransferase St8Sia I; alpha-2,8-sialyltransferase 8A; disialoganglioside (GD3) synthase; ganglioside-specific alpha-2,8-polysialyltransferase; sialyltransferase 8 (alpha-N-acetylneuraminate: alpha-2,8-sialytransferase, GD3 synthase) A; sialyltransferase 8A (alpha-N-acetylneuraminate: alpha-2,8-sialyltransferase, GD3 synthase)
UniProt Protein Name
Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase
UniProt Synonym Protein Names
Alpha-2,8-sialyltransferase 8A; Ganglioside GD3 synthase; Ganglioside GT3 synthase; Sialyltransferase 8A; SIAT8-A; Sialyltransferase St8Sia I
UniProt Synonym Gene Names
UniProt Entry Name
SIA8A_HUMAN
NCBI Summary for GM3
Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. [provided by RefSeq, Jul 2008]
UniProt Comments for GM3
ST8SIA1: Involved in the production of gangliosides GD3 and GT3 from GM3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid. Belongs to the glycosyltransferase 29 family.
Protein type: Transferase; Glycan Metabolism - glycosphingolipid biosynthesis - ganglio series; Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; Glycan Metabolism - glycosphingolipid biosynthesis - globo series; Membrane protein, integral; EC 2.4.99.8
Chromosomal Location of Human Ortholog: 12p12.1-p11.2
Cellular Component: Golgi membrane; integral to membrane; integral to Golgi membrane
Molecular Function: alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity; sialyltransferase activity
Biological Process: cellular protein metabolic process; glycosphingolipid biosynthetic process; dolichol-linked oligosaccharide biosynthetic process; positive regulation of cell proliferation; carbohydrate metabolic process; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification
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Pathways associated with GM3 elisa kit
Diseases associated with GM3 elisa kit
Organs/Tissues associated with GM3 elisa kit
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