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GC elisa kit :: Goat Glucagon ELISA Kit

Scan QR to view Datasheet Catalog #    MBS007669 GC elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Glucagon (GC), ELISA Kit

 Also Known As   

Goat Glucagon ELISA Kit

 Product Gene Name   

GC elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 2; NC_000002.11 (162999379..163008914, complement). Location: 2q36-q37
 OMIM    138030
 3D Structure    ModBase 3D Structure for P01275
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 Species Reactivity    Goat
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of GC elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for GC purchase    MBS007669 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Glucagon (GC) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GC. The ELISA analytical biochemical technique of the MBS007669 kit is based on GC antibody-GC antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GC antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GC. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for GC. It may not necessarily be applicable to this product.
 NCBI GI #    4503945
 NCBI GeneID    2641
 NCBI Accession #    NP_002045.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002054.4 [Other Products]
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 UniProt Primary Accession #    P01275 [Other Products]
 UniProt Secondary Accession #    Q53TP6; A6NN65 [Other Products]
 UniProt Related Accession #    P01275 [Other Products]
 Molecular Weight    20,909 Da
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 NCBI Official Full Name    glucagon preproprotein
 NCBI Official Synonym Full Names    glucagon
 NCBI Official Symbol    GCG [Similar Products]
 NCBI Official Synonym Symbols   
GLP1; GLP2; GRPP
[Similar Products]
 NCBI Protein Information    glucagon; preproglucagon; glucagon-like peptide 1; glucagon-like peptide 2; glicentin-related polypeptide
 UniProt Protein Name    Glucagon
 UniProt Synonym Protein Names   
Incretin hormone
 Protein Family    Glucagon
 UniProt Gene Name    GCG [Similar Products]
 UniProt Synonym Gene Names    GRPP; OXM; OXY; GLP-1; GLP-1(7-37); GLP-1(7-36); GLP-2 [Similar Products]
 UniProt Entry Name    GLUC_HUMAN
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 NCBI Summary for GC    The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008]
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 UniProt Comments for GC    GCG: Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon release is stimulated by hypoglycemia and inhibited by hyperglycemia, insulin, and somatostatin. GLP-1 and GLP-2 are induced in response to nutrient ingestion. Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP1 and GLP2 are also secreted in selected neurons in the brain. Belongs to the glucagon family.

Protein type: Secreted, signal peptide; Secreted; Hormone

Chromosomal Location of Human Ortholog: 2q36-q37

Cellular Component: extracellular space; endoplasmic reticulum lumen; plasma membrane; extracellular region

Molecular Function: identical protein binding; protein binding; hormone activity; glucagon receptor binding; receptor binding

Biological Process: positive regulation of protein binding; positive regulation of histone H3-K4 methylation; signal transduction; positive regulation of peptidyl-serine phosphorylation; response to starvation; G-protein signaling, coupled to cAMP nucleotide second messenger; cell proliferation; G-protein coupled receptor protein signaling pathway; cellular protein metabolic process; positive regulation of protein kinase activity; positive regulation of cAMP biosynthetic process; energy reserve metabolic process; feeding behavior; regulation of insulin secretion; negative regulation of apoptosis
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 Research Articles on GC    1. With G9a and GLP1 as representative Protein methyltransferases (PMTs), it demonstrated the use of methionine analogues, a MAT variant and engineered PMTs for substrate labeling in vitro and genome-wide chromatin modifications within living cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with GC elisa kitPathways associated with GC elisa kit
 Reference Product  PubMed Publications
 GLP1R elisa kit  >5 publications with GC and GLP1R
 GCGR elisa kit  >4 publications with GC and GCGR
 GLP2R elisa kit  >3 publications with GC and GLP2R
 FOXA2 elisa kit  >2 publications with GC and FOXA2
 GIPR elisa kit  >1 publications with GC and GIPR
 SCT elisa kit  >1 publications with GC and SCT
 Products by Pathway  Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 FOXA1 Transcription Factor Network Pathway antibodies  FOXA1 Transcription Factor Network Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Glucagon Signaling In Metabolic Regulation Pathway antibodies  Glucagon Signaling In Metabolic Regulation Pathway Diagram
 Glucagon-type Ligand Receptors Pathway antibodies  Glucagon-type Ligand Receptors Pathway Diagram
 Incretin Synthesis, Secretion, And Inactivation Pathway antibodies  Incretin Synthesis, Secretion, And Inactivation Pathway Diagram
Diseases associated with GC elisa kitOrgans/Tissues associated with GC elisa kit
 Disease Name  Pubmed Publications
 Muscular Diseases Antibodies  >70 publications with GC and Muscular Diseases
 Diabetes Mellitus Antibodies  >32 publications with GC and Diabetes Mellitus
 Vascular Diseases Antibodies  >15 publications with GC and Vascular Diseases
 Obesity Antibodies  >12 publications with GC and Obesity
 Kidney Diseases Antibodies  >11 publications with GC and Kidney Diseases
 Insulin Resistance Antibodies  >10 publications with GC and Insulin Resistance
 Hyperglycemia Antibodies  >8 publications with GC and Hyperglycemia
 Heart Diseases Antibodies  >8 publications with GC and Heart Diseases
 Drug Toxicity Antibodies  >7 publications with GC and Drug Toxicity
 Liver Diseases Antibodies  >7 publications with GC and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >28 publications with GC and Pancreas
 Intestine Antibodies  >13 publications with GC and Intestine
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