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GLUT-1 elisa kit :: Goat Glucose Transporter 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS005407 GLUT-1 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Glucose Transporter 1 (GLUT-1), ELISA Kit

 Also Known As   

Goat Glucose Transporter 1 ELISA Kit

 Product Gene Name   

GLUT-1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 4; NC_000070.6 (119108745..119137330). Location: 4 D2.1; 4 55.34 cM
 3D Structure    ModBase 3D Structure for P17809
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 Species Reactivity    Goat
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of GLUT-1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for GLUT-1 purchase    MBS005407 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Glucose Transporter 1 (GLUT-1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GLUT-1. The ELISA analytical biochemical technique of the MBS005407 kit is based on GLUT-1 antibody-GLUT-1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GLUT-1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GLUT-1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for GLUT-1. It may not necessarily be applicable to this product.
 NCBI GI #    312593
 NCBI GeneID    20525
 NCBI Accession #    CAA49367.1 [Other Products]
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 UniProt Primary Accession #    P17809 [Other Products]
 UniProt Secondary Accession #    Q61608; Q6GTI3 [Other Products]
 UniProt Related Accession #    P17809 [Other Products]
 Molecular Weight    53,985 Da
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 NCBI Official Full Name    Glut-1
 NCBI Official Synonym Full Names    solute carrier family 2 (facilitated glucose transporter), member 1
 NCBI Official Symbol    Slc2a1 [Similar Products]
 NCBI Official Synonym Symbols   
Glut1; Glut-1
[Similar Products]
 NCBI Protein Information    solute carrier family 2, facilitated glucose transporter member 1; GT1; solute carrier family 2, member 1; glucose transporter type 1, erythrocyte/brain
 UniProt Protein Name    Solute carrier family 2, facilitated glucose transporter member 1
 UniProt Synonym Protein Names   
Glucose transporter type 1, erythrocyte/brain
 Protein Family    Glucose transporter
 UniProt Gene Name    Slc2a1 [Similar Products]
 UniProt Synonym Gene Names    Glut-1; Glut1; GLUT-1; GT1 [Similar Products]
 UniProt Entry Name    GTR1_MOUSE
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 UniProt Comments for GLUT-1    GLUT1: an integral membrane protein that plays an important role in the glycolytic pathway by serving as a uniporter for glucose. One of 13 members of the human equilibrative glucose transport protein family. Transports a wide range of aldoses, including both pentoses and hexoses, and dehydroascorbic acid. Shown to transport water against an osmotic gradient. A receptor for the Human T-cell Leukemia virus (HTLV). Plays a role in the constitutive or basal uptake of glucose. Expressed at highest levels in proliferating cells of the early developing embryo, cells forming the blood tissue barriers, in human erythrocytes, astrocytes and in cardiac muscle. GLUT1 and GLUT3 are both essential for normal embryonic development. Is practically the only member of the GLUT family expressed on human red blood cells, where it comprises 10 - 20% of the integral membrane protein content. Several glycolytic proteins including the transporters GLUT1 and GLUT3, as well as multiple enzymes including HK2, PFKL, LDHA, ALDOA, ALDOC, PGK1, ENO1, PKM2, CA9 and PFKFB3 are induced in cancer cells by HIF-1 alpha. Polyps from Peutz-Jeghers patients exhibit up-regulated mTORC1 signaling, HIF-1alpha, and GLUT1 levels. Defects in GLUT1 are the cause of autosomal dominant GLUT1 deficiency syndrome, a blood-brain barrier glucose transport defect characterized by infantile seizures, delayed development, and acquired microcephaly. Defects also cause dystonia type 18, an exercise-induced paroxysmal dystonia/dyskinesia. Cytochalasin B binds to its inner surface, inhibiting its glucose transport activity with an IC50 of 0.44 uM.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter; Transporter, SLC family

Cellular Component: cortical actin cytoskeleton; basolateral plasma membrane; integral to plasma membrane; integral to membrane; female pronucleus; intercellular junction; caveola; cytosol; lipid raft; membrane; cytoplasm; plasma membrane; midbody; intracellular; vesicle

Molecular Function: identical protein binding; xenobiotic transporter activity; D-glucose transmembrane transporter activity; protein binding; protein self-association; dehydroascorbic acid transporter activity; transporter activity; glucose transmembrane transporter activity; transmembrane transporter activity; substrate-specific transmembrane transporter activity; kinase binding

Biological Process: cellular response to glucose starvation; transport; carbohydrate transport; protein complex assembly; xenobiotic transport; glucose transport; transmembrane transport
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 Research Articles on GLUT-1    1. Access to a running wheel for 48h induced plastic changes in the expression of astrocyte GLUT1. A significant increase was found only in motor cortex, though other motor related areas showed a similar trend(sensorimotor cortex, striatum and cerebellum).
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with GLUT-1 elisa kitDiseases associated with GLUT-1 elisa kit
 Products by Pathway  Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Facilitative Na+-independent Glucose Transporters Pathway antibodies  Facilitative Na+-independent Glucose Transporters Pathway Diagram
 Glucose Transport Pathway antibodies  Glucose Transport Pathway Diagram
 Glycolysis And Gluconeogenesis Pathway antibodies  Glycolysis And Gluconeogenesis Pathway Diagram
 HIF-1 Signaling Pathway antibodies  HIF-1 Signaling Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >420 publications with GLUT-1 and Neoplasms
 Adenocarcinoma Antibodies  >105 publications with GLUT-1 and Adenocarcinoma
 Cardiovascular Diseases Antibodies  >105 publications with GLUT-1 and Cardiovascular Diseases
 Hyperglycemia Antibodies  >80 publications with GLUT-1 and Hyperglycemia
 Seizures Antibodies  >67 publications with GLUT-1 and Seizures
 Kidney Diseases Antibodies  >58 publications with GLUT-1 and Kidney Diseases
 Diabetes Mellitus, Type 2 Antibodies  >53 publications with GLUT-1 and Diabetes Mellitus, Type 2
 Breast Neoplasms Antibodies  >50 publications with GLUT-1 and Breast Neoplasms
 Liver Diseases Antibodies  >47 publications with GLUT-1 and Liver Diseases
 Necrosis Antibodies  >45 publications with GLUT-1 and Necrosis
Organs/Tissues associated with GLUT-1 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >584 publications with GLUT-1 and Blood
 Brain Antibodies  >384 publications with GLUT-1 and Brain
 Liver Antibodies  >114 publications with GLUT-1 and Liver
 Kidney Antibodies  >101 publications with GLUT-1 and Kidney
 Embryonic Tissue Antibodies  >100 publications with GLUT-1 and Embryonic Tissue
 Connective Tissue Antibodies  >72 publications with GLUT-1 and Connective Tissue
 Lung Antibodies  >53 publications with GLUT-1 and Lung
 Eye Antibodies  >44 publications with GLUT-1 and Eye
 Pancreas Antibodies  >38 publications with GLUT-1 and Pancreas
 Skin Antibodies  >34 publications with GLUT-1 and Skin
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