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ITGB2 elisa kit :: Goat Integrin beta-2 (ITGB2) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7226085 ITGB2 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Integrin beta-2 (ITGB2), ELISA Kit

 Also Known As   

Goat Integrin beta-2 (ITGB2) ELISA Kit

 Product Gene Name   

ITGB2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    600065
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 Species Reactivity    Goat
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ITGB2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ITGB2 purchase    MBS7226085 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Integrin beta-2 (ITGB2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ITGB2. The ELISA analytical biochemical technique of the MBS7226085 kit is based on ITGB2 antibody-ITGB2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ITGB2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ITGB2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for ITGB2 elisa kit    Immunology
NCBI/Uniprot data below describe general gene information for ITGB2. It may not necessarily be applicable to this product.
 NCBI GI #    89191865
 NCBI GeneID    3689
 NCBI Accession #    NP_000202.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000211.3 [Other Products]
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 UniProt Secondary Accession #    Q16418; Q53HS5; Q9UD72; B3KTS8; D3DSM1 [Other Products]
 UniProt Related Accession #    P05107 [Other Products]
 Molecular Weight    84,782 Da
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 NCBI Official Full Name    integrin beta-2
 NCBI Official Synonym Full Names    integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
 NCBI Official Symbol    ITGB2 [Similar Products]
 NCBI Official Synonym Symbols   
LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1
[Similar Products]
 NCBI Protein Information    integrin beta-2; integrin beta chain, beta 2; complement receptor C3 beta-subunit; complement receptor C3 subunit beta; leukocyte cell adhesion molecule CD18; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; cell surface adhesion glycoprotein LFA-1/CR3/P150,959 beta subunit precursor)
 UniProt Protein Name    Integrin beta-2
 UniProt Synonym Protein Names   
Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; Complement receptor C3 subunit beta; CD_antigen: CD18
 Protein Family    Integrin
 UniProt Gene Name    ITGB2 [Similar Products]
 UniProt Synonym Gene Names    CD18; MFI7 [Similar Products]
 UniProt Entry Name    ITB2_HUMAN
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 NCBI Summary for ITGB2    The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ITGB2    ITGB2: the integrin beta 2 subunit. Can combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Participates in cell adhesion as well as cell-surface mediated signaling. Defects are the cause of leukocyte adhesion deficiency type I (LAD1).

Protein type: Membrane protein, integral; Cell adhesion; Cell surface; Receptor, misc.; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: cell surface; membrane; plasma membrane; integrin complex; vesicle; receptor complex; lipid raft

Molecular Function: protein binding; protein heterodimerization activity; metal ion binding; protein complex binding; cell adhesion molecule binding; ICAM-3 receptor activity; glycoprotein binding; protein kinase binding

Biological Process: extracellular matrix organization and biogenesis; positive regulation of nitric oxide biosynthetic process; apoptosis; cell-matrix adhesion; natural killer cell activation; receptor clustering; activation of NF-kappaB transcription factor; regulation of cell shape; leukocyte adhesion; cell-cell signaling; cellular extravasation; cell adhesion; inflammatory response; regulation of peptidyl-tyrosine phosphorylation; toll-like receptor 4 signaling pathway; aging; integrin-mediated signaling pathway; neutrophil chemotaxis; regulation of immune response; activated T cell proliferation; leukocyte migration during inflammatory response; heterotypic cell-cell adhesion; positive regulation of angiogenesis; toll-like receptor signaling pathway; innate immune response; endothelial cell migration; blood coagulation; leukocyte migration

Disease: Leukocyte Adhesion Deficiency, Type I
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 Research Articles on ITGB2    1. circulating trisomy 12 CLL cells also have increased expression of the integrins CD11b, CD18, CD29, and ITGB7, and the adhesion molecule CD323.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ITGB2 elisa kitPathways associated with ITGB2 elisa kit
 Reference Product  PubMed Publications
 ITGAM elisa kit  >1636 publications with ITGB2 and ITGAM
 ITGAL elisa kit  >1089 publications with ITGB2 and ITGAL
 ICAM1 elisa kit  >878 publications with ITGB2 and ICAM1
 ITGAX elisa kit  >408 publications with ITGB2 and ITGAX
 ICAM2 elisa kit  >59 publications with ITGB2 and ICAM2
 ICAM3 elisa kit  >48 publications with ITGB2 and ICAM3
 ITGAD elisa kit  >13 publications with ITGB2 and ITGAD
 JAM3 elisa kit  >6 publications with ITGB2 and JAM3
 ITGA7 elisa kit  >1 publications with ITGB2 and ITGA7
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 CXCR3-mediated Signaling Events Pathway antibodies  CXCR3-mediated Signaling Events Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 HIF-1-alpha Transcription Factor Network Pathway antibodies  HIF-1-alpha Transcription Factor Network Pathway Diagram
Diseases associated with ITGB2 elisa kitOrgans/Tissues associated with ITGB2 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >910 publications with ITGB2 and Inflammation
 Necrosis Antibodies  >615 publications with ITGB2 and Necrosis
 Cardiovascular Diseases Antibodies  >402 publications with ITGB2 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >232 publications with ITGB2 and Disease Models, Animal
 Lung Diseases Antibodies  >219 publications with ITGB2 and Lung Diseases
 Leukocyte-Adhesion Deficiency Syndrome Antibodies  >165 publications with ITGB2 and Leukocyte-Adhesion Deficiency Syndrome
 Heart Diseases Antibodies  >129 publications with ITGB2 and Heart Diseases
 Leukocyte Disorders Antibodies  >114 publications with ITGB2 and Leukocyte Disorders
 Hypersensitivity Antibodies  >112 publications with ITGB2 and Hypersensitivity
 Atherosclerosis Antibodies  >72 publications with ITGB2 and Atherosclerosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3710 publications with ITGB2 and Blood
 Lung Antibodies  >374 publications with ITGB2 and Lung
 Bone Antibodies  >292 publications with ITGB2 and Bone
 Bone Marrow Antibodies  >262 publications with ITGB2 and Bone Marrow
 Heart Antibodies  >185 publications with ITGB2 and Heart
 Muscle Antibodies  >161 publications with ITGB2 and Muscle
 Liver Antibodies  >127 publications with ITGB2 and Liver
 Embryonic Tissue Antibodies  >123 publications with ITGB2 and Embryonic Tissue
 Kidney Antibodies  >104 publications with ITGB2 and Kidney
 Spleen Antibodies  >102 publications with ITGB2 and Spleen
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