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MEPE elisa kit :: Goat Matrix extracellular phosphoglycoprotein ELISA Kit

Scan QR to view Datasheet Catalog #    MBS735449 MEPE elisa kit
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Matrix extracellular phosphoglycoprotein (MEPE), ELISA Kit

 Also Known As   

Goat Matrix extracellular phosphoglycoprotein ELISA Kit

 Product Gene Name   

MEPE elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 4; NC_000004.11 (88742563..88767969). Location: 4q21.1
 OMIM    605912
 3D Structure    ModBase 3D Structure for Q9NQ76
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 Species Reactivity    Goat
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of MEPE elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for MEPE purchase    MBS735449 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Matrix extracellular phosphoglycoprotein (MEPE) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MEPE. The ELISA analytical biochemical technique of the MBS735449 kit is based on MEPE antibody-MEPE antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MEPE antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MEPE. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for MEPE elisa kit    Cell Biology
NCBI/Uniprot data below describe general gene information for MEPE. It may not necessarily be applicable to this product.
 NCBI GI #    118764291
 NCBI GeneID    56955
 NCBI Accession #    AAI28159.1 [Other Products]
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 UniProt Primary Accession #    Q9NQ76 [Other Products]
 UniProt Secondary Accession #    A1A4X9 [Other Products]
 UniProt Related Accession #    Q8NC19; Q9NQ76 [Other Products]
 Molecular Weight    58,419 Da
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 NCBI Official Full Name    Matrix extracellular phosphoglycoprotein
 NCBI Official Synonym Full Names    matrix extracellular phosphoglycoprotein
 NCBI Official Symbol    MEPE [Similar Products]
 NCBI Official Synonym Symbols   
OF45
[Similar Products]
 NCBI Protein Information    matrix extracellular phosphoglycoprotein; osteoblast/osteocyte factor 45; matrix, extracellular phosphoglycoprotein with ASARM motif (bone)
 UniProt Protein Name    Matrix extracellular phosphoglycoprotein
 UniProt Synonym Protein Names   
Osteoblast/osteocyte factor 45
 Protein Family    Matrix extracellular phosphoglycoprotein
 UniProt Gene Name    MEPE [Similar Products]
 UniProt Synonym Gene Names    OF45 [Similar Products]
 UniProt Entry Name    MEPE_HUMAN
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 NCBI Summary for MEPE    This gene encodes a secreted calcium-binding phosphoprotein that belongs to the small integrin-binding ligand, N-linked glycoprotein (SIBLING) family of proteins. Members of this family are components of the extracellular matrix of bone and dentin and regulate bone mineralization. Deficiency of a similar protein in mouse results in increased bone mass. Mice lacking this gene are resistant to aging-related trabecular bone loss. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
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 UniProt Comments for MEPE    MEPE: Promotes renal phosphate excretion and modulates mineralization. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4q21.1

Cellular Component: proteinaceous extracellular matrix

Molecular Function: protein binding; extracellular matrix structural constituent

Biological Process: negative regulation of bone mineralization; biomineral formation; regulation of bone remodeling; skeletal development
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 Research Articles on MEPE    1. MEPE or the MEPE-derived acidic serine aspartate-rich MEPE-associated motif peptide may contribute to decreased bone mineralization in Oncogenic osteomalacia patients.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with MEPE elisa kitOrgans/Tissues associated with MEPE elisa kit
 Disease Name  Pubmed Publications
 Hypophosphatemia Antibodies  >35 publications with MEPE and Hypophosphatemia
 Osteomalacia Antibodies  >31 publications with MEPE and Osteomalacia
 Rickets Antibodies  >30 publications with MEPE and Rickets
 Kidney Diseases Antibodies  >28 publications with MEPE and Kidney Diseases
 Bone Diseases, Metabolic Antibodies  >26 publications with MEPE and Bone Diseases, Metabolic
 Calcium Metabolism Disorders Antibodies  >26 publications with MEPE and Calcium Metabolism Disorders
 Phosphorus Metabolism Disorders Antibodies  >26 publications with MEPE and Phosphorus Metabolism Disorders
 Vitamin D Deficiency Antibodies  >22 publications with MEPE and Vitamin D Deficiency
 Hypophosphatemic Rickets, X-Linked Dominant Antibodies  >19 publications with MEPE and Hypophosphatemic Rickets, X-Linked Dominant
 Hypertension Antibodies  >8 publications with MEPE and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >108 publications with MEPE and Bone
 Brain Antibodies  >3 publications with MEPE and Brain
 Placenta Antibodies  >2 publications with MEPE and Placenta
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