NP_000906.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
12,722 Da
NCBI Official Full Name
oxytocin-neurophysin 1 preproprotein
NCBI Official Synonym Full Names
oxytocin/neurophysin I prepropeptide
NCBI Protein Information
oxytocin-neurophysin 1; neurophysin I; oxytocin, prepropeptide; oxytocin, prepro- (neurophysin I); oxytocin-neurophysin I, preproprotein
UniProt Protein Name
Oxytocin-neurophysin 1
UniProt Synonym Protein Names
Ocytocin
UniProt Synonym Gene Names
UniProt Entry Name
NEU1_HUMAN
NCBI Summary for OXT
This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. [provided by RefSeq, Dec 2013]
UniProt Comments for OXT
OXT: Neurophysin 1 specifically binds oxytocin. Belongs to the vasopressin/oxytocin family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 20p13
Cellular Component: extracellular space; extracellular region; terminal button; secretory granule
Molecular Function: oxytocin receptor binding; neurohypophyseal hormone activity
Biological Process: response to peptide hormone stimulus; male mating behavior; response to cAMP; heart development; response to glucocorticoid stimulus; drinking behavior; positive regulation of female receptivity; female pregnancy; signal transduction; response to estradiol stimulus; positive regulation of synaptic transmission; elevation of cytosolic calcium ion concentration; hyperosmotic salinity response; negative regulation of blood pressure; response to electrical stimulus; response to food; grooming behavior; response to retinoic acid; maternal behavior; eating behavior; regulation of heart rate; response to amphetamine; social behavior; response to cocaine; response to ether; sleep; memory; positive regulation of ossification; response to sucrose stimulus; positive regulation of synaptogenesis; positive regulation of prostaglandin secretion; regulation of sensory perception of pain; response to activity; sperm ejaculation; response to progesterone stimulus; positive regulation of blood pressure
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with OXT elisa kit
Pathways associated with OXT elisa kit
Diseases associated with OXT elisa kit
Organs/Tissues associated with OXT elisa kit
|