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C5B-9 elisa kit :: Goat Plasma Levels of Terminal Complement Complex ELISA Kit

Scan QR to view Datasheet Catalog #    MBS009749 C5B-9 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Plasma Levels of Terminal Complement Complex (C5B-9), ELISA Kit

 Also Known As   

Goat Plasma Levels of Terminal Complement Complex ELISA Kit

 Product Gene Name   

C5B-9 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    120940
 3D Structure    ModBase 3D Structure for P02748
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 Species Reactivity    Goat
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of C5B-9 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for C5B-9 purchase    MBS009749 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Plasma Levels of Terminal Complement Complex (C5B-9) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing C5B-9. The ELISA analytical biochemical technique of the MBS009749 kit is based on C5B-9 antibody-C5B-9 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect C5B-9 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, C5B-9. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for C5B-9. It may not necessarily be applicable to this product.
 NCBI GI #    4502511
 NCBI GeneID    735
 NCBI Accession #    NP_001728.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001737.3 [Other Products]
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 UniProt Primary Accession #    P02748 [Other Products]
 UniProt Related Accession #    P02748 [Other Products]
 Molecular Weight    63,173 Da
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 NCBI Official Full Name    complement component C9
 NCBI Official Synonym Full Names    complement component 9
 NCBI Official Symbol    C9 [Similar Products]
 NCBI Official Synonym Symbols   
C9D; ARMD15
[Similar Products]
 NCBI Protein Information    complement component C9
 UniProt Protein Name    Complement component C9
 UniProt Gene Name    C9 [Similar Products]
 UniProt Entry Name    CO9_HUMAN
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 NCBI Summary for C5B-9    This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency. [provided by RefSeq, Feb 2009]
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 UniProt Comments for C5B-9    C9: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC. Defects in C9 are a cause of complement component 9 deficiency (C9D). A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis. Belongs to the complement C6/C7/C8/C9 family.

Protein type: Apoptosis; Membrane protein, integral; Membrane protein, multi-pass; Extracellular matrix

Chromosomal Location of Human Ortholog: 5p14-p12

Cellular Component: membrane attack complex; integral to plasma membrane; cytoplasm; plasma membrane; extracellular region

Biological Process: complement activation, alternative pathway; regulation of complement activation; innate immune response; hemolysis by symbiont of host red blood cells; complement activation, classical pathway

Disease: Macular Degeneration, Age-related, 15; Complement Component 9 Deficiency
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 Research Articles on C5B-9    1. Borrelial CspA binds the human terminal complement components C7 and C9 and blocks assembly and membrane insertion of the terminal complement complex (TCC).
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with C5B-9 elisa kitDiseases associated with C5B-9 elisa kit
 Products by Pathway  Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Complement Activation, Classical Pathway antibodies  Complement Activation, Classical Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement Cascade Pathway antibodies  Complement Cascade Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Prion Diseases Pathway antibodies  Prion Diseases Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >139 publications with C5B-9 and Inflammation
 Kidney Diseases Antibodies  >129 publications with C5B-9 and Kidney Diseases
 Death Antibodies  >113 publications with C5B-9 and Death
 Necrosis Antibodies  >85 publications with C5B-9 and Necrosis
 Brain Diseases Antibodies  >76 publications with C5B-9 and Brain Diseases
 Fatty Liver Antibodies  >62 publications with C5B-9 and Fatty Liver
 Liver Diseases Antibodies  >49 publications with C5B-9 and Liver Diseases
 Heart Diseases Antibodies  >46 publications with C5B-9 and Heart Diseases
 Weight Loss Antibodies  >34 publications with C5B-9 and Weight Loss
 Immunologic Deficiency Syndromes Antibodies  >29 publications with C5B-9 and Immunologic Deficiency Syndromes
Organs/Tissues associated with C5B-9 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >249 publications with C5B-9 and Liver
 Muscle Antibodies  >175 publications with C5B-9 and Muscle
 Kidney Antibodies  >171 publications with C5B-9 and Kidney
 Placenta Antibodies  >12 publications with C5B-9 and Placenta
 Pancreas Antibodies  >12 publications with C5B-9 and Pancreas
 Uncharacterized Tissue Antibodies  >1 publications with C5B-9 and Uncharacterized Tissue
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