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PDCD6IP elisa kit :: Goat Programmed Cell Death Protein 6 Interacting Protein ELISA Kit

Scan QR to view Datasheet Catalog #    MBS085218 PDCD6IP elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Programmed Cell Death Protein 6 Interacting Protein (PDCD6IP), ELISA Kit

 Also Known As   

Goat Programmed Cell Death Protein 6 Interacting Protein ELISA Kit

 Product Gene Name   

PDCD6IP elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    608074
 3D Structure    ModBase 3D Structure for Q8WUM4
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 Species Reactivity    Goat
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PDCD6IP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PDCD6IP purchase    MBS085218 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Programmed Cell Death Protein 6 Interacting Protein (PDCD6IP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PDCD6IP. The ELISA analytical biochemical technique of the MBS085218 kit is based on PDCD6IP antibody-PDCD6IP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PDCD6IP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PDCD6IP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for PDCD6IP. It may not necessarily be applicable to this product.
 NCBI GI #    119584873
 NCBI GeneID    10015
 NCBI Accession #    EAW64469.1 [Other Products]
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 UniProt Primary Accession #    Q8WUM4 [Other Products]
 UniProt Secondary Accession #    Q6NUS1; Q9BX86; Q9NUN0; Q9P2H2; Q9UKL5; E9PFU1 [Other Products]
 UniProt Related Accession #    Q8WUM4 [Other Products]
 Molecular Weight    96,023 Da
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 NCBI Official Full Name    programmed cell death 6 interacting protein, isoform CRA_b
 NCBI Official Synonym Full Names    programmed cell death 6 interacting protein
 NCBI Official Symbol    PDCD6IP [Similar Products]
 NCBI Official Synonym Symbols   
AIP1; ALIX; HP95; DRIP4
[Similar Products]
 NCBI Protein Information    programmed cell death 6-interacting protein; PDCD6-interacting protein; ALG-2 interacting protein 1; ALG-2-interacting protein X; dopamine receptor interacting protein 4; apoptosis-linked gene 2-interacting protein X
 UniProt Protein Name    Programmed cell death 6-interacting protein
 UniProt Synonym Protein Names   
ALG-2-interacting protein 1; ALG-2-interacting protein X; Hp95
 Protein Family    Programmed cell death 6-interacting protein
 UniProt Gene Name    PDCD6IP [Similar Products]
 UniProt Synonym Gene Names    AIP1; ALIX; KIAA1375; PDCD6-interacting protein [Similar Products]
 UniProt Entry Name    PDC6I_HUMAN
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 NCBI Summary for PDCD6IP    This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. [provided by RefSeq, Jan 2012]
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 UniProt Comments for PDCD6IP    Alix: an adaptor protein that may regulate the function of receptor and cytoskeleton-associated tyrosine kinases. A class E vacuolar protein sorting (VPS) factor involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles. Fusion between endosomes and the vacuole will then target the cargo proteins to the vacuolar lumen. In case of infection, the HIV-1 virus directly takes advantage of its function for viral exocytosis and budding, via its interaction with HIV-1 p6 protein. May play a role in the regulation of both apoptosis and cell proliferation.

Protein type: Apoptosis; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 3p22.3

Cellular Component: focal adhesion; membrane; cytoplasm; melanosome; immunological synapse; microtubule organizing center; cytosol; vesicle

Molecular Function: protein binding; protein homodimerization activity; proteinase activated receptor binding; calcium-dependent protein binding; SH3 domain binding

Biological Process: protein transport; viral reproduction; cell separation during cytokinesis; apoptosis; viral infectious cycle; mitotic metaphase plate congression; nuclear organization and biogenesis
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 Research Articles on PDCD6IP    1. ALIX regulates these mammalian cell-specific cytokinesis, exosome release, and virus budding. [Review]
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with PDCD6IP elisa kitDiseases associated with PDCD6IP elisa kit
 Products by Pathway  Pathway Diagram
 Budding And Maturation Of HIV Virion Pathway antibodies  Budding And Maturation Of HIV Virion Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 HIV Infection Pathway antibodies  HIV Infection Pathway Diagram
 HIV Life Cycle Pathway antibodies  HIV Life Cycle Pathway Diagram
 Late Phase Of HIV Life Cycle Pathway antibodies  Late Phase Of HIV Life Cycle Pathway Diagram
 Uptake And Actions Of Bacterial Toxins Pathway antibodies  Uptake And Actions Of Bacterial Toxins Pathway Diagram
 Uptake And Function Of Anthrax Toxins Pathway antibodies  Uptake And Function Of Anthrax Toxins Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >11 publications with PDCD6IP and Neoplasms
 Adenocarcinoma Antibodies  >4 publications with PDCD6IP and Adenocarcinoma
 Immune System Diseases Antibodies  >4 publications with PDCD6IP and Immune System Diseases
 Kidney Diseases Antibodies  >4 publications with PDCD6IP and Kidney Diseases
 Carcinoma, Hepatocellular Antibodies  >2 publications with PDCD6IP and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >2 publications with PDCD6IP and Liver Neoplasms
 Liver Diseases Antibodies  >2 publications with PDCD6IP and Liver Diseases
 Breast Neoplasms Antibodies  >1 publications with PDCD6IP and Breast Neoplasms
 Edema Antibodies  >1 publications with PDCD6IP and Edema
 Prostatic Diseases Antibodies  >1 publications with PDCD6IP and Prostatic Diseases
Organs/Tissues associated with PDCD6IP elisa kit
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >10 publications with PDCD6IP and Kidney
 Brain Antibodies  >10 publications with PDCD6IP and Brain
 Blood Antibodies  >7 publications with PDCD6IP and Blood
 Nerve Antibodies  >5 publications with PDCD6IP and Nerve
 Muscle Antibodies  >4 publications with PDCD6IP and Muscle
 Lung Antibodies  >4 publications with PDCD6IP and Lung
 Heart Antibodies  >2 publications with PDCD6IP and Heart
 Liver Antibodies  >2 publications with PDCD6IP and Liver
 Vascular Antibodies  >1 publications with PDCD6IP and Vascular
 Skin Antibodies  >1 publications with PDCD6IP and Skin
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