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PTGS2 elisa kit :: Goat Prostaglandin G/H synthase 2 (PTGS2) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9333111 PTGS2 elisa kit
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 Product Name   

Prostaglandin G/H synthase 2 (PTGS2), ELISA Kit

 Also Known As   

Goat Prostaglandin G/H synthase 2, PTGS2 ELISA Kit

 Product Synonym Names    Goat Prostaglandin G/H synthase 2 (PTGS2) ELISA kit; COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2; cyclooxygenase 2b; prostaglandin G/H synthase and cyclooxygenase; prostaglandin-endoperoxide synthase 2; Prostaglandin G/H synthase 2 (PTGS2)
 Product Gene Name   

PTGS2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for P79208
 Species Reactivity    Goat
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PTGS2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PTGS2 purchase    MBS9333111 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Prostaglandin G/H synthase 2 (PTGS2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PTGS2. The ELISA analytical biochemical technique of the MBS9333111 kit is based on PTGS2 antibody-PTGS2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PTGS2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PTGS2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for PTGS2. It may not necessarily be applicable to this product.
 NCBI GI #    57164245
 NCBI GeneID    443460
 NCBI Accession #    NP_001009432.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001009432.1 [Other Products]
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 UniProt Primary Accession #    P79208 [Other Products]
 UniProt Related Accession #    P79208 [Other Products]
 Molecular Weight    68,969 Da
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 NCBI Official Full Name    prostaglandin G/H synthase 2
 NCBI Official Symbol    PTGS2 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    prostaglandin G/H synthase 2; COX-2; PHS II; PGH synthase 2; cyclooxygenase-2; prostaglandin H synthase-2; prostaglandin H2 synthase 2; cyclooxygenase, prostaglandin endoperoxide H synthase-2
 UniProt Protein Name    Prostaglandin G/H synthase 2
 UniProt Synonym Protein Names   
Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
 Protein Family    Prostaglandin G/H synthase
 UniProt Gene Name    PTGS2 [Similar Products]
 UniProt Synonym Gene Names    COX2; COX-2; PGH synthase 2; PGHS-2 [Similar Products]
 UniProt Entry Name    PGH2_SHEEP
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 UniProt Comments for PTGS2    Function: Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.1 PublicationManual assertion based on experiment in:Ref.3

Catalytic activity: Arachidonate + AH2 + 2 O2 = prostaglandin H2 + A + H2O.

Cofactor: Binds 1 heme B (iron-protoporphyrin IX) group per subunit
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 Research Articles on PTGS2    1. The expression of ERalpha, OTR, cPLA(2), COX-2, and PPARgamma in the cervix of the ewe during the estrous cycle.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with PTGS2 elisa kitOrgans/Tissues associated with PTGS2 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >5929 publications with PTGS2 and Neoplasms
 Inflammation Antibodies  >4840 publications with PTGS2 and Inflammation
 Carcinoma Antibodies  >2616 publications with PTGS2 and Carcinoma
 Necrosis Antibodies  >2288 publications with PTGS2 and Necrosis
 Cardiovascular Diseases Antibodies  >1935 publications with PTGS2 and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >1832 publications with PTGS2 and Nervous System Diseases
 Pain Antibodies  >1689 publications with PTGS2 and Pain
 Drug Toxicity Antibodies  >1538 publications with PTGS2 and Drug Toxicity
 Colorectal Neoplasms Antibodies  >1486 publications with PTGS2 and Colorectal Neoplasms
 Adenocarcinoma Antibodies  >1239 publications with PTGS2 and Adenocarcinoma
 Organ/Tissue Name  Pubmed Publications
 Female Genital Antibodies  >641 publications with PTGS2 and Female Genital
 Whole Body Antibodies  >54 publications with PTGS2 and Whole Body
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