NP_002723.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
40,434 Da
NCBI Official Full Name
cAMP-dependent protein kinase catalytic subunit gamma
NCBI Official Synonym Full Names
protein kinase, cAMP-dependent, catalytic, gamma
NCBI Official Synonym Symbols
NCBI Protein Information
cAMP-dependent protein kinase catalytic subunit gamma; PKA C-gamma; serine(threonine) protein kinase
UniProt Protein Name
cAMP-dependent protein kinase catalytic subunit gamma
UniProt Synonym Gene Names
UniProt Entry Name
KAPCG_HUMAN
NCBI Summary for PRKACG
Cyclic AMP-dependent protein kinase (PKA) consists of two catalytic subunits and a regulatory subunit dimer. This gene encodes the gamma form of its catalytic subunit. The gene is intronless and is thought to be a retrotransposon derived from the gene for the alpha form of the PKA catalytic subunit. [provided by RefSeq, Jul 2008]
UniProt Comments for PRKACG
PKACG: Phosphorylates a large number of substrates in the cytoplasm and the nucleus. A number of inactive tetrameric holoenzymes are produced by the combination of homo- or heterodimers of the different regulatory subunits associated with two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Testis specific. But important tissues such as brain and ovary have not been analyzed for the content of transcript. Activated by cAMP. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
Protein type: EC 2.7.11.11; Protein kinase, AGC; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; AGC group; PKA family
Chromosomal Location of Human Ortholog: 9q13
Cellular Component: cytosol
Molecular Function: cAMP-dependent protein kinase activity; ATP binding
Biological Process: epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; water transport; male gonad development; activation of protein kinase A; glucose metabolic process; pathogenesis; signal transduction; protein amino acid phosphorylation; gluconeogenesis; phospholipase C activation; carbohydrate metabolic process; triacylglycerol catabolic process; energy reserve metabolic process; renal water homeostasis; innate immune response; spermatogenesis; blood coagulation; transmembrane transport; regulation of insulin secretion
Disease: Mental Retardation, Autosomal Dominant 31
Research Articles on PRKACG
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Pathways associated with PRKACG elisa kit
Organs/Tissues associated with PRKACG elisa kit
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