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ANG elisa kit :: Goose Angiogenin ELISA Kit

Scan QR to view Datasheet Catalog #    MBS005822 ANG elisa kit
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 Product Name   

Angiogenin, ELISA Kit

 Also Known As   

Goose Angiogenin ELISA Kit

 Product Gene Name   

ANG elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 14; NC_000014.8 (21152336..21162345). Location: 14q11.1-q11.2
 OMIM    105850
 3D Structure    ModBase 3D Structure for P03950
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 Species Reactivity    Goose
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ANG elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ANG purchase    MBS005822 is a ready-to-use microwell, strip-or-full plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Angiogenin, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ANG. The ELISA analytical biochemical technique of the MBS005822 kit is based on ANG antibody-ANG antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ANG antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ANG. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for ANG. It may not necessarily be applicable to this product.
 NCBI GI #    4557313
 NCBI GeneID    283
 NCBI Accession #    NP_001136.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001145.4 [Other Products]
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 UniProt Primary Accession #    P03950 [Other Products]
 UniProt Secondary Accession #    Q05CV1; Q53X86; Q6P5T2; Q8WXE7 [Other Products]
 UniProt Related Accession #    P03950 [Other Products]
 Molecular Weight    16,550 Da
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 NCBI Official Full Name    angiogenin
 NCBI Official Synonym Full Names    angiogenin, ribonuclease, RNase A family, 5
 NCBI Official Symbol    ANG [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    angiogenin; RNase 5; ribonuclease 5; epididymis luminal protein 168
 UniProt Protein Name    Angiogenin
 UniProt Synonym Protein Names   
Ribonuclease 5
 Protein Family    Angiogenin
 UniProt Gene Name    ANG [Similar Products]
 UniProt Synonym Gene Names    RNASE5; RNase 5 [Similar Products]
 UniProt Entry Name    ANGI_HUMAN
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 NCBI Summary for ANG    The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ANG    ANG: May function as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo. Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9). ALS is a degenerative disorder of motor neurons in the cortex, brain stem and spinal cord. ALS is characterized by muscular weakness and atrophy. Belongs to the pancreatic ribonuclease family.

Protein type: EC 3.1.27.-; Motility/polarity/chemotaxis; Nucleolus; Extracellular matrix; Cell cycle regulation; RNA-binding; Secreted; Ribonuclease; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 14q11.1-q11.2

Cellular Component: angiogenin-PRI complex; extracellular space; growth cone; cell soma; nucleolus; basal lamina; nucleus

Molecular Function: heparin binding; rRNA binding; protein binding; copper ion binding; DNA binding; endonuclease activity; actin binding; peptide binding; receptor binding; ribonuclease activity

Biological Process: cell migration; negative regulation of smooth muscle cell proliferation; diacylglycerol biosynthetic process; activation of protein kinase B; response to hormone stimulus; activation of phospholipase A2; oocyte maturation; rRNA transcription; ovarian follicle development; homeostatic process; positive regulation of protein secretion; actin filament polymerization; phospholipase C activation; negative regulation of translation; response to hypoxia; cell communication; positive regulation of endothelial cell proliferation; angiogenesis; positive regulation of phosphorylation; placenta development

Disease: Amyotrophic Lateral Sclerosis 9
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 Research Articles on ANG    1. Angiogenin is up-regulated in the hypoxic environment of oral squamous cell carcinoma
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ANG elisa kitDiseases associated with ANG elisa kit
 Reference Product  PubMed Publications
 VEGFA elisa kit  >102 publications with ANG and VEGFA
 FUS elisa kit  >25 publications with ANG and FUS
 TARDBP elisa kit  >19 publications with ANG and TARDBP
 FST elisa kit  >3 publications with ANG and FST
 RNH1 elisa kit  >3 publications with ANG and RNH1
 TNFSF8 elisa kit  >1 publications with ANG and TNFSF8
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >3936 publications with ANG and Cardiovascular Diseases
 Hypertension Antibodies  >3585 publications with ANG and Hypertension
 Heart Diseases Antibodies  >1478 publications with ANG and Heart Diseases
 Neoplasms Antibodies  >1445 publications with ANG and Neoplasms
 Hypertrophy Antibodies  >1128 publications with ANG and Hypertrophy
 Disease Models, Animal Antibodies  >1111 publications with ANG and Disease Models, Animal
 Kidney Diseases Antibodies  >1078 publications with ANG and Kidney Diseases
 Inflammation Antibodies  >847 publications with ANG and Inflammation
 Fibrosis Antibodies  >776 publications with ANG and Fibrosis
 Necrosis Antibodies  >464 publications with ANG and Necrosis
Organs/Tissues associated with ANG elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >6961 publications with ANG and Blood
 Vascular Antibodies  >5395 publications with ANG and Vascular
 Muscle Antibodies  >3391 publications with ANG and Muscle
 Heart Antibodies  >3348 publications with ANG and Heart
 Kidney Antibodies  >3264 publications with ANG and Kidney
 Brain Antibodies  >2216 publications with ANG and Brain
 Lung Antibodies  >621 publications with ANG and Lung
 Liver Antibodies  >591 publications with ANG and Liver
 Bone Antibodies  >485 publications with ANG and Bone
 Eye Antibodies  >441 publications with ANG and Eye
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