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APOA5 elisa kit :: Goose Apolipoprotein A5 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS026006 APOA5 elisa kit
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 Product Name   

Apolipoprotein A5 (APOA5), ELISA Kit

 Also Known As   

Goose Apolipoprotein A5 ELISA Kit

 Product Gene Name   

APOA5 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 11; NC_000011.9 (116660086..116663136, complement). Location: 11q23
 OMIM    144650
 3D Structure    ModBase 3D Structure for Q6Q788
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 Species Reactivity    Goose
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of APOA5 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for APOA5 purchase    MBS026006 is a ready-to-use microwell, strip-or-full plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Apolipoprotein A5 (APOA5) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing APOA5. The ELISA analytical biochemical technique of the MBS026006 kit is based on APOA5 antibody-APOA5 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect APOA5 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, APOA5. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for APOA5. It may not necessarily be applicable to this product.
 NCBI GI #    262231737
 NCBI GeneID    116519
 NCBI Accession #    NP_001160070.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001166598.1 [Other Products]
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 UniProt Primary Accession #    Q6Q788 [Other Products]
 UniProt Secondary Accession #    Q3MIK6; Q6UWK9; Q9UBJ3; B0YIV9 [Other Products]
 UniProt Related Accession #    Q6Q788 [Other Products]
 Molecular Weight    41,213 Da
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 NCBI Official Full Name    apolipoprotein A-V
 NCBI Official Synonym Full Names    apolipoprotein A-V
 NCBI Official Symbol    APOA5 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    apolipoprotein A-V; apo-AV; apolipoprotein A5; regeneration-associated protein 3
 UniProt Protein Name    Apolipoprotein A-V
 UniProt Synonym Protein Names   
Apolipoprotein A5; Regeneration-associated protein 3
 Protein Family    Apolipoprotein
 UniProt Gene Name    APOA5 [Similar Products]
 UniProt Synonym Gene Names    RAP3; Apo-AV; ApoA-V [Similar Products]
 UniProt Entry Name    APOA5_HUMAN
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 NCBI Summary for APOA5    The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Oct 2009]
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 UniProt Comments for APOA5    APOA5: Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and a inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages. Interacts with GPIHBP1. Up-regulated by PPARA agonists, which are used clinically to lower serum TG (such as fibrates). Liver and plasma. Belongs to the apolipoprotein A1/A4/E family.

Protein type: Lipid-binding; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 11q23

Cellular Component: extracellular space; chylomicron; extracellular region

Molecular Function: heparin binding; enzyme binding; low-density lipoprotein receptor binding; cholesterol transporter activity; enzyme activator activity; cholesterol binding; phospholipid binding; phosphatidylcholine binding; lipid binding

Biological Process: positive regulation of fatty acid biosynthetic process; organ regeneration; response to hormone stimulus; neurite regeneration; lipoprotein metabolic process; positive regulation of lipid catabolic process; cholesterol efflux; cellular lipid metabolic process; lipid transport; cholesterol biosynthetic process; positive regulation of receptor-mediated endocytosis; phosphatidylcholine metabolic process; cholesterol homeostasis; reverse cholesterol transport; triacylglycerol metabolic process; regulation of cholesterol absorption; phospholipid efflux; acylglycerol homeostasis; tissue regeneration; triacylglycerol catabolic process; positive regulation of lipoprotein lipase activity

Disease: Hypertriglyceridemia, Familial; Hyperlipoproteinemia, Type V
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 Research Articles on APOA5    1. A meta-analysis of a Chinese population found that the APO A5 -1131T/C gene polymorphism was implied to be associated with coronary artery disease susceptibility.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with APOA5 elisa kitPathways associated with APOA5 elisa kit
 Reference Product  PubMed Publications
 APOC3 elisa kit  >60 publications with APOA5 and APOC3
 APOE elisa kit  >55 publications with APOA5 and APOE
 APOA1 elisa kit  >49 publications with APOA5 and APOA1
 APOB elisa kit  >36 publications with APOA5 and APOB
 APOA4 elisa kit  >26 publications with APOA5 and APOA4
 APOC2 elisa kit  >23 publications with APOA5 and APOC2
 APOA2 elisa kit  >4 publications with APOA5 and APOA2
 PPARA elisa kit  >3 publications with APOA5 and PPARA
 Products by Pathway  Pathway Diagram
 Chylomicron-mediated Lipid Transport Pathway antibodies  Chylomicron-mediated Lipid Transport Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Lipid Digestion, Mobilization, And Transport Pathway antibodies  Lipid Digestion, Mobilization, And Transport Pathway Diagram
 Lipoprotein Metabolism Pathway antibodies  Lipoprotein Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram
 PPARA Activates Gene Expression Pathway antibodies  PPARA Activates Gene Expression Pathway Diagram
 Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway antibodies  Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway Diagram
Diseases associated with APOA5 elisa kitOrgans/Tissues associated with APOA5 elisa kit
 Disease Name  Pubmed Publications
 Dyslipidemias Antibodies  >153 publications with APOA5 and Dyslipidemias
 Hypertriglyceridemia Antibodies  >141 publications with APOA5 and Hypertriglyceridemia
 Hyperlipidemias Antibodies  >135 publications with APOA5 and Hyperlipidemias
 Cardiovascular Diseases Antibodies  >123 publications with APOA5 and Cardiovascular Diseases
 Heart Diseases Antibodies  >73 publications with APOA5 and Heart Diseases
 Atherosclerosis Antibodies  >70 publications with APOA5 and Atherosclerosis
 Arteriosclerosis Antibodies  >50 publications with APOA5 and Arteriosclerosis
 Insulin Resistance Antibodies  >41 publications with APOA5 and Insulin Resistance
 Diabetes Mellitus, Type 2 Antibodies  >27 publications with APOA5 and Diabetes Mellitus, Type 2
 Liver Diseases Antibodies  >15 publications with APOA5 and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >43 publications with APOA5 and Liver
 Lung Antibodies  >1 publications with APOA5 and Lung
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