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AATF elisa kit :: Goose Apoptosis Antagonizing Transcription Factor ELISA Kit

Scan QR to view Datasheet Catalog #    MBS012147 AATF elisa kit
Unit / Price
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Apoptosis Antagonizing Transcription Factor (AATF), ELISA Kit

 Also Known As   

Goose Apoptosis Antagonizing Transcription Factor ELISA Kit

 Product Gene Name   

AATF elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 10; NC_005109.3 (71654744..71747166, complement). Location: 10q26
 3D Structure    ModBase 3D Structure for Q9QYW0
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 Species Reactivity    Goose
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of AATF elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for AATF purchase    MBS012147 is a ready-to-use microwell, strip-or-full plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Apoptosis Antagonizing Transcription Factor (AATF) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing AATF. The ELISA analytical biochemical technique of the MBS012147 kit is based on AATF antibody-AATF antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect AATF antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, AATF. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for AATF. It may not necessarily be applicable to this product.
 NCBI GI #    6114758
 NCBI GeneID    114512
 NCBI Accession #    CAB59426.1 [Other Products]
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 UniProt Primary Accession #    Q9QYW0 [Other Products]
 UniProt Related Accession #    Q9QYW0 [Other Products]
 Molecular Weight    59,497 Da
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 NCBI Official Full Name    AATF protein
 NCBI Official Synonym Full Names    apoptosis antagonizing transcription factor
 NCBI Official Symbol    Aatf [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    protein AATF; apoptosis-antagonizing transcription factor
 UniProt Protein Name    Protein AATF
 UniProt Synonym Protein Names   
Apoptosis-antagonizing transcription factor
 Protein Family    Protein
 UniProt Gene Name    Aatf [Similar Products]
 UniProt Entry Name    AATF_RAT
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 NCBI Summary for AATF    an apoptosis antagonizing nuclear phosphoprotein transcription factor [RGD, Feb 2006]
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 UniProt Comments for AATF    AATF: May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle progression. Also antagonizes PAWR mediated induction of aberrant amyloid peptide production in Alzheimer disease (presenile and senile dementia), although the molecular basis for this phenomenon has not been described to date. Belongs to the AATF family.

Protein type: RNA-binding; Transcription factor; Nucleolus

Cellular Component: Golgi apparatus; centrosome; focal adhesion; cytoplasm; nucleolus; nucleus

Molecular Function: protein domain specific binding; leucine zipper domain binding; tau protein binding; transcription factor activity

Biological Process: apoptosis; positive regulation of transcription, DNA-dependent; negative regulation of amyloid precursor protein biosynthetic process; regulation of mitotic cell cycle; ribosome biogenesis and assembly; positive regulation of transcription from RNA polymerase II promoter; negative regulation of superoxide release; cell adhesion; response to DNA damage stimulus; embryonic cleavage; negative regulation of apoptosis
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 Research Articles on AATF    1. Ectopic expression of AATF or a constitutively active form of AKT1 confers on cells resistance to ER stress-mediated cell death, whereas RNAi-mediated knockdown of AATF or AKT1 renders cells sensitive to ER stress.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with AATF elisa kitPathways associated with AATF elisa kit
 Reference Product  PubMed Publications
 Tsg101 elisa kit  >2 publications with AATF and Tsg101
 Maged1 elisa kit  >1 publications with AATF and Maged1
 Products by Pathway  Pathway Diagram
 Cell Death Signalling Via NRAGE, NRIF And NADE Pathway antibodies  Cell Death Signalling Via NRAGE, NRIF And NADE Pathway Diagram
 NRAGE Signals Death Through JNK Pathway antibodies  NRAGE Signals Death Through JNK Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signalling By NGF Pathway antibodies  Signalling By NGF Pathway Diagram
 P75 NTR Receptor-mediated Signalling Pathway antibodies  P75 NTR Receptor-mediated Signalling Pathway Diagram
Diseases associated with AATF elisa kitOrgans/Tissues associated with AATF elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >13 publications with AATF and Neoplasms
 Lymphoma Antibodies  >3 publications with AATF and Lymphoma
 Breast Neoplasms Antibodies  >2 publications with AATF and Breast Neoplasms
 Inflammation Antibodies  >2 publications with AATF and Inflammation
 Liver Neoplasms, Experimental Antibodies  >1 publications with AATF and Liver Neoplasms, Experimental
 Cardiovascular Diseases Antibodies  >1 publications with AATF and Cardiovascular Diseases
 Neoplasms, Experimental Antibodies  >1 publications with AATF and Neoplasms, Experimental
 Liver Neoplasms Antibodies  >1 publications with AATF and Liver Neoplasms
 Necrosis Antibodies  >1 publications with AATF and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >8 publications with AATF and Brain
 Liver Antibodies  >6 publications with AATF and Liver
 Kidney Antibodies  >4 publications with AATF and Kidney
 Prostate Antibodies  >4 publications with AATF and Prostate
 Heart Antibodies  >3 publications with AATF and Heart
 Embryonic Tissue Antibodies  >2 publications with AATF and Embryonic Tissue
 Lung Antibodies  >2 publications with AATF and Lung
 Spleen Antibodies  >1 publications with AATF and Spleen
 Colon Antibodies  >1 publications with AATF and Colon
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