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DDC elisa kit :: Goose Dopamine Decarboxylase ELISA Kit

Scan QR to view Datasheet Catalog #    MBS013780 DDC elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Dopamine Decarboxylase (DDC), ELISA Kit

 Also Known As   

Goose Dopamine Decarboxylase ELISA Kit

 Product Gene Name   

DDC elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for P05031
 Species Reactivity    Goose
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of DDC elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for DDC purchase    MBS013780 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Dopamine Decarboxylase (DDC) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing DDC. The ELISA analytical biochemical technique of the MBS013780 kit is based on DDC antibody-DDC antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect DDC antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, DDC. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for DDC. It may not necessarily be applicable to this product.
 NCBI GI #    221476190
 NCBI GeneID    35190
 NCBI Accession #    NP_523600.5 [Other Products]
 NCBI GenBank Nucleotide #    NM_078876.5 [Other Products]
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 UniProt Primary Accession #    P05031 [Other Products]
 UniProt Secondary Accession #    O18379; P05032; Q24295; Q7YSJ0; Q7YSK5; Q7YSV6; Q7Z0E1; Q7Z0E2; Q7Z0E3; Q7Z0E4; Q7Z0E5 [Other Products]
 UniProt Related Accession #    P05031 [Other Products]
 Molecular Weight    57,288 Da
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 NCBI Official Full Name    dopa decarboxylase, isoform D
 NCBI Official Synonym Full Names    Dopa decarboxylase
 NCBI Official Symbol    Ddc [Similar Products]
 NCBI Official Synonym Symbols   
5-HT; AADC; CG10697; ddc; DDC; DdcDm; DmelCG10697; fDDC; l(2)37Bl; l(2)37Ch; l(2)k02104
[Similar Products]
 NCBI Protein Information    CG10697 gene product from transcript CG10697-RB; 3,4-Dihydroxyphenylalanine decarboxylase; CG10697-PB; CG10697-PC; CG10697-PD; Ddc-PB; Ddc-PC; Ddc-PD; aromatic L-amino acid decarboxylase; dopa decarboxylase; dopa-decarboxylase; dopadecarboxylase; dopamine decarboxylase; transcription unit No. 3
 UniProt Protein Name    Aromatic-L-amino-acid decarboxylase
 UniProt Synonym Protein Names   
DOPA decarboxylase
 Protein Family    Aromatic-L-amino-acid decarboxylase
 UniProt Gene Name    Ddc [Similar Products]
 UniProt Synonym Gene Names    AADC; DDC [Similar Products]
 UniProt Entry Name    DDC_DROME
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 UniProt Comments for DDC    Function: Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Variation in the synthesis of bioamines may be a factor contributing to natural variation in life span. Ref.4

Catalytic activity: L-dopa = dopamine + CO2.5-hydroxy-L-tryptophan = 5-hydroxytryptamine + CO2.

Cofactor: Pyridoxal phosphate.

Subunit structure: Homodimer.

Tissue specificity: Hypoderm isoform isexpressed only in hypodermal epithelium and the CNS isoform onlyin central nervous system. Ref.1 Ref.10

Developmental stage: Hypoderm isoform hashigh expression levels in hypoderm during late embryogenesis, late larval development, pupariation and adult eclosion. CNS isoform hasconstant expression level in CNS throughout the life cycle. Ref.10 Ref.11

Induction: By ecdysone. In larval epidermis, expression is rapidly induced. In adult epidermis expression responds to a pulse of hormone and there is a time lag between initial exposure and appearance of DDC. Ref.12

Polymorphism: Three common molecular polymorphisms (2 in the promoter region and Phe-12) account for 15.5% of the genetic contribution to variance in life span, the polymorphisms are maintained by balancing selection.

Sequence similarities: Belongs to the group II decarboxylase family.
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 Research Articles on DDC    1. The involvement of DDC in a new pathway involved in Drosophila immunity increases the levels of dopamine, which is metabolized to produce reactive quinones that exert an antimicrobial effect on invading bacteria.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with DDC elisa kitDiseases associated with DDC elisa kit
 Products by Pathway  Pathway Diagram
 Amine-derived Hormones Pathway antibodies  Amine-derived Hormones Pathway Diagram
 Biogenic Amine Synthesis Pathway antibodies  Biogenic Amine Synthesis Pathway Diagram
 Catecholamine Biosynthesis Pathway antibodies  Catecholamine Biosynthesis Pathway Diagram
 Histidine Metabolism Pathway antibodies  Histidine Metabolism Pathway Diagram
 Histidine Metabolism Pathway antibodies  Histidine Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Phenylalanine Metabolism Pathway antibodies  Phenylalanine Metabolism Pathway Diagram
 Phenylalanine Metabolism Pathway antibodies  Phenylalanine Metabolism Pathway Diagram
 Serotonin And Melatonin Biosynthesis Pathway antibodies  Serotonin And Melatonin Biosynthesis Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >163 publications with DDC and Neoplasms
 Disease Models, Animal Antibodies  >108 publications with DDC and Disease Models, Animal
 Liver Diseases Antibodies  >107 publications with DDC and Liver Diseases
 Brain Diseases Antibodies  >89 publications with DDC and Brain Diseases
 Mental Disorders Antibodies  >59 publications with DDC and Mental Disorders
 Poisoning Antibodies  >57 publications with DDC and Poisoning
 Movement Disorders Antibodies  >54 publications with DDC and Movement Disorders
 Parkinsonian Disorders Antibodies  >49 publications with DDC and Parkinsonian Disorders
 Necrosis Antibodies  >42 publications with DDC and Necrosis
 Parkinson Disease Antibodies  >38 publications with DDC and Parkinson Disease
Organs/Tissues associated with DDC elisa kit
 Organ/Tissue Name  Pubmed Publications
 Mixed Antibodies  >39 publications with DDC and Mixed
 Head Antibodies  >20 publications with DDC and Head
 Whole Body Antibodies  >19 publications with DDC and Whole Body
 Uncharacterized Tissue Antibodies  >1 publications with DDC and Uncharacterized Tissue
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