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DAT elisa kit :: Goose Dopamine Transporter ELISA Kit

Scan QR to view Datasheet Catalog #    MBS008423 DAT elisa kit
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Dopamine Transporter (DAT), ELISA Kit

 Also Known As   

Goose Dopamine Transporter ELISA Kit

 Product Gene Name   

DAT elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 5; NC_000005.9 (1392905..1445543, complement). Location: 5p15.3
 OMIM    126455
 3D Structure    ModBase 3D Structure for Q01959
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 Species Reactivity    Goose
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of DAT elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for DAT purchase    MBS008423 is a ready-to-use microwell, strip-or-full plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Dopamine Transporter (DAT) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing DAT. The ELISA analytical biochemical technique of the MBS008423 kit is based on DAT antibody-DAT antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect DAT antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, DAT. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for DAT. It may not necessarily be applicable to this product.
 NCBI GI #    7108463
 NCBI GeneID    6531
 NCBI Accession #    AAC50179.2 [Other Products]
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 UniProt Primary Accession #    Q01959 [Other Products]
 UniProt Secondary Accession #    Q14996; A2RUN4 [Other Products]
 UniProt Related Accession #    Q01959 [Other Products]
 Molecular Weight    68,495 Da
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 NCBI Official Full Name    dopamine transporter
 NCBI Official Synonym Full Names    solute carrier family 6 (neurotransmitter transporter), member 3
 NCBI Official Symbol    SLC6A3 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    sodium-dependent dopamine transporter; DA transporter; dopamine transporter 1; solute carrier family 6 member 3; solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
 UniProt Protein Name    Sodium-dependent dopamine transporter
 UniProt Synonym Protein Names   
Solute carrier family 6 member 3
 Protein Family    D-alanine aminotransferase
 UniProt Gene Name    SLC6A3 [Similar Products]
 UniProt Synonym Gene Names    DAT1; DA transporter; DAT [Similar Products]
 UniProt Entry Name    SC6A3_HUMAN
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 NCBI Summary for DAT    This gene encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence.[provided by RefSeq, Nov 2009]
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 UniProt Comments for DAT    DAT: Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals. Defects in SLC6A3 are the cause of dystonia-parkinsonism infantile (DYTPRI). It is a neurodegenerative disorder characterized by infantile onset of parkinsonism and dystonia. Other neurologic features include global developmental delay, bradikinesia and pyramidal tract signs. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 5p15.3

Cellular Component: cell soma; axon; integral to plasma membrane; cytoplasm; integral to membrane; plasma membrane

Molecular Function: protein binding; protease binding; dopamine binding; protein complex binding; monoamine transmembrane transporter activity; protein N-terminus binding; drug binding; dopamine:sodium symporter activity; dopamine transmembrane transporter activity; receptor binding

Biological Process: response to nicotine; lactation; response to drug; dopamine transport; response to cAMP; prepulse inhibition; dopamine catabolic process; sensory perception of smell; monoamine transport; regulation of dopamine metabolic process; locomotory behavior; dopamine biosynthetic process; positive regulation of multicellular organism growth; response to cocaine; synaptic transmission; response to ethanol; neurotransmitter transport; adenohypophysis development; response to iron ion; transmembrane transport; neurotransmitter biosynthetic process; aging

Disease: Parkinsonism-dystonia, Infantile; Tobacco Addiction, Susceptibility To
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 Research Articles on DAT    1. A rare DAT haplotype, formed by the minor alleles of rs3836790 and rs27072, occurred in nearly one-third of the cocaine abusers. Other variants of DAT interact with DRD2 variants in conferring risk of lethal cocaine abuse.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with DAT elisa kitPathways associated with DAT elisa kit
 Reference Product  PubMed Publications
 DRD4 elisa kit  >154 publications with DAT and DRD4
 DRD2 elisa kit  >98 publications with DAT and DRD2
 DRD3 elisa kit  >44 publications with DAT and DRD3
 SLC18A2 elisa kit  >33 publications with DAT and SLC18A2
 SNCA elisa kit  >12 publications with DAT and SNCA
 UBC elisa kit  >2 publications with DAT and UBC
 STX1A elisa kit  >1 publications with DAT and STX1A
 PICK1 elisa kit  >1 publications with DAT and PICK1
 Products by Pathway  Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alpha-synuclein Signaling Pathway antibodies  Alpha-synuclein Signaling Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Cocaine Addiction Pathway antibodies  Cocaine Addiction Pathway Diagram
 Cocaine Addiction Pathway antibodies  Cocaine Addiction Pathway Diagram
 Dopamine Clearance From The Synaptic Cleft Pathway antibodies  Dopamine Clearance From The Synaptic Cleft Pathway Diagram
 Dopaminergic Synapse Pathway antibodies  Dopaminergic Synapse Pathway Diagram
 Dopaminergic Synapse Pathway antibodies  Dopaminergic Synapse Pathway Diagram
Diseases associated with DAT elisa kitOrgans/Tissues associated with DAT elisa kit
 Disease Name  Pubmed Publications
 Attention Deficit Disorder with Hyperactivity Antibodies  >231 publications with DAT and Attention Deficit Disorder with Hyperactivity
 Nervous System Diseases Antibodies  >197 publications with DAT and Nervous System Diseases
 Brain Diseases Antibodies  >164 publications with DAT and Brain Diseases
 Movement Disorders Antibodies  >137 publications with DAT and Movement Disorders
 Parkinsonian Disorders Antibodies  >116 publications with DAT and Parkinsonian Disorders
 Parkinson Disease Antibodies  >90 publications with DAT and Parkinson Disease
 Schizophrenia Antibodies  >75 publications with DAT and Schizophrenia
 Drug Toxicity Antibodies  >51 publications with DAT and Drug Toxicity
 Cocaine-Related Disorders Antibodies  >50 publications with DAT and Cocaine-Related Disorders
 Nerve Degeneration Antibodies  >41 publications with DAT and Nerve Degeneration
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >673 publications with DAT and Brain
 Ganglia Antibodies  >55 publications with DAT and Ganglia
 Kidney Antibodies  >39 publications with DAT and Kidney
 Lung Antibodies  >4 publications with DAT and Lung
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