NP_004114.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
17,108 Da
NCBI Official Full Name
gastric inhibitory polypeptide preproprotein
NCBI Official Synonym Full Names
gastric inhibitory polypeptide
NCBI Protein Information
gastric inhibitory polypeptide; incretin hormone; glucose-dependent insulinotropic polypeptide
UniProt Protein Name
Gastric inhibitory polypeptide
UniProt Synonym Protein Names
Glucose-dependent insulinotropic polypeptide; Incretin hormone
UniProt Synonym Gene Names
UniProt Entry Name
GIP_HUMAN
NCBI Summary for GIP
This gene encodes an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion. [provided by RefSeq, Jul 2008]
UniProt Comments for GIP
GIP: Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion. Belongs to the glucagon family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 17q21.3-q22
Cellular Component: extracellular space; cell soma; endoplasmic reticulum lumen; extracellular region
Molecular Function: hormone activity
Biological Process: response to drug; response to peptide hormone stimulus; adult locomotory behavior; positive regulation of insulin secretion; female pregnancy; response to amino acid stimulus; response to lipid; sensory perception of pain; signal transduction; endocrine pancreas development; response to organic cyclic substance; memory; response to starvation; response to selenium ion; cellular protein metabolic process; response to glucose stimulus; response to axon injury; regulation of insulin secretion
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Products associated with GIP elisa kit
Pathways associated with GIP elisa kit
Diseases associated with GIP elisa kit
Organs/Tissues associated with GIP elisa kit
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