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| Product Name
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Hormone Sensitive Lipase (HSL), ELISA Kit
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| Also Known As
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Goose Hormone Sensitive Lipase ELISA Kit
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| Product Gene Name
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[Similar Products]
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| Research Use Only
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For Research Use Only. Not for use in diagnostic procedures.
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| Request for Current Manual Insert
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| Chromosome Location
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Chromosome: 19; NC_000019.9 (42905666..42931578, complement). Location: 19q13.2
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| OMIM
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151750
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| 3D Structure
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ModBase 3D Structure for Q05469
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| Species Reactivity
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Goose
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| Assay Type
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Sandwich
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| Preparation and Storage
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Store all reagents at 2-8 degree C
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| Product Note
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Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
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| Other Notes
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Small volumes of HSL elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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| Searchable Terms for HSL purchase
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MBS021707 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Hormone Sensitive Lipase (HSL) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HSL. The ELISA analytical biochemical technique of the MBS021707 kit is based on HSL antibody-HSL antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HSL antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HSL. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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| NCBI/Uniprot data below describe general gene information for HSL. It may not necessarily be applicable to this product. |
| NCBI GI #
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21328446
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| NCBI GeneID
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3991
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| NCBI Accession #
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NP_005348.2
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[Other Products]
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| NCBI GenBank Nucleotide #
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NM_005357.2
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[Other Products]
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| UniProt Primary Accession #
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Q05469
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[Other Products]
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| UniProt Secondary Accession #
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Q3LRT2; Q6NSL7
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[Other Products]
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| UniProt Related Accession #
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Q05469
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[Other Products]
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| Molecular Weight
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116,598 Da
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| NCBI Official Full Name
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hormone-sensitive lipase
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| NCBI Official Synonym Full Names
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lipase, hormone-sensitive
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| NCBI Official Symbol
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LIPE
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[Similar Products]
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| NCBI Official Synonym Symbols
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HSL; LHS
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[Similar Products]
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| NCBI Protein Information
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hormone-sensitive lipase; hormone-sensitive lipase testicular isoform
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| UniProt Protein Name
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Hormone-sensitive lipase
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| UniProt Gene Name
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LIPE
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[Similar Products]
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| UniProt Synonym Gene Names
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HSL
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[Similar Products]
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| UniProt Entry Name
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LIPS_HUMAN
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| NCBI Summary for HSL
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The protein encoded by this gene has a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesteryl esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids. [provided by RefSeq, Jul 2008]
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| UniProt Comments for HSL
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HSL: hormone sensitive lipase is a lipolytic enzyme of the 'GDXG' family. Plays a rate limiting step in triglyceride lipolysis. In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production. Rapidly activated by cAMP-dependent phosphorylation under the influence of catecholamines. Dephosphorylation and inactivation are controlled by insulin.
Protein type: EC 3.1.1.79; Lipase
Chromosomal Location of Human Ortholog: 19q13.2
Cellular Component: lipid particle; caveola; cytosol
Molecular Function: hormone-sensitive lipase activity; triacylglycerol lipase activity; protein binding; protein kinase binding
Biological Process: cholesterol metabolic process; triacylglycerol catabolic process; diacylglycerol catabolic process; protein amino acid phosphorylation; lipid catabolic process; long-chain fatty acid catabolic process
Disease: Abdominal Obesity-metabolic Syndrome 4
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| Research Articles on HSL
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1. M. leprae suppresses lipid degradation through inhibition of HSL expression.
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| Precautions
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All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
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| Disclaimer
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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| Products associated with HSL elisa kit | Pathways associated with HSL elisa kit |
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| Diseases associated with HSL elisa kit | Organs/Tissues associated with HSL elisa kit |
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ELISA Kit 
