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IFI16 elisa kit :: Goose Interferon Gamma Inducible Protein 16 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS016369 IFI16 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Interferon Gamma Inducible Protein 16 (IFI16), ELISA Kit

 Also Known As   

Goose Interferon Gamma Inducible Protein 16 ELISA Kit

 Product Gene Name   

IFI16 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    147569
 3D Structure    ModBase 3D Structure for P38484
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 Species Reactivity    Goose
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IFI16 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IFI16 purchase    MBS016369 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Interferon Gamma Inducible Protein 16 (IFI16) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IFI16. The ELISA analytical biochemical technique of the MBS016369 kit is based on IFI16 antibody-IFI16 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IFI16 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IFI16. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for IFI16. It may not necessarily be applicable to this product.
 NCBI GI #    47419934
 NCBI GeneID    3460
 NCBI Accession #    NP_005525.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_005534.3 [Other Products]
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 UniProt Primary Accession #    P38484 [Other Products]
 UniProt Secondary Accession #    Q9BTL5 [Other Products]
 UniProt Related Accession #    P38484 [Other Products]
 Molecular Weight    37,806 Da
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 NCBI Official Full Name    interferon gamma receptor 2
 NCBI Official Synonym Full Names    interferon gamma receptor 2 (interferon gamma transducer 1)
 NCBI Official Symbol    IFNGR2 [Similar Products]
 NCBI Official Synonym Symbols   
AF-1; IFGR2; IFNGT1
[Similar Products]
 NCBI Protein Information    interferon gamma receptor 2; IFN-gamma-R2; IFN-gamma receptor 2; interferon gamma transducer 1; interferon gamma receptor beta chain; interferon gamma receptor accessory factor 1; interferon gamma receptor accessory factor-1
 UniProt Protein Name    Interferon gamma receptor 2
 UniProt Synonym Protein Names   
Interferon gamma receptor accessory factor 1; AF-1; Interferon gamma transducer 1
 Protein Family    Gamma-interferon-inducible protein
 UniProt Gene Name    IFNGR2 [Similar Products]
 UniProt Synonym Gene Names    IFNGT1; IFN-gamma receptor 2; IFN-gamma-R2; AF-1 [Similar Products]
 UniProt Entry Name    INGR2_HUMAN
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 NCBI Summary for IFI16    This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance. [provided by RefSeq, Jul 2008]
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 UniProt Comments for IFI16    IFNGR2: Part of the receptor for interferon gamma. Required for signal transduction. This accessory factor is an integral part of the IFN-gamma signal transduction pathway and is likely to interact with GAF, JAK1, and/or JAK2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD); also known as familial disseminated atypical mycobacterial infection. This rare condition confers predisposition to illness caused by moderately virulent mycobacterial species, such as Bacillus Calmette-Guerin (BCG) vaccine and environmental non-tuberculous mycobacteria, and by the more virulent Mycobacterium tuberculosis. Other microorganisms rarely cause severe clinical disease in individuals with susceptibility to mycobacterial infections, with the exception of Salmonella which infects less than 50% of these individuals. The pathogenic mechanism underlying MSMD is the impairment of interferon-gamma mediated immunity, whose severity determines the clinical outcome. Some patients die of overwhelming mycobacterial disease with lepromatous-like lesions in early childhood, whereas others develop, later in life, disseminated but curable infections with tuberculoid granulomas. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance. Belongs to the type II cytokine receptor family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 21q22.11

Cellular Component: endoplasmic reticulum; integral to plasma membrane; plasma membrane; integral to membrane

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; interferon-gamma receptor activity

Biological Process: cell surface receptor linked signal transduction; response to virus; cytokine and chemokine mediated signaling pathway

Disease: Immunodeficiency 28
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 Research Articles on IFI16    1. We report a molecular study of the two known patients with autosomal recessive, partial interferon-gamma receptor (IFN-gammaR)2 deficiency
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with IFI16 elisa kitPathways associated with IFI16 elisa kit
 Reference Product  PubMed Publications
 IFNGR1 elisa kit  >42 publications with IFI16 and IFNGR1
 STAT1 elisa kit  >25 publications with IFI16 and STAT1
 JAK2 elisa kit  >7 publications with IFI16 and JAK2
 JAK1 elisa kit  >4 publications with IFI16 and JAK1
 Products by Pathway  Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 HIF-1 Signaling Pathway antibodies  HIF-1 Signaling Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Inflammatory Bowel Disease (IBD) Pathway antibodies  Inflammatory Bowel Disease (IBD) Pathway Diagram
Diseases associated with IFI16 elisa kitOrgans/Tissues associated with IFI16 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >23 publications with IFI16 and Neoplasms
 Inflammation Antibodies  >10 publications with IFI16 and Inflammation
 Mycobacterium Infections, Nontuberculous Antibodies  >8 publications with IFI16 and Mycobacterium Infections, Nontuberculous
 Liver Diseases Antibodies  >6 publications with IFI16 and Liver Diseases
 Breast Neoplasms Antibodies  >6 publications with IFI16 and Breast Neoplasms
 Necrosis Antibodies  >6 publications with IFI16 and Necrosis
 Cardiovascular Diseases Antibodies  >4 publications with IFI16 and Cardiovascular Diseases
 Carcinoma, Hepatocellular Antibodies  >3 publications with IFI16 and Carcinoma, Hepatocellular
 Thrombocytopenia Antibodies  >2 publications with IFI16 and Thrombocytopenia
 Heart Diseases Antibodies  >2 publications with IFI16 and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >28 publications with IFI16 and Blood
 Liver Antibodies  >6 publications with IFI16 and Liver
 Skin Antibodies  >5 publications with IFI16 and Skin
 Kidney Antibodies  >4 publications with IFI16 and Kidney
 Prostate Antibodies  >4 publications with IFI16 and Prostate
 Muscle Antibodies  >3 publications with IFI16 and Muscle
 Vascular Antibodies  >3 publications with IFI16 and Vascular
 Brain Antibodies  >3 publications with IFI16 and Brain
 Lymph Node Antibodies  >2 publications with IFI16 and Lymph Node
 Thyroid Antibodies  >2 publications with IFI16 and Thyroid
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