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LIF elisa kit :: Goose Leukemia Inhibitory Factor ELISA Kit

Scan QR to view Datasheet Catalog #    MBS008671 LIF elisa kit
Unit / Price
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Leukemia Inhibitory Factor (LIF), ELISA Kit

 Also Known As   

Goose Leukemia Inhibitory Factor ELISA Kit

 Product Gene Name   

LIF elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 22; NC_000022.10 (30636436..30642840, complement). Location: 22q12.2
 OMIM    159540
 3D Structure    ModBase 3D Structure for P15018
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 Species Reactivity    Goose
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of LIF elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for LIF purchase    MBS008671 is a ready-to-use microwell, strip-or-full plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Leukemia Inhibitory Factor (LIF) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing LIF. The ELISA analytical biochemical technique of the MBS008671 kit is based on LIF antibody-LIF antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LIF antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LIF. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for LIF. It may not necessarily be applicable to this product.
 NCBI GI #    4504991
 NCBI GeneID    3976
 NCBI Accession #    NP_002300.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002309.4 [Other Products]
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 UniProt Primary Accession #    P15018 [Other Products]
 UniProt Secondary Accession #    Q52LZ2; B2RCW7; B5MC23 [Other Products]
 UniProt Related Accession #    P15018 [Other Products]
 Molecular Weight    22,008 Da
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 NCBI Official Full Name    leukemia inhibitory factor isoform 1
 NCBI Official Synonym Full Names    leukemia inhibitory factor
 NCBI Official Symbol    LIF [Similar Products]
 NCBI Official Synonym Symbols   
CDF; DIA; HILDA; MLPLI
[Similar Products]
 NCBI Protein Information    leukemia inhibitory factor; D factor; human interleukin in DA cells; melanoma-derived LPL inhibitor; differentiation-inducing factor; hepatocyte-stimulating factor III; cholinergic differentiation factor; differentiation-stimulating factor; differentiation inhibitory activity
 UniProt Protein Name    Leukemia inhibitory factor
 UniProt Synonym Protein Names   
Differentiation-stimulating factor; D factor; Melanoma-derived LPL inhibitor
 Protein Family    Leukemia inhibitory factor
 UniProt Gene Name    LIF [Similar Products]
 UniProt Synonym Gene Names    HILDA; LIF; D factor; MLPLI [Similar Products]
 UniProt Entry Name    LIF_HUMAN
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 NCBI Summary for LIF    The protein encoded by this gene is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
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 UniProt Comments for LIF    LIF: LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes. Belongs to the LIF/OSM family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 22q12.2

Cellular Component: extracellular space; cytoplasm

Molecular Function: growth factor activity; leukemia inhibitory factor receptor binding; cytokine activity; receptor binding

Biological Process: transcription from RNA polymerase II promoter; multicellular organismal development; negative regulation of hormone secretion; leukemia inhibitory factor signaling pathway; tyrosine phosphorylation of Stat3 protein; decidualization; positive regulation of tyrosine phosphorylation of Stat3 protein; negative regulation of cell proliferation; positive regulation of MAPKKK cascade; negative regulation of meiosis; positive regulation of cell proliferation; positive regulation of macrophage differentiation; muscle morphogenesis; positive regulation of peptidyl-serine phosphorylation of STAT protein; positive regulation of astrocyte differentiation; stem cell maintenance; positive regulation of peptidyl-serine phosphorylation; positive regulation of tyrosine phosphorylation of Stat1 protein; positive regulation of peptidyl-tyrosine phosphorylation; neuron development; blood vessel remodeling; immune response; positive regulation of transcription from RNA polymerase II promoter; alveolus development; embryo implantation
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 Research Articles on LIF    1. LIF is a contraction-induced myokine, potentially acting in an autocrine or paracrine fashion to promote skeletal muscle satellite cell proliferation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with LIF elisa kitPathways associated with LIF elisa kit
 Reference Product  PubMed Publications
 KITLG elisa kit  >956 publications with LIF and KITLG
 JUN elisa kit  >606 publications with LIF and JUN
 STAT3 elisa kit  >496 publications with LIF and STAT3
 LIFR elisa kit  >449 publications with LIF and LIFR
 IL6ST elisa kit  >234 publications with LIF and IL6ST
 NANOG elisa kit  >154 publications with LIF and NANOG
 STAT1 elisa kit  >83 publications with LIF and STAT1
 DIF elisa kit  >9 publications with LIF and DIF
 TP53 elisa kit  >4 publications with LIF and TP53
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 MicroRNAs In Cardiomyocyte Hypertrophy Pathway antibodies  MicroRNAs In Cardiomyocyte Hypertrophy Pathway Diagram
 TGF Beta Signaling Pathway antibodies  TGF Beta Signaling Pathway Diagram
 TNF Signaling Pathway antibodies  TNF Signaling Pathway Diagram
 TNF Signaling Pathway antibodies  TNF Signaling Pathway Diagram
Diseases associated with LIF elisa kitOrgans/Tissues associated with LIF elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >701 publications with LIF and Neoplasms
 Necrosis Antibodies  >265 publications with LIF and Necrosis
 Inflammation Antibodies  >251 publications with LIF and Inflammation
 Cardiovascular Diseases Antibodies  >182 publications with LIF and Cardiovascular Diseases
 Female Urogenital Diseases Antibodies  >150 publications with LIF and Female Urogenital Diseases
 Infertility, Female Antibodies  >99 publications with LIF and Infertility, Female
 Neoplasms, Experimental Antibodies  >81 publications with LIF and Neoplasms, Experimental
 Heart Diseases Antibodies  >69 publications with LIF and Heart Diseases
 Lung Diseases Antibodies  >64 publications with LIF and Lung Diseases
 Hypertrophy Antibodies  >59 publications with LIF and Hypertrophy
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >479 publications with LIF and Bone
 Brain Antibodies  >462 publications with LIF and Brain
 Uterus Antibodies  >328 publications with LIF and Uterus
 Embryonic Tissue Antibodies  >316 publications with LIF and Embryonic Tissue
 Muscle Antibodies  >315 publications with LIF and Muscle
 Bone Marrow Antibodies  >237 publications with LIF and Bone Marrow
 Skin Antibodies  >176 publications with LIF and Skin
 Lung Antibodies  >132 publications with LIF and Lung
 Placenta Antibodies  >128 publications with LIF and Placenta
 Eye Antibodies  >108 publications with LIF and Eye
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